Importance of Tryptophan in Transforming an Amphipathic Peptide into a Pseudomonas aeruginosa-Targeted Antimicrobial Peptide

Design of Embedded-Hybrid Antimicrobial Peptides with Enhanced Cell Selectivity and Anti-Biofilm Activity

(2014) Wei Xu et al.   PLoS One

Design of imperfectly amphipathic α-helical antimicrobial peptides with enhanced cell selectivity

(2013) Xin Zhu et al.   Acta Biomaterialia

Electrostatics and flexibility drive membrane recognition and early penetration by the antimicrobial peptide dendrimer bH1

(2013) Harish K. Ravi et al.   CHEMICAL COMMUNICATIONS

The value of single-pathogen antibacterial agents

(2013) Brad Spellberg et al.   NATURE REVIEWS DRUG DISCOVERY

Platforms for antibiotic discovery

(2013) Kim Lewis   NATURE REVIEWS DRUG DISCOVERY

Effect of repetitive lysine–tryptophan motifs on the bactericidal activity of antimicrobial peptides

(2012) Ramamourthy Gopal et al.   AMINO ACIDS

Inhibition of Biofilm Formation by Esomeprazole in Pseudomonas aeruginosa and Staphylococcus aureus

(2012) Vandana Singh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inhibition of Bacterial Biofilm Formation and Swarming Motility by a Small Synthetic Cationic Peptide

(2012) César de la Fuente-Núñez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Strand Length-Dependent Antimicrobial Activity and Membrane-Active Mechanism of Arginine- and Valine-Rich β-Hairpin-Like Antimicrobial Peptides

(2012) Na Dong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Membrane interaction and secondary structure of de novo designed arginine-and tryptophan peptides with dual function

(2012) Hanna A. Rydberg et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antimicrobial HPA3NT3 peptide analogs: Placement of aromatic rings and positive charges are key determinants for cell selectivity and mechanism of action

(2012) Jong-Kook Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria

(2012) Inês M. Torcato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Rationally Designed α-Helical Broad-Spectrum Antimicrobial Peptides with Idealized Facial Amphiphilicity

(2012) Nikken Wiradharma et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Antibiotics, microbiota, and immune defense

(2012) Carles Ubeda et al.   TRENDS IN IMMUNOLOGY

The Pseudomonas aeruginosa membranes: A target for a new amphiphilic aminoglycoside derivative?

(2011) Myriam Ouberai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Multifunctional cationic host defence peptides and their clinical applications

(2011) Amy T. Y. Yeung et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Bacterial resistance mechanisms against host defense peptides

(2011) Tomaz Koprivnjak et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cyclic antimicrobial R-, W-rich peptides: the role of peptide structure and E. coli outer and inner membranes in activity and the mode of action

(2011) Christof Junkes et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Effects of peptide hydrophobicity on its incorporation in phospholipid membranes — an NMR and ellipsometry study

(2010) Greger Orädd et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane selectivity by W-tagging of antimicrobial peptides

(2010) Artur Schmidtchen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structural determinants of host defense peptides for antimicrobial activity and target cell selectivity

(2010) Daisuke Takahashi et al.   BIOCHIMIE

Synthetic cationic amphiphilic α-helical peptides as antimicrobial agents

(2010) Nikken Wiradharma et al.   BIOMATERIALS

Antimicrobial Peptides: Primeval Molecules or Future Drugs?

(2010) Brian M. Peters et al.   PLoS Pathogens

Tryptophan end-tagging of antimicrobial peptides for increased potency against Pseudomonas aeruginosa

(2009) Mukesh Pasupuleti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

End-Tagging of Ultra-Short Antimicrobial Peptides by W/F Stretches to Facilitate Bacterial Killing

(2009) Mukesh Pasupuleti et al.   PLoS One

Antibiotics for Emerging Pathogens

(2009) M. A. Fischbach et al.   SCIENCE

Binding of LL-37 to model biomembranes: Insight into target vs host cell recognition

(2008) Rohit Sood et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Effects of Cations and PH on Antimicrobial Activity of Thanatin and s-Thanatin Against Escherichia coli ATCC25922 and B. subtilis ATCC 21332

(2008) Guoqiu Wu et al.   CURRENT MICROBIOLOGY

Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation

(2008) J. Overhage et al.   INFECTION AND IMMUNITY

Evaluation of the inhibitory effects of human serum components on bactericidal activity of human beta defensin 3

(2007) Giuseppantonio Maisetta et al.   PEPTIDES