Monoclonal Antibody Targeting of Fibroblast Growth Factor Receptor 1c Ameliorates Obesity and Glucose Intolerance via Central Mechanisms
出版年份 2014 全文链接
标题
Monoclonal Antibody Targeting of Fibroblast Growth Factor Receptor 1c Ameliorates Obesity and Glucose Intolerance via Central Mechanisms
作者
关键词
-
出版物
PLoS One
Volume 9, Issue 11, Pages e112109
出版商
Public Library of Science (PLoS)
发表日期
2014-11-27
DOI
10.1371/journal.pone.0112109
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Hypothalamic Tanycytes Are an ERK-Gated Conduit for Leptin into the Brain
- (2014) Eglantine Balland et al. Cell Metabolism
- Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6
- (2013) R. Shirazi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- α-Tanycytes of the adult hypothalamic third ventricle include distinct populations of FGF-responsive neural progenitors
- (2013) S.C. Robins et al. Nature Communications
- Treating Diabetes and Obesity with an FGF21-Mimetic Antibody Activating the Klotho/FGFR1c Receptor Complex
- (2012) I. N. Foltz et al. Science Translational Medicine
- Involvement of the extracellular signal-regulated kinase 1/2 signaling pathway in amylin's eating inhibitory effect
- (2011) Catarina Soares Potes et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Agonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family
- (2011) Wilber Romero-Fernandez et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease
- (2011) N. Itoh et al. JOURNAL OF BIOCHEMISTRY
- Genetic Association and Gene Expression Analysis IdentifyFGFR1as a New Susceptibility Gene for Human Obesity
- (2011) Hong Jiao et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Obesity is associated with hypothalamic injury in rodents and humans
- (2011) Joshua P. Thaler et al. JOURNAL OF CLINICAL INVESTIGATION
- Ablation of AMP-activated protein kinase α1 and α2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo
- (2010) G. Sun et al. DIABETOLOGIA
- Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism
- (2010) Claire L. Dobson et al. mAbs
- Acute electrical stimulation of the subfornical organ induces feeding in satiated rats
- (2010) Pauline M. Smith et al. PHYSIOLOGY & BEHAVIOR
- Hypothalamic mechanisms in cachexia
- (2010) Aaron J. Grossberg et al. PHYSIOLOGY & BEHAVIOR
- MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity
- (2009) André Kleinridders et al. Cell Metabolism
- Hypothalamic inflammation and energy homeostasis: Resolving the paradox
- (2009) Joshua P. Thaler et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity
- (2009) M. Milanski et al. JOURNAL OF NEUROSCIENCE
- The FGF family: biology, pathophysiology and therapy
- (2009) Andrew Beenken et al. NATURE REVIEWS DRUG DISCOVERY
- Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
- (2008) Kelly A. Posey et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The subfornical organ: a central nervous system site for actions of circulating leptin
- (2008) P. M. Smith et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity
- (2008) Xiaoqing Zhang et al. CELL
- Mediobasal Hypothalamic p70 S6 Kinase 1 Modulates the Control of Energy Homeostasis
- (2008) Clémence Blouet et al. Cell Metabolism
- Hypothalamic ERK Mediates the Anorectic and Thermogenic Sympathetic Effects of Leptin
- (2008) K. Rahmouni et al. DIABETES
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