EGb761 Provides a Protective Effect against Aβ1-42 Oligomer-Induced Cell Damage and Blood-Brain Barrier Disruption in an In Vitro bEnd.3 Endothelial Model

Phospholipid transfer protein (PLTP) deficiency impaired blood–brain barrier integrity by increasing cerebrovascular oxidative stress

(2014) Ting Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Analog of Ginkgo biloba Extract 761 is a Protective Factor of Cognitive Impairment Induced by Chronic Fluorosis

(2013) Caiyi Zhang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

The potential mechanisms of Aβ-receptor for advanced glycation end-products interaction disrupting tight junctions of the blood-brain barrier in Alzheimer's disease

(2013) Wenbin Wan et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Moderate Hypoxia Followed by Reoxygenation Results in Blood-Brain Barrier Breakdown via Oxidative Stress-Dependent Tight-Junction Protein Disruption

(2013) Christoph M. Zehendner et al.   PLoS One

Tight Junction in Blood-Brain Barrier: An Overview of Structure, Regulation, and Regulator Substances

(2012) Wei-Ye Liu et al.   CNS Neuroscience & Therapeutics

Is RAGE still a therapeutic target for Alzheimer’s disease?

(2012) Richard J Deane   Future Medicinal Chemistry

Effects of the standardized Ginkgo biloba extract EGb 761® on neuroplasticity

(2012) Walter E. Müller et al.   INTERNATIONAL PSYCHOGERIATRICS

Ginkgo biloba leaf extract (EGb 761®) and its specific acylated flavonol constituents increase dopamine and acetylcholine levels in the rat medial prefrontal cortex: possible implications for the cognitive enhancing properties of EGb 761®

(2012) J. Kehr et al.   INTERNATIONAL PSYCHOGERIATRICS

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling

(2012) S.-Y. Kook et al.   JOURNAL OF NEUROSCIENCE

Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE) - and amyloid beta 1-42-induced signal transduction in glial cells

(2012) Alexander Slowik et al.   Molecular Neurodegeneration

Ischemia–reperfusion impairs blood–brain barrier function and alters tight junction protein expression in the ovine fetus

(2012) X. Chen et al.   NEUROSCIENCE

Effects of Ginkgolide A on Okadaic Acid-induced Tau Hyperphosphorylation and the PI3K-Akt Signaling Pathway in N2a Cells

(2012) Yan Chen et al.   PLANTA MEDICA

ZO Proteins and Redox-Dependent Processes

(2011) Lorenza González-Mariscal et al.   ANTIOXIDANTS & REDOX SIGNALING

Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

(2011) Anna Carrano et al.   ANTIOXIDANTS & REDOX SIGNALING

RAGE: The beneficial and deleterious effects by diverse mechanisms of actions

(2011) Sun-Ho Han et al.   MOLECULES AND CELLS

Amyloid Triggers Extensive Cerebral Angiogenesis Causing Blood Brain Barrier Permeability and Hypervascularity in Alzheimer's Disease

(2011) Kaan E. Biron et al.   PLoS One

WNT5A Signaling Contributes to Aβ-Induced Neuroinflammation and Neurotoxicity

(2011) Bei Li et al.   PLoS One

Advanced glycation endproducts: from precursors to RAGE: round and round we go

(2010) Ravichandran Ramasamy et al.   AMINO ACIDS

Ginkgolide B protects hippocampal neurons from apoptosis induced by beta-amyloid 25–35 partly via up-regulation of brain-derived neurotrophic factor

(2010) Qian Xiao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effects of Ginkgo biloba on cerebral blood flow assessed by quantitative MR perfusion imaging: a pilot study

(2010) Ameneh Mashayekh et al.   NEURORADIOLOGY

Effects of Ginkgo biloba in dementia: systematic review and meta-analysis

(2010) Stefan Weinmann et al.   BMC Geriatrics

Clearance of Amyloid-β Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimers Disease

(2009) R. Deane et al.   CNS & Neurological Disorders-Drug Targets

Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy

(2009) Seth Love   Frontiers in Bioscience-Landmark

Amyloid Deposition and Influx Transporter Expression at the Blood-Brain Barrier Increase in Normal Aging

(2009) Gerald D. Silverberg et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Effects of ginkgo biloba extract EGb761 on expression of RAGE and LRP-1 in cerebral microvascular endothelial cells under chronic hypoxia and hypoglycemia

(2008) Fu-Ling Yan et al.   ACTA NEUROPATHOLOGICA

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE