标题
IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas
作者
关键词
Cancer immunotherapy, Basic cancer research, Sarcomas, T cells, Sarcoma cells, Mouse models, Cancer treatment, T cell receptors
出版物
PLoS One
Volume 10, Issue 7, Pages e0133152
出版商
Public Library of Science (PLoS)
发表日期
2015-07-15
DOI
10.1371/journal.pone.0133152
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Human Epidermal Growth Factor Receptor 2 (HER2) –Specific Chimeric Antigen Receptor–Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma
- (2015) Nabil Ahmed et al. JOURNAL OF CLINICAL ONCOLOGY
- Adoptive cellular therapy: A race to the finish line
- (2015) Carl H. June et al. Science Translational Medicine
- Antibody-modified T cells: CARs take the front seat for hematologic malignancies
- (2014) M. V. Maus et al. BLOOD
- CAR T Cells for Solid Tumors
- (2014) Sunitha Kakarla et al. CANCER JOURNAL
- Randomized, Phase III Trial of First-Line Figitumumab in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone in Patients With Advanced Non–Small-Cell Lung Cancer
- (2014) Corey J. Langer et al. JOURNAL OF CLINICAL ONCOLOGY
- Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
- (2014) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ovarian cancer stem cells express ROR1, which can be targeted for anti–cancer-stem-cell therapy
- (2014) Suping Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The receptor tyrosine kinase ROR1 – An oncofetal antigen for targeted cancer therapy
- (2014) Mohammad Hojjat-Farsangi et al. SEMINARS IN CANCER BIOLOGY
- T-helper I immunity, specific for the breast cancer antigen insulin-like growth factor-I receptor (IGF-IR), is associated with increased adiposity
- (2013) Denise L. Cecil et al. BREAST CANCER RESEARCH AND TREATMENT
- A Multiantigen Vaccine Targeting Neu, IGFBP-2, and IGF-IR Prevents Tumor Progression in Mice with Preinvasive Breast Disease
- (2013) M. L. Disis et al. Cancer Prevention Research
- Targeting ROR1 Inhibits Epithelial-Mesenchymal Transition and Metastasis
- (2013) B. Cui et al. CANCER RESEARCH
- PD-1- and CTLA-4-Based Inhibitory Chimeric Antigen Receptors (iCARs) Divert Off-Target Immunotherapy Responses
- (2013) V. D. Fedorov et al. Science Translational Medicine
- CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia
- (2013) R. J. Brentjens et al. Science Translational Medicine
- Type 1 insulin-like growth factor receptor targeted therapies in pediatric cancer
- (2013) Michael J. Wagner et al. Frontiers in Oncology
- The ganglioside antigen GD2 is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting
- (2012) S Kailayangiri et al. BRITISH JOURNAL OF CANCER
- Crosstalk between ROR1 and the Pre-B Cell Receptor Promotes Survival of t(1;19) Acute Lymphoblastic Leukemia
- (2012) Vincent T. Bicocca et al. CANCER CELL
- NKX2-1/TITF1/TTF-1-Induced ROR1 Is Required to Sustain EGFR Survival Signaling in Lung Adenocarcinoma
- (2012) Tomoya Yamaguchi et al. CANCER CELL
- Insulin-like Growth Factor Receptor Inhibitors: Baby or the Bathwater?
- (2012) D. Yee JNCI-Journal of the National Cancer Institute
- Targeting malignant B cells with an immunotoxin against ROR1
- (2012) Sivasubramanian Baskar et al. mAbs
- ROR1 Is Expressed in Human Breast Cancer and Associated with Enhanced Tumor-Cell Growth
- (2012) Suping Zhang et al. PLoS One
- Restricted Cell Surface Expression of Receptor Tyrosine Kinase ROR1 in Pediatric B-Lineage Acute Lymphoblastic Leukemia Suggests Targetability with Therapeutic Monoclonal Antibodies
- (2012) Hema Dave et al. PLoS One
- Genetically Modified T cells Targeting Interleukin-11 Receptor -Chain Kill Human Osteosarcoma Cells and Induce the Regression of Established Osteosarcoma Lung Metastases
- (2011) G. Huang et al. CANCER RESEARCH
- R1507, a Monoclonal Antibody to the Insulin-Like Growth Factor 1 Receptor, in Patients With Recurrent or Refractory Ewing Sarcoma Family of Tumors: Results of a Phase II Sarcoma Alliance for Research Through Collaboration Study
- (2011) Alberto S. Pappo et al. JOURNAL OF CLINICAL ONCOLOGY
- Preliminary Efficacy of the Anti-Insulin–Like Growth Factor Type 1 Receptor Antibody Figitumumab in Patients With Refractory Ewing Sarcoma
- (2011) Heribert Juergens et al. JOURNAL OF CLINICAL ONCOLOGY
- Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1
- (2011) Paul F. Robbins et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase I/II Trial and Pharmacokinetic Study of Cixutumumab in Pediatric Patients With Refractory Solid Tumors and Ewing Sarcoma: A Report From the Children's Oncology Group
- (2011) Suman Malempati et al. JOURNAL OF CLINICAL ONCOLOGY
- ROR1 is expressed on hematogones (non-neoplastic human B-lymphocyte precursors) and a minority of precursor-B acute lymphoblastic leukemia
- (2011) H. Elizabeth Broome et al. LEUKEMIA RESEARCH
- Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
- (2011) David L. Porter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Therapeutic Potential and Challenges of Targeting Receptor Tyrosine Kinase ROR1 with Monoclonal Antibodies in B-Cell Malignancies
- (2011) Jiahui Yang et al. PLoS One
- The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor
- (2010) M. Hudecek et al. BLOOD
- Stable gene transfer and expression in cord blood-derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system
- (2009) X. Xue et al. BLOOD
- Adoptive cell therapy for the treatment of patients with metastatic melanoma
- (2009) Steven A Rosenberg et al. CURRENT OPINION IN IMMUNOLOGY
- 4-1BB and CD28 Signaling Plays a Synergistic Role in Redirecting Umbilical Cord Blood T Cells Against B-Cell Malignancies
- (2009) Syam Tammana et al. HUMAN GENE THERAPY
- Immunotherapy for Osteosarcoma: Genetic Modification of T cells Overcomes Low Levels of Tumor Antigen Expression
- (2009) Nabil Ahmed et al. MOLECULAR THERAPY
- GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance
- (2009) W Luo et al. ONCOGENE
- Sleeping Beauty Transposon‐mediated Engineering of Human Primary T Cells for Therapy of CD19+ Lymphoid Malignancies
- (2008) Xin Huang et al. MOLECULAR THERAPY
- Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
- (2008) Martin A Pule et al. NATURE MEDICINE
- EWS/FLI Mediates Transcriptional Repression via NKX2.2 during Oncogenic Transformation in Ewing's Sarcoma
- (2008) Leah A. Owen et al. PLoS One
- Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a
- (2008) T. Fukuda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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