Endogenous Interferon-β-Inducible Gene Expression and Interferon-β-Treatment Are Associated with Reduced T Cell Responses to Myelin Basic Protein in Multiple Sclerosis

Serum IL-17F does not predict poor response to IM IFN -1a in relapsing-remitting MS

(2012) S. E. Bushnell et al.   NEUROLOGY

Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease

(2011) Wenjun Ouyang et al.   Annual Review of Immunology

IL-27 mediates the response to IFN-β therapy in multiple sclerosis patients by inhibiting Th17 cells

(2011) Cheryl M. Sweeney et al.   BRAIN BEHAVIOR AND IMMUNITY

The Mechanism of Action of Interferon-β in Relapsing Multiple Sclerosis

(2011) Bernd C. Kieseier   CNS DRUGS

Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity

(2011) Xin Chen et al.   FEBS LETTERS

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

Interferon-β exacerbates Th17-mediated inflammatory disease

(2011) Robert C. Axtell et al.   TRENDS IN IMMUNOLOGY

Clinical Effect of Neutralizing Antibodies to Interferon Beta That Persist Long After Cessation of Therapy for Multiple Sclerosis

(2010) Laura F. van der Voort   ARCHIVES OF NEUROLOGY

Th1 versus Th17: Are T cell cytokines relevant in multiple sclerosis?

(2010) Amy E. Lovett-Racke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Biology of interleukin-10

(2010) Robert Sabat et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Disease protection and interleukin-10 induction by endogenous interferon-β in multiple sclerosis?

(2010) D. Hesse et al.   EUROPEAN JOURNAL OF NEUROLOGY

Interferon-β is a key regulator of proinflammatory events in experimental autoimmune encephalomyelitis

(2010) CL Galligan et al.   Multiple Sclerosis Journal

Programmed death-1–induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

(2010) Elias A Said et al.   NATURE MEDICINE

Breakthrough disease during interferon-  therapy in MS: No signs of impaired biologic response

(2010) D. Hesse et al.   NEUROLOGY

Spontaneous MxA mRNA level predicts relapses in patients with recently diagnosed MS

(2010) L. F. van der Voort et al.   NEUROLOGY

The challenge of multiple sclerosis: How do we cure a chronic heterogeneous disease?

(2009) Howard L. Weiner   ANNALS OF NEUROLOGY

A type I interferon signature in monocytes is associated with poor response to interferon-β in multiple sclerosis

(2009) M. Comabella et al.   BRAIN

Identification of new sensitive biomarkers for thein vivoresponse to interferon-β treatment in multiple sclerosis using DNA-array evaluation

(2009) F. Sellebjerg et al.   EUROPEAN JOURNAL OF NEUROLOGY

Sequential Polarization and Imprinting of Type 1 T Helper Lymphocytes by Interferon-γ and Interleukin-12

(2009) Edda G. Schulz et al.   IMMUNITY

The self-antigen, thyroglobulin, induces antigen-experienced CD4+T cells from healthy donors to proliferate and promote production of the regulatory cytokine, interleukin-10, by monocytes

(2009) Claus H. Nielsen et al.   IMMUNOLOGY

IFN-  Inhibits Human Th17 Cell Differentiation

(2009) V. S. Ramgolam et al.   JOURNAL OF IMMUNOLOGY

The effect of β-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis

(2008) Chris J. Hedegaard et al.   CLINICAL IMMUNOLOGY

Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

(2008) Marco Prinz et al.   IMMUNITY

T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis

(2008) Chris J. Hedegaard et al.   IMMUNOLOGY

The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice

(2008) Beichu Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

IFN-β-regulated genes show abnormal expression in therapy-naïve relapsing–remitting MS mononuclear cells: Gene expression analysis employing all reported protein–protein interactions

(2008) Ken D. Yamaguchi et al.   JOURNAL OF NEUROIMMUNOLOGY

Increased IL-10 mRNA and IL-23 mRNA expression in multiple sclerosis: interferon-β treatment increases IL-10 mRNA expression while reducing IL-23 mRNA expression

(2008) M Krakauer et al.   Multiple Sclerosis Journal