A Functional Dissection of PTEN N-Terminus: Implications in PTEN Subcellular Targeting and Tumor Suppressor Activity

Yeast-based methods to assess PTEN phosphoinositide phosphatase activity in vivo

(2015) Isabel Rodríguez-Escudero et al.   METHODS

PTENα, a PTEN Isoform Translated through Alternative Initiation, Regulates Mitochondrial Function and Energy Metabolism

(2014) Hui Liang et al.   Cell Metabolism

A new class of cancer-associated PTEN mutations defined by membrane translocation defects

(2014) H-N Nguyen et al.   ONCOGENE

Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities

(2014) Hoai-Nghia Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Unified Nomenclature and Amino Acid Numbering for Human PTEN

(2014) R. Pulido et al.   Science Signaling

When Overgrowth Bumps Into Cancer: The PTEN-Opathies

(2013) JESSICA MESTER et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

PTEN, here, there, everywhere

(2013) C Bassi et al.   CELL DEATH AND DIFFERENTIATION

Diverse Mechanisms of AKT Pathway Activation in Human Malignancy

(2013) Mitchell Cheung et al.   CURRENT CANCER DRUG TARGETS

A Secreted PTEN Phosphatase That Enters Cells to Alter Signaling and Survival

(2013) B. D. Hopkins et al.   SCIENCE

PTEN signaling in autism spectrum disorders

(2012) Jing Zhou et al.   CURRENT OPINION IN NEUROBIOLOGY

Targeting the PI3K signaling pathway in cancer therapy

(2012) Chandra Bartholomeusz et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Tumor Suppressor PTEN Is Exported in Exosomes and Has Phosphatase Activity in Recipient Cells

(2012) U. Putz et al.   Science Signaling

Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner

(2011) Min Sup Song et al.   CELL

Cytoplasmic p27Kip1 counteracts the pro-apoptotic function of the open conformation of PTEN by retention and destabilization of PTEN outside of the nucleus

(2011) Amparo Andrés-Pons et al.   CELLULAR SIGNALLING

A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes

(2011) Isabel Rodríguez-Escudero et al.   HUMAN MOLECULAR GENETICS

Non-genomic loss of PTEN function in cancer: not in my genes

(2011) Nick R. Leslie et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Differential Up-regulation of MAP Kinase Phosphatases MKP3/DUSP6 and DUSP5 by Ets2 and c-Jun Converge in the Control of the Growth ArrestVersusProliferation Response of MCF-7 Breast Cancer Cells to Phorbol Ester

(2010) Caroline E. Nunes-Xavier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mutant form of PTEN linked to autism

(2010) Roberta E. Redfern et al.   PROTEIN SCIENCE

Clinicopathological significance of nuclear PTEN expression in colorectal adenocarcinoma

(2009) Ki-Seok Jang et al.   HISTOPATHOLOGY

Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function

(2009) Glenn P. Lobo et al.   HUMAN MOLECULAR GENETICS

PTEN inhibits BMI1 function independently of its phosphatase activity

(2009) Catherine Fan et al.   Molecular Cancer

PTEN Phosphatase Selectively Binds Phosphoinositides and Undergoes Structural Changes†

(2008) Roberta E. Redfern et al.   BIOCHEMISTRY

The nuclear affairs of PTEN

(2008) S. M. Planchon et al.   JOURNAL OF CELL SCIENCE

JunB Breakdown in Mid-/Late G2 Is Required for Down-Regulation of Cyclin A2 Levels and Proper Mitosis

(2008) R. Farras et al.   MOLECULAR AND CELLULAR BIOLOGY

PTEN Nuclear Localization Is Regulated by Oxidative Stress and Mediates p53-Dependent Tumor Suppression

(2008) C.-J. Chang et al.   MOLECULAR AND CELLULAR BIOLOGY

The role of PTEN signaling perturbations in cancer and in targeted therapy

(2008) M Keniry et al.   ONCOGENE

Assessment of PTEN tumor suppressor activity in nonmammalian models: the year of the yeast

(2008) V J Cid et al.   ONCOGENE

Class I PI3K in oncogenic cellular transformation

(2008) L Zhao et al.   ONCOGENE

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE

A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN

(2008) M. Rahdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA