MAGE-A Cancer/Testis Antigens Inhibit MDM2 Ubiquitylation Function and Promote Increased Levels of MDM4

Identification of MAGEA antigens as causal players in the development of tamoxifen-resistant breast cancer

(2014) P-P Wong et al.   ONCOGENE

The role of ubiquitin modification in the regulation of p53

(2013) Andreas K. Hock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MAGE-A antigens as targets in tumour therapy

(2012) David W. Meek et al.   CANCER LETTERS

MDM4 is a key therapeutic target in cutaneous melanoma

(2012) Agnieszka Gembarska et al.   NATURE MEDICINE

BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death

(2011) Mark Wade et al.   CELL CYCLE

MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs

(2011) L Y Peche et al.   CELL DEATH AND DIFFERENTIATION

MAGE-A Inhibits Apoptosis in Proliferating Myeloma Cells through Repression of Bax and Maintenance of Survivin

(2011) T. Nardiello et al.   CLINICAL CANCER RESEARCH

MdmX Protein Is Essential for Mdm2 Protein-mediated p53 Polyubiquitination

(2011) Xinjiang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MAGE I Transcription Factors Regulate KAP1 and KRAB Domain Zinc Finger Transcription Factor Mediated Gene Repression

(2011) Tony Z. Xiao et al.   PLoS One

Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability

(2011) V. Pant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo

(2011) L. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

When MAGE meets RING: insights into biological functions of MAGE proteins

(2011) Yue Feng et al.   Protein & Cell

Melanoma-associated antigen genes – An update

(2010) Meixiang Sang et al.   CANCER LETTERS

Mage-A Cancer/Testis Antigens Inhibit p53 Function by Blocking Its Interaction with Chromatin

(2010) L. Marcar et al.   CANCER RESEARCH

Transcriptional Synergy between Melanoma Antigen Gene Protein-A11 (MAGE-11) and p300 in Androgen Receptor Signaling

(2010) Emily B. Askew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Comparison of the RING Domains of Two p53 E3 Ligases, Mdm2 and Pirh2

(2010) Jonathan Shloush et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

aMAGEing New Players Enter the RING to Promote Ubiquitylation

(2010) Kristen C. Espantman et al.   MOLECULAR CELL

MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

(2010) Jennifer M. Doyle et al.   MOLECULAR CELL

Translating p53 into the clinic

(2010) Chit Fang Cheok et al.   Nature Reviews Clinical Oncology

Mdm2 facilitates the association of p53 with the proteasome

(2010) R. Kulikov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histological evaluation of AMPK signalling in primary breast cancer

(2009) Sirwan M Hadad et al.   BMC CANCER

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Melanoma Antigen Gene Protein-A11 (MAGE-11) F-box Links the Androgen Receptor NH2-terminal Transactivation Domain to p160 Coactivators

(2009) Emily B. Askew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Melanoma-Associated Antigen A3 Mediates Fibronectin-Controlled Cancer Progression and Metastasis

(2008) W. Liu et al.   CANCER RESEARCH

Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans

(2008) K Linke et al.   CELL DEATH AND DIFFERENTIATION

Mdm2 and Mdm4 Loss Regulates Distinct p53 Activities

(2008) J. A. Barboza et al.   MOLECULAR CANCER RESEARCH