Article
Geriatrics & Gerontology
Fang-Lin Kuo, Chia-Ming Yen, Hung-Ju Chen, Zih-Yong Liao, Yen Lee
Summary: The study found that mobility difficulty increased significantly over time for participants aged 60 and above, with a higher likelihood of repeated falls at the age of 70. Older age, higher level of mobility difficulty, lower cognitive status, living alone, more comorbid illnesses, walking device use, longer time in physical activities, and elevated depressive symptoms were all associated with an increased probability of repeated falls.
Article
Geriatrics & Gerontology
Felipe Salech, Carlos Marquez, Lydia Lera, Barbara Angel, Rodrigo Saguez, Cecilia Albala
Summary: This study aimed to describe the prevalence of osteosarcopenia in Chilean community-dwelling older adults and its association with falls, fractures, and mortality. Osteosarcopenia was found to be common among older adults and was associated with an increased risk of falls, fractures, functional impairment, and mortality.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Health Care Sciences & Services
Avishai M. Tsur, Paula David, Abdulla Watad, Daniel Nissan, Arnon D. Cohen, Howard Amital
Summary: This study found that patients with ankylosing spondylitis are more likely to develop hip fractures earlier and more frequently compared to a matched cohort. It suggests that these patients might benefit from more proactive screening, mitigation, and prevention of risk factors for hip fractures.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Geriatrics & Gerontology
Gustavo Duque, Sandra Iuliano, Jacqueline C. T. Close, Mizhgan Fatima, Kirtan Ganda, Stefanie Bird, Ben Kirk, Mary Levidiotis, Catherine M. Said, Alexandra Papaioannou, Charles A. Inderjeeth
Summary: Osteoporosis is often overlooked and undertreated in people living in Residential Aged Care Facilities, despite their higher risk of fractures compared to community-dwelling individuals. In Australia, a series of Consensus Conferences have been held to update guidelines and provide valuable guidance for healthcare practitioners working in RACFs.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Geriatrics & Gerontology
Hanatsu Nagano, W. A. Sparrow, Katsuyoshi Mizukami, Eri Sarashina, Rezaul Begg
Summary: In this study, it was found that step length decreases as age increases from 50 to 70 years old, with MFC height decreasing from 60 years old and more variability in MFC appearing in the 70s. More symmetrical gait patterns were associated with higher MFC height.
Article
Orthopedics
Yimin Dong, Yayun Zhang, Kehan Song, Honglei Kang, Dawei Ye, Feng Li
Summary: Hip fractures are associated with high risk of death and decreased quality of life. Understanding the epidemiology and burden of hip fractures by country, age, gender, and sociodemographic factors is important for healthcare policymaking and clinical practice. The Global Burden of Disease study provides valuable information on the incidence and burden of hip fractures.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2023)
Article
Endocrinology & Metabolism
W. D. Leslie, L. Yan, L. M. Lix, S. N. Morin
Summary: The study found that the risk of recurrent fracture following a first major osteoporotic fracture remains elevated over 10 years, with modest and inconsistent attenuation in risk over time. Time dependency in early fracture risk was observed to be inconsistent, especially in women over the age of 65.
OSTEOPOROSIS INTERNATIONAL
(2022)
Article
Geriatrics & Gerontology
Mei-Ling Ge, Nadia M. Chu, Eleanor M. Simonsick, Judith D. Kasper, Qian-Li Xue
Summary: This study examined the association between the onset of physical frailty before, after, or in concert with cognitive impairment and fall incidence in older adults. The results showed that older adults experiencing both cognitive impairment and frailty had the greatest risk of repeated falls. Fall risk screening should take into account the order and timing of onset of physical frailty and cognitive impairment.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2023)
Article
Geriatrics & Gerontology
Jacqueline Giovanna De Roza, David Wei Liang Ng, Blessy Koottappal Mathew, Teena Jose, Ling Jia Goh, Chunyan Wang, Cindy Seok Chin Soh, Kar Cheng Goh
Summary: Fear of falling has significant implications for activity restriction, functional decline, and reduced quality of life in older adults. This study found that Malay ethnicity, marital status, use of walking aids, and frailty were significant factors associated with high levels of fear of falling.
Article
Geriatrics & Gerontology
Caitlin McArthur, George Ioannidis, Micaela Jantzi, Loretta Hillier, Jonathan D. Adachi, Lora Giangregorio, John Hirdes, Alexandra Papaioannou
Summary: The study aimed to identify factors predicting 1-year incident hip and major osteoporotic non-hip fractures in home care recipients, showing that cognitive impairment and wandering were most predictive of hip fractures, while being female and experiencing a previous fracture were most predictive of non-hip fractures. Additional unique characteristics of home care recipients increase their fracture risk, suggesting the need for modified fracture risk assessment tools and prevention strategies.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Geriatrics & Gerontology
Z. Lu, Y. Er, Y. Zhan, X. Deng, Y. Jin, P. Ye, L. Duan
Summary: The study revealed a significant association between frailty status and an increased risk of falls among middle-aged and older Chinese participants. The risk of falls was higher with each 0.01 increment in the frailty index, particularly for those classified as pre-frail and frail. Screening and recognizing frailty status is crucial for fall prevention among middle-aged and older adults in the community.
JOURNAL OF NUTRITION HEALTH & AGING
(2021)
Article
Geriatrics & Gerontology
Nurul Fatin Malek Rivan, Devinder Kaur Ajit Singh, Suzana Shahar, Goh Jing Wen, Nor Fadilah Rajab, Normah Che Din, Hazlina Mahadzir, Mohd Zul Amin Kamaruddin
Summary: Cognitive frailty, a combination of physical frailty and cognitive impairment, is a robust predictor of falls, injuries, and disability in older adults. Early multi-domain preventive and management strategies are crucial to decrease further functional decline and promote independence in this population.
Article
Cell Biology
Yujian Song, Yujiao Deng, Jianhua Li, Benchuan Hao, Yulun Cai, Jianqiao Chen, Haiyan Shi, Weihao Xu
Summary: Research indicates that falls among Chinese community-dwelling oldest olds are associated with systolic blood pressure and frailty, while diastolic blood pressure and pre-frailty are not significantly linked to falls.
Article
Geriatrics & Gerontology
Ling Koh, Lynette Mackenzie, Mandy Meehan, Diane Grayshon, Meryl Lovarini
Summary: This study explored the understanding and experiences of falls among community-dwelling adults aged 50 years and over living with mental illness, and identified falls prevention strategies valued by this population. The results revealed limited understanding of falls risk factors and a lack of help-seeking behavior after falls. Consequences of falls included physical injuries and negative emotional impacts. Although participants expressed concern about future falls, their prevention strategy was simply to be careful. Tailored fall prevention interventions are needed for this population.
AGING & MENTAL HEALTH
(2023)
Article
Health Care Sciences & Services
Lucia Prieto-Contreras, Francisco M. Martinez-Arnau, David Sancho-Cantus, Laura Cubero-Plazas, Pilar Perez-Ros
Summary: This study aims to assess the prevalence of falls in community-dwelling frail older people aged 70 years and older, and identifies screening strategies based on comprehensive geriatric assessments to detect increased risk of falling and recurrent falling. The study found that among the 229 participants, 121 (54.9%) had fallen in the previous 12 months, and 20 of these (16.5%) were recurrent fallers (>= 2 falls). A score of 20 points or more on the Falls Efficacy Scale International is predictive of falling, with a sensitivity of 51.7% and a specificity of 73.9%. Polypharmacy, Short Physical Performance Battery score of 8 points or less, and Falls Efficacy Scale International score of 20 points or more can be used to screen for recurrent falling.
Article
Geriatrics & Gerontology
Yu Chen, Shih-Tsung Huang, Tsui-Chuan Hsu, Li-Ning Peng, Fei-Yuan Hsiao, Liang-Kung Chen
Summary: This study examines prescription cascades among older individuals using prescription sequence symmetry analysis (PSSA). The results indicate the presence of prescription cascades in cardiovascular medications, but with a low effect size.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Geriatrics & Gerontology
Pei-Chin Yu, Chia-Chia Hsu, Wei-Ju Lee, Chih-Kuang Liang, Ming-Yueh Chou, Ming-Hsien Lin, Fei-Yuan Hsiao, Li-Ning Peng, Liang-Kung Chen
Summary: The study investigated the roles of muscle-to-fat ratio (MFR) with different definitions in the elderly population, revealing that low MFR was associated with unfavorable body composition, poor functional performance, high cardiometabolic risk, and adverse clinical outcomes.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Nutrition & Dietetics
Hsien-Hao Huang, Tse-Yao Wang, Shan-Fan Yao, Pei-Ying Lin, Julia Chia-Yu Chang, Li-Ning Peng, Liang-Kung Chen, David Hung-Tsang Yen
Summary: This study investigated the relationship between sarcopenia and gastric mobility, as well as the concentration of gastrointestinal hormones in older patients. The results showed that older people with sarcopenia had significantly higher plasma concentrations of anorexigenic gastrointestinal hormones.
Article
Pharmacology & Pharmacy
Chih-Kuang Liang, Ming-Yueh Chou, Ying-Hsin Hsu, Yu-Chun Wang, Mei-Chen Liao, Miao-Ting Chen, Pei-Yu Hsiao, Liang-Kung Chen, Yu-Te Lin
Summary: This study analyzed data from older patients aged >= 65 years to examine the correlations between drug-use indicators and postdischarge healthcare services use. The study found that potentially inappropriate medications, polypharmacy, and anticholinergic burden were associated with future healthcare service utilization. These associations were particularly significant among patients without dementia, aged >80 years, and with frailty.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Article
Health Care Sciences & Services
Shih-Tsung Huang, Fei-Yuan Hsiao, Tsung-Hsien Tsai, Pei-Jung Chen, Li-Ning Peng, Liang-Kung Chen
Summary: This study used machine learning methods to identify 49 hierarchical disease triplet clusters related to dementia development, with cardiovascular and cerebrovascular diseases playing leading roles and mental conditions, locomotion difficulties, infections, and nonspecific neurological conditions playing supporting roles. This research is of great significance for the prevention and care of dementia.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Editorial Material
Geriatrics & Gerontology
Liang-Kung Chen
AGING MEDICINE AND HEALTHCARE
(2023)
Article
Geriatrics & Gerontology
Chieh Shen, Yi-Chin Lin, Hung-Yu Lin, Liang-Kung Chen, Fei-Yuan Hsiao
Summary: The study examines the impacts of declines in personal mastery on healthy aging among community-dwelling middle-aged and older adults. The findings suggest that declines in personal mastery are associated with declines in self-perceived mobility, but not with other indicators of healthy aging.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Geriatrics & Gerontology
H. -Y. Lin, Y. -C. Lin, L-K Chen, F-Y Hsiao
Summary: Social isolation is closely associated with anorexia and sarcopenia in older adults, significantly exacerbating the long-term mortality risk. While social isolation alone appears to have some mortality risk, the synergistic effects are more pronounced in this study.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Geriatrics & Gerontology
Yi-Chin Lin, Hung-Yu Lin, Liang-Kung Chen, Fei-Yuan Hsiao
Summary: This study examines the associations between subjective aging and the psychological and behavioral responses of older individuals, specifically focusing on the longitudinal changes in biological age. The results indicate that there are no significant associations between changes in biological age and subjective aging across different chronological age groups.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2024)
Article
Geriatrics & Gerontology
Ying-Hsin Hsu, Ming-Yueh Chou, Wei-Cheng Chang, Miao-Ting Chen, Yu-Chun Wang, Mei-Chen Liao, Chih-Kuang Liang, Liang-Kung Chen, Yu-Te Lin
Summary: This study evaluated the association between the change in the number of potentially inappropriate medications (PIMs) in older adults during hospitalization and adverse outcomes. The results showed that increasing PIM use was strongly associated with higher functional decline, prolonged length of stay, and mortality rate. Older adults with three or more PIMs had the greatest risk for adverse outcomes during hospitalization.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2024)
Article
Clinical Neurology
B. -A. Chen, W. -J. Lee, C. -P. Chung, L. -N. Peng, Liang-Kung Chen
Summary: This study found associations between inflammatory biomarkers and cognitive function in healthy middle-aged and older populations. Specifically, higher levels of fibrinogen were negatively associated with cognitive function, particularly in participants aged 65 years or older.
JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE
(2023)
Article
Clinical Neurology
Chih-Ping Chung, Li-Ning Peng, Wei-Ju Lee, Pei-Ning Wang, Ching-Po Lin, Liang-Kung Chen
Summary: The study revealed an association between cerebral small vessel disease (SVD) and Physio-cognitive decline syndrome (PCDS), a phenotype characterized by concurrent physical mobility and cognitive impairments in the non-demented non-disable elderly population.
CEREBRAL CIRCULATION - COGNITION AND BEHAVIOR
(2022)
Article
Geriatrics & Gerontology
W-J Lee, L-N Peng, M-H Lin, C-H Lin, L-K Chen
Summary: The integrated multidomain intervention for community-living older adults with multimorbidity and physio-cognitive decline syndrome (PCDS) has shown significant clinical efficacy in improving cognitive function and quality of life.
JOURNAL OF NUTRITION HEALTH & AGING
(2022)