The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1)

Autophagy: A double-edged sword in Alzheimer’s disease

(2012) Ying-Tsen Tung et al.   JOURNAL OF BIOSCIENCES

Depletion of GGA1 and GGA3 Mediates Postinjury Elevation of BACE1

(2012) K. R. Walker et al.   JOURNAL OF NEUROSCIENCE

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

(2012) Jeremy H. Herskowitz et al.   MOLECULAR BIOLOGY OF THE CELL

Do GGA Adaptors Bind Internal DXXLL Motifs?

(2012) Balraj Doray et al.   TRAFFIC

The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis

(2011) Jie Zhao et al.   Journal of Neuroinflammation

Decreased expression of GGA3 Protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein

(2011) Claudia Santosa et al.   NEUROBIOLOGY OF DISEASE

VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo

(2010) Xuefeng Ren et al.   EMBO JOURNAL

Ubiquitin Regulates GGA3-mediated Degradation of BACE1

(2010) Eugene L. Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gga2 Mediates Sequential Ubiquitin-independent and Ubiquitin-dependent Steps in the Trafficking of ARN1 from thetrans-Golgi Network to the Vacuole

(2009) Yi Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Down-regulation of Seladin-1 Increases BACE1 Levels and Activity through Enhanced GGA3 Depletion during Apoptosis

(2009) Timo Sarajärvi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Primary support cultures of hippocampal and substantia nigra neurons

(2009) Thomas Fath et al.   Nature Protocols

GGA Autoinhibition Revisited

(2009) Jacob F. Cramer et al.   TRAFFIC

Impact of cholesterol level upon APP and BACE proximity and APP cleavage

(2008) Christine A.F. von Arnim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes

(2008) Robyn A. Sharples et al.   FASEB JOURNAL