cir-ITCH Plays an Inhibitory Role in Colorectal Cancer by Regulating the Wnt/β-Catenin Pathway

A novelent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/β-catenin signaling

(2015) Qi Ye et al.   CARCINOGENESIS

Identification of chimeric TSNAX–DISC1 resulting from intergenic splicing in endometrial carcinoma through high-throughput RNA sequencing

(2014) Na Li et al.   CARCINOGENESIS

Increased Levels of the Long Intergenic Non–Protein Coding RNA POU3F3 Promote DNA Methylation in Esophageal Squamous Cell Carcinoma Cells

(2014) Wei Li et al.   GASTROENTEROLOGY

Identification of MicroRNA-214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression

(2014) Dong-liang Chen et al.   HEPATOLOGY

LincRNA-uc002yug.2 involves in alternative splicing of RUNX1 and serves as a predictor for esophageal cancer and prognosis

(2014) H Wu et al.   ONCOGENE

A genetic polymorphism in lincRNA-uc003opf.1 is associated with susceptibility to esophageal squamous cell carcinoma in Chinese populations

(2013) Hongchun Wu et al.   CARCINOGENESIS

RETRACTED: Construction of circular miRNA sponges targeting miR-21 or miR-221 and demonstration of their excellent anticancer effects on malignant melanoma cells

(2013) Yuchen Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Colorectal cancer

(2013) Hermann Brenner et al.   LANCET

Functional polymorphisms in theCD44gene and acute myeloid leukemia cancer risk in a Chinese population

(2013) Hongchun Wu et al.   MOLECULAR CARCINOGENESIS

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

The E3 Ubiquitin Ligase ITCH Negatively Regulates Canonical Wnt Signaling by Targeting Dishevelled Protein

(2012) W. Wei et al.   MOLECULAR AND CELLULAR BIOLOGY

microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis

(2012) N Zhang et al.   ONCOGENE

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

Molecular Genetics of Colorectal Cancer

(2011) Eric R. Fearon   Annual Review of Pathology-Mechanisms of Disease

MicroRNA Signatures: Novel Biomarker for Colorectal Cancer?

(2011) X. Luo et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA

(2011) Thomas B Hansen et al.   EMBO JOURNAL

Transcriptome-wide discovery of circular RNAs in Archaea

(2011) Miri Danan et al.   NUCLEIC ACIDS RESEARCH

MDM2 promotes the proteasomal degradation of p73 through the interaction with Itch in HeLa cells

(2010) Natsumi Kubo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Insights into How RNase R Degrades Structured RNA: Analysis of the Nuclease Domain

(2009) Helen A. Vincent et al.   JOURNAL OF MOLECULAR BIOLOGY

Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation

(2008) D. Sampath et al.   BLOOD

Itch: a HECT-type E3 ligase regulating immunity, skin and cancer

(2008) G Melino et al.   CELL DEATH AND DIFFERENTIATION

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

AIP4/Itch Regulates Notch Receptor Degradation in the Absence of Ligand

(2008) Patricia Chastagner et al.   PLoS One