JAK2/STAT3 Inhibition Attenuates Noise-Induced Hearing Loss

Observation of unphosphorylated STAT3 core protein binding to targetdsDNA by PEMSA and X-ray crystallography

(2013) Edwin Nkansah et al.   FEBS LETTERS

Noise-induced changes in expression levels of NADPH oxidases in the cochlea

(2013) Srdjan M. Vlajkovic et al.   HEARING RESEARCH

New Role of JAK2/STAT3 Signaling in Endothelial Cell Oxidative Stress Injury and Protective Effect of Melatonin

(2013) Weixun Duan et al.   PLoS One

Activation of Stat3 in endothelial cells following hypoxia–reoxygenation is mediated by Rac1 and protein kinase C

(2012) Subhendra N. Mattagajasingh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Traumatic Noise Activates Rho-Family GTPases through Transient Cellular Energy Depletion

(2012) F.-Q. Chen et al.   JOURNAL OF NEUROSCIENCE

Ototoxicity: Mechanisms of Cochlear Impairment and its Prevention

(2011) K. Tabuchi et al.   CURRENT MEDICINAL CHEMISTRY

Mechanisms underlying somatostatin receptor 2 down-regulation of vascular endothelial growth factor expression in response to hypoxia in mouse retinal explants

(2011) Sara Mei et al.   JOURNAL OF PATHOLOGY

Dynamics of the STAT3 Transcription Factor: Nuclear Import Dependent on Ran and Importin-β1

(2011) Velasco Cimica et al.   PLoS One

Transtympanic Administration of Short Interfering (si)RNA for the NOX3 Isoform of NADPH Oxidase Protects Against Cisplatin-Induced Hearing Loss in the Rat

(2010) Debashree Mukherjea et al.   ANTIOXIDANTS & REDOX SIGNALING

Modulation of Gene Expression and Tumor Cell Growth by Redox Modification of STAT3

(2010) L. Li et al.   CANCER RESEARCH

Roles of NADPH Oxidases in Cisplatin-Induced Reactive Oxygen Species Generation and Ototoxicity

(2010) H.-J. Kim et al.   JOURNAL OF NEUROSCIENCE

Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells

(2010) Wei-Lun Huang et al.   Molecular Cancer

Signal Transducer and Activator of Transcription-3, Inflammation, and Cancer

(2009) Bharat B. Aggarwal et al.   Annals of the New York Academy of Sciences

JAK/STAT Signaling Pathway Regulates Nox1 and Nox4-Based NADPH Oxidase in Human Aortic Smooth Muscle Cells

(2009) Adrian Manea et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria

(2009) Lobelia Samavati et al.   MOLECULAR IMMUNOLOGY

Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress

(2009) J.C. Adams et al.   NEUROSCIENCE

Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea

(2009) Kenichiro Wakabayashi et al.   NEUROSCIENCE RESEARCH

NADPH Oxidase-Dependent Signaling in Endothelial Cells: Role in Physiology and Pathophysiology

(2008) Randall S. Frey et al.   ANTIOXIDANTS & REDOX SIGNALING