Article
Dentistry, Oral Surgery & Medicine
Minsu Kwon, Yu-Jin Jeong, Jiwon Kwak, Kwang-Yoon Jung, Seung-Kuk Baek
Summary: This study found that good oral health-related behavior was associated with a more frequent history of thyroid disease. Higher CPI values showed a significant association with TFT abnormalities, but the significance decreased after adjusting for other variables like age and sex.
Article
Medicine, Research & Experimental
Davide Pietropaoli, Serena Altamura, Eleonora Ortu, Luca Guerrini, Theresa T. Pizarro, Claudio Ferri, Rita Del Pinto
Summary: This study used data from the third National Health and Nutrition Examination Survey (NHANES III) to analyze the relationship between multiple metabolic syndrome (MetS) components and periodontal diseases. The results showed that MetS components were associated with gingival bleeding but not with periodontitis. This association was observed only in women and not in men.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Yuji Shimizu, Shin-Ya Kawashiri, Yuko Noguchi, Yasuhiro Nagata, Takahiro Maeda, Naomi Hayashida
Summary: Thyroid cysts are associated with hypertension, especially in participants without atherosclerosis. However, there is a significant negative association in individuals with atherosclerosis. This suggests that thyroid cysts have clinical implications by supporting thyroid hormone activity.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Julie A. Pasco, Amanda L. Stuart, Sophia X. Sui, Kara L. Holloway-Kew, Natalie K. Hyde, Monica C. Tembo, Pamela Rufus-Membere, Mark A. Kotowicz, Lana J. Williams
Summary: This study found a cross-sectional relationship between lower limb muscle strength and global cognitive function, indicating an association between low strength of hip abductors and low cognition. The results suggest that poor muscle function may contribute to cognitive decline, emphasizing the importance of muscle strength in cognitive function and warranting further investigation.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Nutrition & Dietetics
Adele Bossel, Gerard Waeber, Antoine Garnier, Pedro Marques-Vidal, Vanessa Kraege
Summary: There is no association between adherence to the Mediterranean diet and the incidence of type 2 diabetes in a non-Mediterranean population.
Article
Multidisciplinary Sciences
Xiaofeng Wang, Zhe Mo, Guangming Mao, Wenming Zhu, Mingluan Xing, Xueqing Li, Yuanyang Wang, Zhifang Wang, Xiaoming Lou
Summary: This study reveals the impact of geographical region on thyroid abnormalities, with inland areas more prone to hypothyroidism and coastal areas more likely to have thyroid nodules. Both regions had sufficient iodine intake, but with some differences. Binary logistic regression models indicated that coastal participants were at a higher risk of thyroid abnormalities.
SCIENTIFIC REPORTS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Piero Papi, Nicola Pranno, Bianca Di Murro, Giorgio Pompa, Antonella Polimeni, Claudio Letizia, Luigi Petramala, Antonio Concistre, Eva Munoz Aguilera, Marco Orlandi, Francesco D'Aiuto
Summary: This cross-sectional study investigated the association between carotid intima-media thickness (c-IMT) values and periodontal and peri-implant diseases in patients with hypertension. The study found a positive association between mucosal/gingival inflammation and subclinical atherosclerosis, as well as the presence of carotid plaque. These associations were independent of traditional cardiovascular risk factors.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Endocrinology & Metabolism
Yutong Han, Chuyuan Wang, Lihui Zhang, Jun Zhu, Mei Zhu, Yongze Li, Di Teng, Weiping Teng, Zhongyan Shan
Summary: This study found a relationship between thyroid dysfunction and dyslipidemia, particularly with hypertriglyceridemia and low high-density lipoprotein cholesterol. Hypothyroidism was associated with an increased risk of dyslipidemia in menopausal females, while hyperthyroidism was associated with a reduced risk of dyslipidemia in premenopausal females.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Yanshi Ye, Ye Li, Qintao Ma, Ying Li, Huixian Zeng, Yaosheng Luo, Yongqian Liang, Lan Liu, Lingling Liu, Xu Lin, Genfeng Yu, Cheng Song, Heng Wan, Jie Shen
Summary: This study investigated the association between thyroid function and other elements. It found that copper and zinc levels were related to thyroid stimulating hormone (TSH) levels, iron and copper levels were associated with free triiodothyronine (FT3) and free thyroxine (FT4) levels respectively, and manganese was negatively correlated with thyrotropin T4 resistance index (TT4RI) while zinc was positively correlated. It suggests that patients with thyroid disorders should measure these important elements.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Oncology
Nadia Bouzehouane, Pascal Roy, Myriam Decaussin-Petrucci, Mireille Bertholon-Gregoire, Chantal Bully, Agnes Perrin, Helene Lasolle, Jean-Christophe Lifante, Francoise Borson-Chazot, Claire Bournaud
Summary: This study assessed the risk of reduced disease-free survival (DFS) and poor clinical outcome in patients with papillary thyroid carcinomas (PTC) with microscopic extra-thyroidal extension (mETE), as compared to PTC patients without mETE. The results suggest that mETE is an independent poor prognosis factor of reduced DFS and predictive of poor clinical outcome.
Article
Endocrinology & Metabolism
Shumi Ji, Xiaoyan Wu, Jiani Wu, Diqun Chen, Zhihui Chen
Summary: This study aimed to assess the relationship between serum iodine concentration (SIC) and urinary iodine concentration (UIC), dietary iodine, thyroid function, and thyroid diseases in pregnant women in the southeast coast of China, and to provide a normal reference range of SIC for pregnant women.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Immunology
Tianyu Zhang, Feifei Hou, Dan Liu, Hangfan Zhou, Yutong Sun, Xiaoting Deng, Yiming Xu, Yanxuan Xiao, Xianwen Wang, Chuanji Wu, Yang Meng, Peiyang Yuan, Xuemei Qiu, Lu Ye, Yuye Liang, Wei Wei, Lu Jiang
Summary: This study found that the prevalence of Hashimoto's thyroiditis was higher in patients with oral lichen planus, especially in females. Female patients also had higher levels of auto-anti-thyroid antibodies. However, the clinical manifestations of oral lichen planus were not significantly correlated with the development of Hashimoto's thyroiditis or auto-anti-thyroid antibody levels.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Environmental Sciences
Qi Tian, Danqing Huang
Summary: The study aimed to investigate the association between urinary IPM3 and cardio-cerebrovascular diseases (CVD) in general adults. A total of 1775 participants from the National Health and Nutrition Examination Surveys were enrolled. Urinary levels of IPM3, as a measure of isoprene exposure, were assessed using LC/MS. The results showed a significant increase in the prevalence of CVD across IPM3 quartiles, with the highest quartile associated with a 2.47-fold increased risk of CVD compared to the lowest quartile.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Endocrinology & Metabolism
Diana Borges Duarte, Vania Benido Silva, Guilherme Assuncao, Andre Couto Carvalho, Claudia Freitas
Summary: This study evaluated the incidence of non-thyroidal second primary malignancy (NTSPM) in patients with papillary thyroid cancer (PTC) and found that its incidence was higher compared to the general population. Younger age and a family history of malignancy were associated with an increased risk of developing secondary neoplasia.
EUROPEAN THYROID JOURNAL
(2022)
Article
Endocrinology & Metabolism
Xiaoqian Dong, Ying Li, Jianfei Xie, Lijun Li, Ziyu Wan, Yue Kang, Yating Luo, Jiangang Wang, Yinglong Duan, Siqing Ding, Andy S. K. Cheng
Summary: This study found that women over 50 and those with mainly manual jobs are more likely to have thyroid nodules, while moderate dietary diversity and normal triglycerides levels can reduce the risk of nodules.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Giorgio Grani, Valeria Del Gatto, Vito Cantisani, Susan J. Mandel, Cosimo Durante
Summary: The study aimed to identify gray-scale sonographic features independently associated with malignancy and compare different definitions. The results showed that suspicious lymph node, extrathyroidal extension, irregular or infiltrative margins, marked hypoechogenicity, solid composition, and punctate hyperechoic foci were independent predictors of malignancy, while taller-than-wide shape was not confirmed to be an independent predictor.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Giorgio Grani, Michele Gentili, Federico Siciliano, Domenico Albano, Valentina Zilioli, Silvia Morelli, Efisio Puxeddu, Maria Chiara Zatelli, Irene Gagliardi, Alessandro Piovesan, Alice Nervo, Umberto Crocetti, Michela Massa, Maria Teresa Sama, Chiara Mele, Maurilio Deandrea, Laura Fugazzola, Barbara Puligheddu, Alessandro Antonelli, Ruth Rossetto, Annamaria D'Amore, Graziano Ceresini, Roberto Castello, Erica Solaroli, Marco Centanni, Salvatore Monti, Flavia Magri, Rocco Bruno, Clotilde Sparano, Luciano Pezzullo, Anna Crescenzi, Caterina Mian, Dario Tumino, Andrea Repaci, Maria Grazia Castagna, Vincenzo Triggiani, Tommaso Porcelli, Domenico Meringolo, Laura Locati, Giovanna Spiazzi, Giulia Di Dalmazi, Aris Anagnostopoulos, Stefano Leonardi, Sebastiano Filetti, Cosimo Durante
Summary: Researchers have developed a comprehensive data-driven model to predict recurrent disease in thyroid cancer, utilizing the Italian Thyroid Cancer Observatory database. The decision tree model outperformed the current risk stratification system and can improve the prediction of treatment response. The inclusion of other variables can enhance the accuracy of risk assessment.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
G. Grani, L. Lamartina, T. Montesano, M. Maranghi, S. Filetti, C. Durante, S. Lopatriello
Summary: Ultrasound screening for thyroid cancer is not cost-effective for asymptomatic adults, and there is less consensus on screening for high-risk individuals. This study aimed to estimate the costs of ultrasound screening for individuals with a family history of thyroid cancer.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Review
Medicine, General & Internal
Federica Gagliardi, Enke Baldini, Eleonora Lori, Silvia Cardarelli, Daniele Pironi, Augusto Lauro, Domenico Tripodi, Piergaspare Palumbo, Eleonora D'Armiento, Giuseppe Cavallaro, Andrea Polistena, Valerio D'Orazi, Simone Sibio, Poupak Fallahi, Alessandro Antonelli, Vito D'Andrea, Salvatore Ulisse, Salvatore Sorrenti
Summary: Benign and malignant thyroid diseases are linked to the occurrence of extrathyroidal malignancies, including colorectal cancers. Understanding the relationship between these diseases can provide insights into their etiology and/or progression, as well as potential shared genetic and environmental factors. Exploring the underlying molecular mechanisms can lead to improved clinical management and increased surveillance for patients with thyroid diseases at a higher risk of developing extrathyroidal malignancies.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Vincenzo Dolcetti, Eleonora Lori, Daniele Fresilli, Giovanni Del Gaudio, Chiara Di Bella, Patrizia Pacini, Vito D'Andrea, Fabrizio Maria Frattaroli, Giulia Giordana Vallone, Piero Liberatore, Daniele Pironi, Gian Luigi Canu, Pietro Giorgio Calo, Vito Cantisani, Salvatore Sorrenti
Summary: To reduce bleeding-related morbidity in thyroid surgery, new techniques and devices for controlling bleeding have been introduced. The study aimed to describe the ultrasound appearance of topical hemostatics in patients undergoing thyroidectomy. The study evaluated the advantages and disadvantages of different hemostatic agents, including oxidized regenerated cellulose and fibrin glue.
Editorial Material
Oncology
Salvatore Sorrenti, Pietro Giorgio Calo
Article
Endocrinology & Metabolism
Simone De Leo, Silvia D'Elia, Giorgio Grani, Francesco Dondi, Francesco Bertagna, Efisio Puxeddu, Silvia Morelli, Alessandro Piovesan, Alice Nervo, Maria Chiara Zatelli, Irene Gagliardi, Maria Teresa Sama, Gianluca Aimaretti, Umberto Crocetti, Michela Massa, Maurilio Deandrea, Francesca Retta, Loredana Pagano, Mattia Rossi, Erica Solaroli, Luciano Pezzullo, Maria Grazia Chiofalo, Alfredo Pontecorvi, Celestino Pio Lombardi, Alessandro Antonelli, Armando Patrizio, Ilaria Messuti, Flavia Magri, Giovanna Spiazzi, Graziano Ceresini, Rocco Bruno, Clotilde Sparano, Marco Centanni, Anna Crescenzi, Giovanni Tallini, Vincenzo Marotta, Bruno Madeo, Caterina Mian, Sebastiano Filetti, Cosimo Durante, Laura Fugazzola
Summary: This study examined the relationship between autoimmune thyroiditis (AT) and 1-year treatment outcomes in patients with differentiated thyroid cancer (DTC). The findings suggest that AT may be associated with higher biochemical persistence at 1-year follow-up.
Article
Nutrition & Dietetics
Vincenzo Spina, Enke Baldini, Silvia Cardarelli, Cosimo Oliva, Stefano Venarubea, Franca Faraoni, Giovanni Pastore, Rachele Tittoni, Angela Musella, Antonia Squarcella, Eleonora Lori, Elisabetta Renzi, Roberta Feroci, Flavia Mastrodonato, Fabiola Ciferri, Camilla Virili, Marco Centanni, Cristina Fabiani, Rocco Rago, Michele Carlo Schiavi, Pierluigi Palazzetti, Eleonora D'Armiento, Vito Cantisani, Salvatore Sorrenti, Salvatore Ulisse
Summary: Adequate iodine intake is crucial in pregnancy, and pregnant women and their fetuses are still exposed to iodine deficiency. The consumption of iodine-containing supplements should be recommended in pregnancy.
Article
Medicine, General & Internal
Angela Gurrado, Alessandro Pasculli, Nicola Avenia, Rocco Bellantone, Marco Boniardi, Isabella Merante Boschin, Pietro Giorgio Calo, Michele Camandona, Giuseppe Cavallaro, Fabio Cianchi, Giovanni Conzo, Vito D'Andrea, Carmela De Crea, Loredana De Pasquale, Paolo Del Rio, Giovanna Di Meo, Gianlorenzo Dionigi, Chiara Dobrinja, Giovanni Docimo, Fausto Fama, Attilio Galimberti, Laura Giacomelli, Giuseppa Graceffa, Maurizio Iacobone, Nadia Innaro, Celestino Pio Lombardi, Gabriele Materazzi, Fabio Medas, Barbara Mullineris, Luigi Oragano, Nicola Palestini, Giuliano Perigli, Angela Pezzolla, Francesco Paolo Prete, Marco Raffaelli, Giuseppina Renzulli, Lodovico Rosato, Gregorio Scerrino, Lucia Ilaria Sgaramella, Salvatore Sorrenti, Carlotta Testini, Massimiliano Veroux, Guido Gasparri, Mario Testini
Summary: This multicenter study aimed to describe the clinical characteristics and differentiate parathyroid cancer (PC) from atypical parathyroid tumour (APT). The study found significant differences between PC and APT in terms of bone involvement, abdominal and neurological symptoms, and ultrasound diameter.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Noemi Zorzetti, Augusto Lauro, Manuela Cuoghi, Marco La Gatta, Ignazio R. Marino, Salvatore Sorrenti, Vito DAndrea, Andrea Mingoli, Giuseppe Giovanni Navarra
Summary: This article introduces the use of ICG-FA in evaluating patients with acute appendicitis undergoing laparoscopic appendectomy. This new method provides intraoperative information on tissue and organ perfusion, guiding surgical decisions and techniques.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Gian Luigi Canu, Federico Cappellacci, Ahmed Abdallah, Islam Elzahaby, David Figueroa-Bohorquez, Eleonora Lori, Julie A. Miller, Sergio Zuniga Pavia, Pilar Pinillos, Atcharaporn Pongtippan, Saleh Saleh Saleh, Salvatore Sorrenti, Chutintorn Sriphrapradang, Pietro Giorgio Calo, Fabio Medas
Summary: This study evaluated the management of indeterminate thyroid nodules across different regions, finding that the Asian region leans towards active surveillance while Eastern regions have a more aggressive approach. Current clinical practice diverges from guidelines, particularly regarding fine-needle aspiration cytology indications. The study highlights the need for homogenous guidelines and new tools to assess the actual risk of malignancy in patients with indeterminate thyroid nodules.
Article
Medicine, General & Internal
Chiara Scorziello, Maria Carola Borcea, Marco Biffoni, Angelina Pernazza, Francesca Arienzo, Rossella Melcarne, Luca Ventrone, Angelo Laca, Giorgio Grani, Cosimo Durante, Fabrizio Consorti, Laura Giacomelli
Summary: Incidental sonographic discovery of thyroid nodules is common in clinical practice. Suspicious cervical lymph nodes may be detected in patients with cytological benign thyroid nodules. We discuss a case of cervical lymph node metastasis from a lung carcinoma in a 65-year-old asymptomatic male smoker. Differentiating metastatic lesions in the thyroid gland can be challenging, especially when evaluating lesions in the region and when fine needle aspiration biopsy yields negative results or cytological evaluations are inconsistent with thyroid cytological findings and sonographic features. Detecting lung cancer at earlier stages remains a clinical challenge, as it is the leading cause of cancer mortality worldwide.
CLINICAL CASE REPORTS
(2023)
Review
Endocrinology & Metabolism
Elisa Acitelli, Carlo Maiorca, Giorgio Grani, Marianna Maranghi
Summary: Multitargeted kinase inhibitors (MKIs) are widely used in cancer treatment and have shown significant efficacy in improving survival. However, they can also cause important side effects, including arterial hypertension, mucositis, and skin lesions. We conducted a review to specifically evaluate the effects of MKIs on glucose and lipid metabolism.