Gefitinib Synergizes with Irinotecan to Suppress Hepatocellular Carcinoma via Antagonizing Rad51-Mediated DNA-Repair
出版年份 2016 全文链接
标题
Gefitinib Synergizes with Irinotecan to Suppress Hepatocellular Carcinoma via Antagonizing Rad51-Mediated DNA-Repair
作者
关键词
DNA damage, Apoptosis, Hepatocellular carcinoma, Cancer treatment, Cell proliferation, Cell staining, Homologous recombination, Toxicity
出版物
PLoS One
Volume 11, Issue 1, Pages e0146968
出版商
Public Library of Science (PLoS)
发表日期
2016-01-12
DOI
10.1371/journal.pone.0146968
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Emerging trends in hepatocellular carcinoma incidence and mortality
- (2014) Basile Njei et al. HEPATOLOGY
- The Use of Olaparib (AZD2281) Potentiates SN-38 Cytotoxicity in Colon Cancer Cells by Indirect Inhibition of Rad51-Mediated Repair of DNA Double-Strand Breaks
- (2014) M. Tahara et al. MOLECULAR CANCER THERAPEUTICS
- Q6, a novel hypoxia-targeted drug, regulates hypoxia-inducible factor signaling via an autophagy-dependent mechanism in hepatocellular carcinoma
- (2013) Xiao-Wen Liu et al. Autophagy
- An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells
- (2011) M Yashiro et al. BRITISH JOURNAL OF CANCER
- Phase I study of irinotecan and gefitinib in patients with gefitinib treatment failure for non-small cell lung cancer
- (2011) A Horiike et al. BRITISH JOURNAL OF CANCER
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Management of hepatocellular carcinoma: An update
- (2011) Jordi Bruix et al. HEPATOLOGY
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- Phase I Evaluation of Telatinib, a Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, in Combination with Irinotecan and Capecitabine in Patients with Advanced Solid Tumors
- (2010) M. H. G. Langenberg et al. CLINICAL CANCER RESEARCH
- Involvement of Rad51 in cytotoxicity induced by epidermal growth factor receptor inhibitor (gefitinib, IressaR) and chemotherapeutic agents in human lung cancer cells
- (2008) J.-C. Ko et al. CARCINOGENESIS
- Diagnosis and Treatment of Hepatocellular Carcinoma
- (2008) Hashem B. El-Serag et al. GASTROENTEROLOGY
- Novel advancements in the management of hepatocellular carcinoma in 2008
- (2008) Josep M. Llovet et al. JOURNAL OF HEPATOLOGY
- Role of repair protein Rad51 in regulating the response to gefitinib in human non-small cell lung cancer cells
- (2008) J.-C. Ko et al. MOLECULAR CANCER THERAPEUTICS
- Sorafenib in Advanced Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. NEW ENGLAND JOURNAL OF MEDICINE
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