Hook Proteins: Association with Alzheimer Pathology and Regulatory Role of Hook3 in Amyloid Beta Generation

Regional Selectivity of rab5 and rab7 Protein Upregulation in Mild Cognitive Impairment and Alzheimer's Disease

(2017) Stephen D. Ginsberg et al.   JOURNAL OF ALZHEIMERS DISEASE

Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding

(2014) Katharina Flach et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hook is an adapter that coordinates kinesin-3 and dynein cargo attachment on early endosomes

(2014) Ewa Bielska et al.   JOURNAL OF CELL BIOLOGY

Integrated regulation of motor-driven organelle transport by scaffolding proteins

(2014) Meng-meng Fu et al.   TRENDS IN CELL BIOLOGY

Intracellular Itinerary of Internalised β-Secretase, BACE1, and Its Potential Impact on β-Amyloid Peptide Biogenesis

(2013) Pei Zhi Cheryl Chia et al.   TRAFFIC

Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability

(2012) Katharina Flach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MSUT2 is a determinant of susceptibility to tau neurotoxicity

(2011) Chris R. Guthrie et al.   HUMAN MOLECULAR GENETICS

Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression

(2010) Stephen D. Ginsberg et al.   BIOLOGICAL PSYCHIATRY

SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans

(2009) Chris R. Guthrie et al.   HUMAN MOLECULAR GENETICS

Dynein Dysfunction Induces Endocytic Pathology Accompanied by an Increase in Rab GTPases

(2009) Nobuyuki Kimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Murine CENP-F Regulates Centrosomal Microtubule Nucleation and Interacts with Hook2 at the Centrosome

(2009) Katherine L. Moynihan et al.   MOLECULAR BIOLOGY OF THE CELL

Alzheimer's-related endosome dysfunction in Down syndrome is A -independent but requires APP and is reversed by BACE-1 inhibition

(2009) Y. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression

(2008) M. V. Rao et al.   JOURNAL OF NEUROSCIENCE

Loss of LR11/SORLA Enhances Early Pathology in a Mouse Model of Amyloidosis: Evidence for a Proximal Role in Alzheimer's Disease

(2008) S. E. Dodson et al.   JOURNAL OF NEUROSCIENCE

An FTS/Hook/p107FHIP Complex Interacts with and Promotes Endosomal Clustering by the Homotypic Vacuolar Protein Sorting Complex

(2008) Lai Xu et al.   MOLECULAR BIOLOGY OF THE CELL

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A  accumulation

(2008) A. Muhammad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA