CD137 Expression Is Induced by Epstein-Barr Virus Infection through LMP1 in T or NK Cells and Mediates Survival Promoting Signals

CD137 Is Induced by the CD40 Signal on Chronic Lymphocytic Leukemia B Cells and Transduces the Survival Signal via NF-κB Activation

(2013) Yukana Nakaima et al.   PLoS One

CD137 Is Expressed in Follicular Dendritic Cell Tumors and in Classical Hodgkin and T-Cell Lymphomas

(2012) Matthew W. Anderson et al.   AMERICAN JOURNAL OF PATHOLOGY

EBV-associated T/NK-cell lymphoproliferative diseases in nonimmunocompromised hosts: prospective analysis of 108 cases

(2011) H. Kimura et al.   BLOOD

Clinical features of adult-onset chronic active Epstein–Barr virus infection: a retrospective analysis

(2011) Ayako Arai et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Phase II Study of SMILE Chemotherapy for Newly Diagnosed Stage IV, Relapsed, or Refractory Extranodal Natural Killer (NK)/T-Cell Lymphoma, Nasal Type: The NK-Cell Tumor Study Group Study

(2011) Motoko Yamaguchi et al.   JOURNAL OF CLINICAL ONCOLOGY

CD40 Is Essential in the Upregulation of TRAF Proteins and NF-KappaB-Dependent Proinflammatory Gene Expression after Arterial Injury

(2011) Zifang Song et al.   PLoS One

Novel Mouse Xenograft Models Reveal a Critical Role of CD4+ T Cells in the Proliferation of EBV-Infected T and NK Cells

(2011) Ken-Ichi Imadome et al.   PLoS Pathogens

CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells

(2010) H. Narazaki et al.   BLOOD

Excellent outcome of allogeneic hematopoietic SCT with reduced-intensity conditioning for the treatment of chronic active EBV infection

(2010) K Kawa et al.   BONE MARROW TRANSPLANTATION

Epstein‐Barr Virus–Associated Hemophagocytic Lymphohistiocytosis in Adults Characterized by High Viral Genome Load within Circulating Natural Killer Cells

(2010) C. P. Fox et al.   CLINICAL INFECTIOUS DISEASES

CD137 ligand, a member of the tumor necrosis factor family, regulates immune responses via reverse signal transduction

(2010) Zhe Shao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Reporting Animal Studies: Good Science and a Duty of Care

(2010) Catriona J. MacCallum   PLOS BIOLOGY

Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma

(2009) S. Middendorp et al.   BLOOD

Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia

(2009) Y. Yamanaka et al.   BLOOD

Strong induction of 4-1BB, a growth and survival promoting costimulatory receptor, in HTLV-1-infected cultured and patients' T cells by the viral Tax oncoprotein

(2008) K. Pichler et al.   BLOOD

Epstein-Barr Virus-Encoded LMP1 Regulates Epithelial Cell Motility and Invasion via the ERK-MAPK Pathway

(2008) C. W. Dawson et al.   JOURNAL OF VIROLOGY

Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells

(2008) Seung-Woo Lee et al.   NATURE IMMUNOLOGY

The c-Jun N-terminal kinase pathway is critical for cell transformation by the latent membrane protein 1 of Epstein–Barr virus

(2007) Helmut Kutz et al.   VIROLOGY