Article
Veterinary Sciences
Juan Pablo Villanueva-Cabezas, Karma Rinzin, Sithar Dorjee, Pema Tshewang, Ugyen Namgyel, Puspa Maya Sharma, Mark A. Stevenson, Jodie McVernon
Summary: The study investigates veterinary antibiotic prescriptions in Bhutan, showing positive features of antimicrobial stewardship. However, it highlights the need for close monitoring of antibiotic prescriptions for key species and further improvements in antibiotic stewardship practices.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Integrative & Complementary Medicine
Ann-Kathrin Lederer, Yvonne Samstag, Thomas Simmet, Tatiana Syrovets, Roman Huber
Summary: This study investigates the usage of complementary medicine (CM) among surgical patients in Germany and finds a high percentage of CM users with a strong interest in CM. However, communication about CM between patients and surgeons is lacking.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2022)
Article
Health Care Sciences & Services
Yang Wang, Tailai Wu, Zhuo Chen
Summary: This study examines the antecedents of active usage of mobile health applications by categorizing attributes into three categories and analyzing the impact of consumer satisfaction and dissatisfaction. The results show that excitement attributes and performance attributes positively influence consumer satisfaction, while performance attributes and basic attributes negatively impact consumer dissatisfaction.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Infectious Diseases
Marianne Moerer, Roswitha Merle, Wolfgang Baeumer
Summary: The amendment to regulations of veterinary pharmacies in Germany has had a positive impact on the use of antibiotics in dogs and cats. The results of an online survey showed a decrease in the use of highest priority critically important antimicrobials and overall antimicrobial use. Veterinarians are requesting antimicrobial susceptibility testing more frequently and opting for alternative antimicrobials in treatment.
Article
Microbiology
Aida Bianco, Francesca Licata, Alessandro Trovato, Francesco Napolitano, Maria Pavia
Summary: The study found that despite 93.7% of Italian community pharmacists knowing that DAwP is illegal, about 37.1% claimed to be involved in this practice. Most pharmacists reported always/often asking clients about drug allergies and medication history, with 66.2% warning clients about potential drug side effects and 55% informing them about the importance of completing the full course of antibiotics.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Urban Studies
Xiao Qin, Feng Zhen, Shanqi Zhang
Summary: The study found that the degree of urbanization of housing location, housing type, and number of rooms are positively associated with the duration of tele-services, telecommuting, and general ICT usage, but negatively associated with the duration of tele-leisure.
Article
Infectious Diseases
Pendo M. Ndaki, Martha F. Mushi, Joseph R. Mwanga, Eveline T. Konje, Nyanda E. Ntinginya, Blandina T. Mmbaga, Katherine Keenan, Wilber Sabiiti, Mike Kesby, Fernando Benitez-Paez, Alison Sandeman, Matthew T. G. Holden, Stephen E. Mshana
Summary: The study revealed a high prevalence of dispensing amoxicillin without prescription in pharmacies and drug dispensing outlets across three regions in Tanzania. Despite existing laws and regulations prohibiting this practice, there is non-compliance by drug providers, highlighting the need for enforcement, surveillance, and education on dispensing practices.
Article
Veterinary Sciences
Cecilie Liv Nielsen, Mogens Agerbo Krogh, Jan Tind Sorensen, Hanne Kongsted
Summary: The study found that cross-fostering increases antibiotic usage in piglets during the nursing period and tends to affect the clinical health at weaning negatively.
PREVENTIVE VETERINARY MEDICINE
(2022)
Article
Infectious Diseases
Sien De Koster, Moniek Ringenier, Christine Lammens, Arjan Stegeman, Tijs Tobias, Francisca Velkers, Hans Vernooij, Marjolein Kluytmans-van den Bergh, Jan Kluytmans, Jeroen Dewulf, Herman Goossens
Summary: This study found marked differences in antibiotic resistance between countries, farms, and within farms in Belgium and the Netherlands. ESBL-E. coli were more prevalent in Belgian samples, while CiproR-E. coli were highly prevalent in broilers of both countries. Multidrug resistance was frequently observed in samples from both countries, with a higher prevalence of ESBL production in combination with ciprofloxacin resistance in samples from Belgium.
Article
Psychiatry
Moudi M. Alasmari, Raghad S. Alkanani, Asmaa S. Alshareef, Shahd S. Alsulmi, Reuof I. Althegfi, Teef A. Bokhari, Mona Y. Alsheikh, Heba K. Alshaeri
Summary: The prevalence of sleeping pill misuse is high among medical students, particularly among those in preclinical years. The most common misuse behavior is self-prescription. Factors associated with sleeping pill misuse include stimulant usage, higher grade point average, preclinical years, and longer average time required to fall asleep. Therefore, raising awareness about the dangers of sleeping pill misuse is crucial.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Infectious Diseases
Atsadaporn Niyomyart, Susan Ka Yee Chow, Wunwisa Bualoy, Nipaporn Butsing, Xingjuan Tao, Xuejiao Zhu
Summary: This study aimed to investigate the antibiotic knowledge, antibiotic resistance knowledge, and antibiotic use among adults in Bangkok, Thailand. A sample of 161 individuals living in Bangkok completed an online questionnaire. The results showed that more than half of the respondents had misconceptions about the effectiveness of antibiotics for treating colds and flu. Additionally, education level and profession were associated with better knowledge in antibiotics and antibiotic resistance respectively.
Article
Dermatology
A. C. Pilz, V Durner, M. C. Schielein, B. Schuster, J. Beckmann, T. Biedermann, K. Eyerich, A. Zink
Summary: This study found elevated positive screening rates for problematic alcohol consumption, drug use disorders, Internet addiction, and problem gambling among adult AD patients compared to the general population. The co-occurrences of different addictions and a positive correlation between smoking and DLQI scores were observed in the study. Screening for addictions routinely may improve patient-centred health care for AD patients.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2022)
Article
Health Care Sciences & Services
Marvin Kopka, Lennart Scatturin, Hendrik Napierala, Daniel Fuerstenau, Markus A. Feufel, Felix Balzer, Malte L. Schmieding
Summary: The usage of symptom checkers in Germany is mainly among females, younger individuals, and those with higher education levels. These apps are perceived as useful by users, but not all who are aware of them use them. Therefore, it is necessary to design symptom checkers that cater to specific user needs and develop strategies to help individuals who are unaware of them yet.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Infectious Diseases
Mohamed A. Hussain, Ahmed O. Mohamed, Omalhassan A. Abdelkarim, Bashir A. Yousef, Asma A. Babikir, Maysoon M. Mirghani, Entsar A. Mohamed, Wadah Osman, Ramzi A. Mothana, Rashid Elhag
Summary: This study aimed to estimate the prevalence and predictors of self-medication with antibiotics (SMA) in Sudan. The results showed that out of 1492 participants surveyed, 71.3% used antibiotics as self-medication. Non-insured and low level of education participants were more likely to predict SMA.
Article
Public, Environmental & Occupational Health
Vera Kluender, Paula Schwenke, Elke Hertig, Carmen Jochem, Irena Kaspar-Ott, Eva-Maria Schwienhorst-Stich, Lisa Stauch, Michaela Coenen
Summary: Planetary Health education is gaining attention in health-related disciplines, and this study aimed to assess students' knowledge of and interest in this field. The majority of surveyed students showed limited prior knowledge of Planetary Health but expressed interest in learning more. They also considered Planetary Health relevant to their fields of study and expressed willingness to choose a Planetary Health elective. Students showed particular interest in topics related to climate and health, mental health, and (micro) plastics.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Cell Biology
Ann Kristin Barton, Ina-Gabriele Richter, Tanja Ahrens, Roswitha Merle, Abdollah Alalwani, Svenja Lilge, Katrin Purschke, Dirk Barnewitz, Heidrun Gehlen
Summary: The study aimed to compare sepsis scoring with the concentrations of MMPs and inflammatory chemokines in equine colic patients. MMP-9 was found to be a biomarker with high diagnostic value for sepsis, with a concentration of >113 ng/ml in peritoneal fluid being an ideal cutoff for positive sepsis scoring.
MEDIATORS OF INFLAMMATION
(2021)
Article
Multidisciplinary Sciences
Beneditta Suwono, Tim Eckmanns, Heike Kaspar, Roswitha Merle, Benedikt Zacher, Chris Kollas, Armin A. Weiser, Ines Noll, Marcel Feig, Bernd-Alois Tenhagen
Summary: This study conducts a comparative analysis of resistance combinations in Escherichia coli from human and different animal populations in Germany, finding similarities in resistance frequencies between clinical isolates from humans and animals, as well as healthy poultry isolates. Cluster analysis demonstrates a linkage between human and various animal isolates based on resistance combinations, supporting a potential one-health approach for antibiotic resistance in Germany.
Article
Agriculture, Dairy & Animal Science
Gudrun Haase, Mechthild Wiegard, Christa Thoene-Reineke, Katrin Baumgartner, Lorenzo von Fersen, Hermann Will, Roswitha Merle, Manel Lopez-Bejar, Oriol Tallo-Parra, Annais Carbajal, Lukas Reese
Summary: The flight restriction of great white pelicans does not seem to have a significant impact on welfare indicators, adrenal activity, or behavior assessed in this study. However, reversibly deflighted pelicans showed higher levels of stress indicator CORTf compared to irreversibly deflighted and airworthy pelicans. Additionally, group size of the pelicans may influence their welfare, with larger groups having lower stress levels.
Article
Multidisciplinary Sciences
Andreas W. Oehm, Roswitha Merle, Annegret Tautenhahn, K. Charlotte Jensen, Kerstin-Elisabeth Mueller, Melanie Feist, Yury Zablotski
Summary: Lameness is a significant issue in intensively managed dairy herds globally, with negative impacts on animal welfare and economic viability. Factors such as low body condition, elevated somatic cell count, severe hock lesions, increasing parity, absence of pasture access, and poor udder cleanliness are associated with higher locomotion scores. Additionally, breed, observer, and season also influence locomotion scores. The use of locomotion scores instead of a dichotomised response variable provides a more detailed understanding of the complex nature of gait disturbances in dairy cows.
Article
Agriculture, Dairy & Animal Science
Marielu Voit, Katrin Baumgartner, Lorenzo von Fersen, Roswitha Merle, Lukas Reese, Mechthild Wiegard, Hermann Will, Oriol Tallo-Parra, Annais Carbajal, Manel Lopez-Bejar, Christa Thoene-Reineke
Summary: The study compared two methods, plucking and cutting feathers, for determining corticosterone levels in feathers. Results showed no significant differences in corticosterone levels between the two methods for both species, indicating that cutting feathers is a valid alternative sampling method.
Article
Agriculture, Dairy & Animal Science
Melanie Humpenoeder, Giuliano M. Corte, Marcel Pfuetzner, Mechthild Wiegard, Roswitha Merle, Katharina Hohlbaum, Nancy A. Erickson, Johanna Plendl, Christa Thoene-Reineke
Summary: The study on simulators in laboratory animal science education and training found strong support for their use as a useful supplement, but concluded that current simulators may not fully replace live animal training. Further research and development are needed to ensure more realistic and comprehensive protection of laboratory animals in education and training.
Article
Agriculture, Dairy & Animal Science
Jakob Hoevener, Julie Pokar, Roswitha Merle, Heidrun Gehlen
Summary: In this study, cardiac auscultation was found to be effective in identifying the affected valve in warmblood horses, but less accurate in determining the grade of regurgitation. The loudness of the murmur was found to be associated with the grade of regurgitation, while dimensional changes were typically linked to more severe regurgitations and higher-grade murmurs.
Article
Infectious Diseases
Marianne Moerer, Roswitha Merle, Wolfgang Baeumer
Summary: The amendment to regulations of veterinary pharmacies in Germany has had a positive impact on the use of antibiotics in dogs and cats. The results of an online survey showed a decrease in the use of highest priority critically important antimicrobials and overall antimicrobial use. Veterinarians are requesting antimicrobial susceptibility testing more frequently and opting for alternative antimicrobials in treatment.
Article
Chemistry, Multidisciplinary
Nina Langkabel, Verena Oswaldi, Roswitha Merle, Janine Dzierzon, Diana Meemken
Summary: The objective of this study was to determine the effect of freezing broiler neck skin samples on their microbial analysis. The results showed that there was no significant difference between frozen and fresh samples in terms of total viable count and Enterobacteriaceae count. Therefore, freezing broiler neck skin samples can be considered as a viable option for microbiological examination.
APPLIED SCIENCES-BASEL
(2022)
Article
Agriculture, Dairy & Animal Science
Dagmar S. Trachsel, Hannah J. Stage, Sebastian Rausch, Susanne Trappe, Katharina Sollig, Gerhard Sponder, Roswitha Merle, Jorg R. Aschenbach, Heidrun Gehlen
Summary: This study explores the potential of adipose tissue-derived stem cells in the differentiation into heart cells in horses. By comparing different isolation methods from various adipose tissue sources, it was found that abdominal adipose tissue is suitable for isolating equine stem cells. However, unlike in other species, equine stem cells showed resistance to the induction of heart cell differentiation.
Article
Agriculture, Dairy & Animal Science
Sabita Diana Stoeckle, Detlef Timmermann, Roswitha Merle, Heidrun Gehlen
Summary: Laminitic horses commonly suffer from an endocrine disease such as equine metabolic syndrome, with hyperinsulinemia considered a key factor. Resting plasma amino acid concentrations differed significantly between obese horses and those with insulin dysregulation and laminitis, suggesting the potential for diagnostic testing and feed supplements for horses at risk of developing laminitis.
Article
Agriculture, Dairy & Animal Science
Sabita Diana Stoeckle, Detlef Timmermann, Roswitha Merle, Heidrun Gehlen
Summary: Pituitary pars intermedia dysfunction (PPID) is a common disease in aged horses and ponies, involving oxidative damage to dopaminergic pathways. Changes in serum amino acid profiles may be potential diagnostic markers and interesting research approaches in PPID, similar to Parkinson's disease in humans.
Article
Veterinary Sciences
Heidrun Gehlen, Katja-Sophia Klein, Roswitha Merle, Antina Luebke-Becker, Sabita D. Stoeckle
Summary: The role of indicator pathogens in equine surgical site infection (SSI) and other infection-promoting factors was evaluated through a cross-sectional study. The results showed that MDRPs were identified in almost 70% of the SSI, indicating that colonization with MDR pathogens is only one of the crucial factors for the development of SSI.
VETERINARY MEDICINE AND SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Hannah J. Stage, Susanne Trappe, Katharina Soellig, Dagmar S. Trachsel, Katharina Kirsch, Cornelia Zieger, Roswitha Merle, Joerg R. Aschenbach, Heidrun Gehlen
Summary: This study investigated the proliferation and multilineage differentiation potential of equine adipose stem cells (ASCs) obtained from different tissue sources. The study found that ASCs had high proliferation and differentiation potential, but were unable to undergo cardiomyogenic differentiation. This study provides a basis for future research in equine medicine.
Article
Infectious Diseases
Marianne Moerer, Antina Luebke-Becker, Astrid Bethe, Roswitha Merle, Wolfgang Baeumer
Summary: The aim of this study was to investigate the impact of the second amendment to the Regulation of Veterinary Pharmacies (TaHAV) in 2018 on the occurrence of antimicrobial resistance in selected bacterial pathogens isolated from dogs and cats in Germany. The study found that the amendment led to an increase in sample submissions in Germany. The highest resistance rates were found for Staphylococcus pseudintermedius, Staphylococcus aureus, and Escherichia coli, while resistance rates were low for Pasteurella multocida and β-hemolytic streptococci. Significant decreases in resistance rates were observed for S. pseudintermedius against penicillin G and ampicillin, S. felis against amoxicillin-clavulanic acid and cefovecin, and S. aureus against enrofloxacin.