Genetic Modifiers of Duchenne Muscular Dystrophy and Dilated Cardiomyopathy

Left Ventricular Dysfunction in Duchenne Muscular Dystrophy and Genotype

(2014) Mahi L. Ashwath et al.   AMERICAN JOURNAL OF CARDIOLOGY

Eccentric muscle challenge shows osteopontin polymorphism modulation of muscle damage

(2014) W. L. Barfield et al.   HUMAN MOLECULAR GENETICS

Cooperative international neuromuscular research group duchenne natural history study demonstrates insufficient diagnosis and treatment of cardiomyopathy in duchenne muscular dystrophy

(2014) Christopher Spurney et al.   MUSCLE & NERVE

6 Minute Walk Test in Duchenne MD Patients with Different Mutations: 12 Month Changes

(2014) Marika Pane et al.   PLoS One

Targeting latent TGF  release in muscular dystrophy

(2014) E. Ceco et al.   Science Translational Medicine

Modifying muscular dystrophy through transforming growth factor-β

(2013) Ermelinda Ceco et al.   FEBS Journal

Oral Corticosteroids and Onset of Cardiomyopathy in Duchenne Muscular Dystrophy

(2013) Brent J. Barber et al.   JOURNAL OF PEDIATRICS

Alterations in Osteopontin Modify Muscle Size in Females in Both Humans and Mice

(2013) ERIC P. HOFFMAN et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

LTBP4genotype predicts age of ambulatory loss in duchenne muscular dystrophy

(2012) Kevin M. Flanigan et al.   ANNALS OF NEUROLOGY

Osteopontin deficiency delays inflammatory infiltration and the onset of muscle regeneration in a mouse model of muscle injury

(2012) K. Uaesoontrachoon et al.   Disease Models & Mechanisms

TGFBR2 but not SPP1 genotype modulates osteopontin expression in Duchenne muscular dystrophy muscle

(2012) Luisa Piva et al.   JOURNAL OF PATHOLOGY

Importance of SPP1 genotype as a covariate in clinical trials in Duchenne muscular dystrophy

(2012) L. Bello et al.   NEUROLOGY

Glucocorticoid-Treated Mice Are an Inappropriate Positive Control for Long-Term Preclinical Studies in the mdx Mouse

(2012) Arpana Sali et al.   PLoS One

Osteopontin is highly expressed in severely dystrophic muscle and seems to play a role in muscle regeneration and fibrosis

(2011) Simona Zanotti et al.   HISTOPATHOLOGY

American Society of Echocardiography Clinical Recommendations for Multimodality Cardiovascular Imaging of Patients with Hypertrophic Cardiomyopathy

(2011) Sherif F. Nagueh et al.   JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

Cardiomyopathy of duchenne muscular dystrophy: Current understanding and future directions

(2011) Christopher F. Spurney   MUSCLE & NERVE

Osteopontin in Cardiovascular Disease

(2010) Alfonso H. Waller et al.   Cardiology in Review

Osteopontin Expression in Cardiomyocytes Induces Dilated Cardiomyopathy

(2010) Marie-Ange Renault et al.   Circulation-Heart Failure

SPP1 genotype is a determinant of disease severity in Duchenne muscular dystrophy

(2010) E. Pegoraro et al.   NEUROLOGY

Contrasting effects of steroids and angiotensin-converting-enzyme inhibitors in a mouse model of dystrophin-deficient cardiomyopathy

(2009) Ralf Bauer et al.   EUROPEAN JOURNAL OF HEART FAILURE

Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-β

(2009) Sylvia A. Vetrone et al.   JOURNAL OF CLINICAL INVESTIGATION

Latent TGF-β–binding protein 4 modifies muscular dystrophy in mice

(2009) Ahlke Heydemann et al.   JOURNAL OF CLINICAL INVESTIGATION

Steroid treatment causes deterioration of myocardial function in the  -sarcoglycan-deficient mouse model for dilated cardiomyopathy

(2008) R. Bauer et al.   CARDIOVASCULAR RESEARCH

Osteopontin: Role in immune regulation and stress responses

(2008) Kathryn X. Wang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Osteopontin and skeletal muscle myoblasts: Association with muscle regeneration and regulation of myoblast function in vitro

(2008) Kitipong Uaesoontrachoon et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Corticosteroid treatment retards development of ventricular dysfunction in Duchenne muscular dystrophy

(2008) Larry W. Markham et al.   NEUROMUSCULAR DISORDERS