Circulating Programmed Death-1 as a Marker for Sustained High Hepatitis B Viral Load and Risk of Hepatocellular Carcinoma

Impact of Genetic Heterogeneity in Polymerase of Hepatitis B Virus on Dynamics of Viral Load and Hepatitis B Progression

(2013) Chi-Jung Huang et al.   PLoS One

New insight in the pathobiology of hepatitis B virus infection

(2012) Maura Dandri et al.   GUT

Influences of tobacco and alcohol use on hepatocellular carcinoma survival

(2012) Wei-Liang Shih et al.   INTERNATIONAL JOURNAL OF CANCER

Ethnic differences in viral dominance patterns in patients with hepatitis B virus and hepatitis C virus dual infection

(2011) Long H. Nguyen et al.   HEPATOLOGY

PD-1 and PD-L1 upregulation promotes CD8+ T-cell apoptosis and postoperative recurrence in hepatocellular carcinoma patients

(2010) Feng Shi et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

(2010) Kaori Sakuishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Etiology of Hepatocellular Carcinoma and Consequences for Treatment

(2010) A. J. Sanyal et al.   ONCOLOGIST

Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

(2009) M. Ahmadzadeh et al.   BLOOD

Hepatitis B Virus Core Variants Modify Natural Course of Viral Infection and Hepatocellular Carcinoma Progression

(2009) Feng–Yu Sung et al.   GASTROENTEROLOGY

Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B

(2009) Paola Fisicaro et al.   GASTROENTEROLOGY

Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

(2008) Nobuhiro Nakamoto et al.   GASTROENTEROLOGY

Programmed death 1 expression during antiviral treatment of chronic hepatitis B: Impact of hepatitis B e-antigen seroconversion

(2008) Alexander Evans et al.   HEPATOLOGY

Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update

(2008) Yun-Fan Liaw et al.   Hepatology International

Body-Mass Index and Progression of Hepatitis B: A Population-Based Cohort Study in Men

(2008) Ming-Whei Yu et al.   JOURNAL OF CLINICAL ONCOLOGY

High Viral Load and Hepatitis B Virus Subgenotype Ce Are Associated With Increased Risk of Hepatocellular Carcinoma

(2008) Henry Lik-Yuen Chan et al.   JOURNAL OF CLINICAL ONCOLOGY

Enhancing SIV-specific immunity in vivo by PD-1 blockade

(2008) Vijayakumar Velu et al.   NATURE

Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1–Specific CD8+ T Cells

(2008) Hendrik Streeck et al.   PLOS MEDICINE