Formyl Peptide Receptor as a Novel Therapeutic Target for Anxiety-Related Disorders

A novel delivery platform for therapeutic peptides

(2014) Sunyoung Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Developmental rodent models of fear and anxiety: from neurobiology to pharmacology

(2014) Despina E Ganella et al.   BRITISH JOURNAL OF PHARMACOLOGY

Intraluminal Containment of Commensal Outgrowth in the Gut during Infection-Induced Dysbiosis

(2013) Michael J. Molloy et al.   Cell Host & Microbe

Formylpeptide receptor-2 contributes to colonic epithelial homeostasis, inflammation, and tumorigenesis

(2013) Keqiang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Redox signaling regulates commensal-mediated mucosal homeostasis and restitution and requires formyl peptide receptor 1

(2013) A Alam et al.   Mucosal Immunology

Chemosensory signals and their receptors in the olfactory neural system

(2013) S. Ihara et al.   NEUROSCIENCE

Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex

(2013) Iván J. Santos-Soto et al.   PLoS One

Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses

(2013) S. N. Cooray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WKYMVm-Induced Activation of Formyl Peptide Receptor 2 Stimulates Ischemic Neovasculogenesis by Promoting Homing of Endothelial Colony-Forming Cells

(2013) Soon Chul Heo et al.   STEM CELLS

Gut–brain axis: how the microbiome influences anxiety and depression

(2013) Jane A. Foster et al.   TRENDS IN NEUROSCIENCES

Predator stress-induced persistent emotional arousal is associated with alterations of plasma corticosterone and hippocampal steroid receptors in rat

(2012) Qingsong Wang et al.   BEHAVIOURAL BRAIN RESEARCH

Enhancement of Anxiety and Modulation of TH and pERK Expressions in Amygdala by Repeated Injections of Corticosterone

(2012) Hee-Na Lim et al.   Biomolecules & Therapeutics

Development of Hyperactivity and Anxiety Responses in Dopamine Transporter-Deficient Mice

(2012) Alex C. Carpenter et al.   DEVELOPMENTAL NEUROSCIENCE

Leukocyte recruitment in the brain in sepsis: involvement of the annexin 1-FPR2/ALX anti-inflammatory system

(2012) Felicity N. E. Gavins et al.   FASEB JOURNAL

Hip14l-deficient mice develop neuropathological and behavioural features of Huntington disease

(2012) Liza M. Sutton et al.   HUMAN MOLECULAR GENETICS

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Spreading paths in partially observed social networks

(2012) Jukka-Pekka Onnela et al.   PHYSICAL REVIEW E

Regulation of the Formyl Peptide Receptor 1 (FPR1) Gene in Primary Human Macrophages

(2012) Claudio Gemperle et al.   PLoS One

Overstimulation of newborn mice leads to behavioral differences and deficits in cognitive performance

(2012) D. A. Christakis et al.   Scientific Reports

Reduced Fear Memory and Anxiety-like Behavior in Mice Lacking Formylpeptide Receptor 1

(2011) Ji-Liang Gao et al.   BEHAVIOR GENETICS

Stress, stress hormones, and adult neurogenesis

(2011) Timothy J. Schoenfeld et al.   EXPERIMENTAL NEUROLOGY

Proinflammatory Stimulants Promote the Expression of a Promiscuous G Protein-Coupled Receptor, mFPR2, in Microvascular Endothelial Cells

(2011) Haiwei Mou et al.   INFLAMMATION

Enteric Commensal Bacteria Induce Extracellular Signal-regulated Kinase Pathway Signaling via Formyl Peptide Receptor-dependent Redox Modulation of Dual Specific Phosphatase 3

(2011) Christy C. Wentworth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Full characterization of GPCR monomer–dimer dynamic equilibrium by single molecule imaging

(2011) Rinshi S. Kasai et al.   JOURNAL OF CELL BIOLOGY

The microbiome-gut-brain axis: from bowel to behavior

(2011) J. F. Cryan et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Serotonergic neurotransmission in the ventral hippocampus is enhanced by corticosterone and altered by chronic amphetamine treatment

(2011) J.L. Barr et al.   NEUROSCIENCE

Normal gut microbiota modulates brain development and behavior

(2011) R. D. Heijtz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Commensal-Epithelial Signaling Mediated via Formyl Peptide Receptors

(2010) Christy C. Wentworth et al.   AMERICAN JOURNAL OF PATHOLOGY

Bacterial infection causes stress-induced memory dysfunction in mice

(2010) M. G. Gareau et al.   GUT

An animal model of eating disorders associated with stressful experience in early life

(2010) Jeong Won Jahng   HORMONES AND BEHAVIOR

From Vaccines to Memory and Back

(2010) Federica Sallusto et al.   IMMUNITY

Comparative analysis of Annexin A1-formyl peptide receptor 2/ALX expression in human leukocyte subsets

(2010) Lydia Spurr et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation

(2010) Neil Dufton et al.   JOURNAL OF IMMUNOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Expression and Signaling of Formyl-Peptide Receptors in the Brain

(2010) Fabio Cattaneo et al.   NEUROCHEMICAL RESEARCH

Reduced anxiety-like behavior and central neurochemical change in germ-free mice

(2010) K. M. Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Neuroimmune Interactions in Stress

(2010) Frederico A. Costa-Pinto et al.   NEUROIMMUNOMODULATION

Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists

(2010) Neil Dufton et al.   PHARMACOLOGY & THERAPEUTICS

Sex Differences in Behavioral and Corticosterone Responses to Mild Stressors in ICR Mice are Altered by Ovariectomy in Peripubertal Period

(2010) Mami Aoki et al.   ZOOLOGICAL SCIENCE

Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition

(2009) Giulio Taglialatela et al.   BEHAVIOURAL BRAIN RESEARCH

Postmortem molecular screening for mutations in ryanodine receptor type 1 (RYR1) gene in psychiatric patients suspected of having died of neuroleptic malignant syndrome

(2009) Takako Sato et al.   FORENSIC SCIENCE INTERNATIONAL

Activation of pre-synaptic M-type K+channels inhibits [3H]d-aspartate release by reducing Ca2+entry through P/Q-type voltage-gated Ca2+channels

(2009) Rosa Luisi et al.   JOURNAL OF NEUROCHEMISTRY

Noses within noses

(2009) Steven D. Munger   NATURE

Formyl peptide receptor-like proteins are a novel family of vomeronasal chemosensors

(2009) Stéphane Rivière et al.   NATURE

Neutralization of a unique, negatively-charged residue in the voltage sensor of KV7.2 subunits in a sporadic case of benign familial neonatal seizures

(2009) Francesco Miceli et al.   NEUROBIOLOGY OF DISEASE

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family

(2009) R. D. Ye et al.   PHARMACOLOGICAL REVIEWS

Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ

(2009) S. D. Liberles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opposing regulation of neutrophil apoptosis through the formyl peptide receptor-like 1/lipoxin A4 receptor: implications for resolution of inflammation

(2008) Driss El Kebir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Forced and voluntary exercise differentially affect brain and behavior

(2008) J.L. Leasure et al.   NEUROSCIENCE

Mice selected for high versus low stress reactivity: A new animal model for affective disorders

(2008) Chadi Touma et al.   PSYCHONEUROENDOCRINOLOGY