Mimulone-Induced Autophagy through p53-Mediated AMPK/mTOR Pathway Increases Caspase-Mediated Apoptotic Cell Death in A549 Human Lung Cancer Cells

Inhibition of protein kinase C α/βII and activation of c-Jun NH2-terminal kinase mediate glycyrrhetinic acid induced apoptosis in non-small cell lung cancer NCI-H460 cells

(2014) Junho Song et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Glycyrrhizin Suppresses Lung Adenocarcinoma Cell Growth Through Inhibition of Thromboxane Synthase

(2014) Run-Yue Huang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Induction of Lung Cancer Cell Apoptosis through a p53 Pathway by [6]-Shogaol and Its Cysteine-Conjugated Metabolite M2

(2014) Renaud F. Warin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Activation of p38/JNK Pathway Is Responsible for Embelin Induced Apoptosis in Lung Cancer Cells: Transitional Role of Reactive Oxygen Species

(2014) Deepa R. Avisetti et al.   PLoS One

Why should autophagic flux be assessed?

(2013) Xiao-jie Zhang et al.   ACTA PHARMACOLOGICA SINICA

Management of non-small-cell lung cancer: recent developments

(2013) Martin Reck et al.   LANCET

Minor C-geranylated flavanones from Paulownia tomentosa fruits with MRSA antibacterial activity

(2013) Alice Navrátilová et al.   PHYTOCHEMISTRY

Dendropanoxide Induces Autophagy through ERK1/2 Activation in MG-63 Human Osteosarcoma Cells and Autophagy Inhibition Enhances Dendropanoxide-Induced Apoptosis

(2013) Ji-Won Lee et al.   PLoS One

Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents

(2012) X. Zhang et al.   CELL PROLIFERATION

Tomentomimulol and mimulone B: Two newC-geranylated flavonoids fromPaulownia tomentosafruits

(2012) K. Schneiderová et al.   NATURAL PRODUCT RESEARCH

Aristolochic Acid I Induced Autophagy Extenuates Cell Apoptosis via ERK 1/2 Pathway in Renal Tubular Epithelial Cells

(2012) Youjia Zeng et al.   PLoS One

Autophagy and Cancer

(2012) Francesca Aredia et al.   Cells

Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53

(2011) Kaipeng Jing et al.   Autophagy

Autophagy as a mediator of chemotherapy-induced cell death in cancer

(2011) Annick Notte et al.   BIOCHEMICAL PHARMACOLOGY

Lung cancer: New biological insights and recent therapeutic advances

(2011) Suresh S. Ramalingam et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells

(2011) Guangmin Xi et al.   CANCER LETTERS

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Autophagy Inhibition Enhances Daunorubicin-Induced Apoptosis in K562 Cells

(2011) Weidong Han et al.   PLoS One

Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria- and Fas/FasL-mediated pathways

(2011) Haibo Mou et al.   TOXICOLOGY IN VITRO

Autophagy and apoptosis: what is the connection?

(2011) Jacob M. Gump et al.   TRENDS IN CELL BIOLOGY

Anti-cancer natural products isolated from chinese medicinal herbs

(2011) Wen Tan et al.   Chinese Medicine

Geranylated flavanone tomentodiplacone B inhibits proliferation of human monocytic leukaemia (THP-1) cells

(2010) Peter Kollár et al.   BRITISH JOURNAL OF PHARMACOLOGY

Autophagy regulation by p53

(2010) Maria Chiara Maiuri et al.   CURRENT OPINION IN CELL BIOLOGY

Cytotoxic Activities of Several Geranyl-Substituted Flavanones

(2010) Karel Šmejkal et al.   JOURNAL OF NATURAL PRODUCTS

Cancer Chemoprevention by Natural Products: How Far Have We Come?

(2010) Rajendra G. Mehta et al.   PHARMACEUTICAL RESEARCH

Neuroprotective effects of a sesquiterpene lactone and flavanones from Paulownia tomentosa Steud. against glutamate-induced neurotoxicity in primary cultured rat cortical cells

(2010) Soo-Ki Kim et al.   PHYTOTHERAPY RESEARCH

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

6-Shogaol, an Active Constituent of Dietary Ginger, Induces Autophagy by Inhibiting the AKT/mTOR Pathway in Human Non-Small Cell Lung Cancer A549 Cells

(2009) Jen-Yu Hung et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Glossogin, a novel phenylpropanoid from Glossogyne tenuifolia, induced apoptosis in A549 lung cancer cells

(2008) Hsia-Fen Hsu et al.   FOOD AND CHEMICAL TOXICOLOGY

p53: The Janus of autophagy?

(2008) Beth Levine et al.   NATURE CELL BIOLOGY

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY

Geranylated flavanones from the secretion on the surface of the immature fruits of Paulownia tomentosa

(2008) Teigo Asai et al.   PHYTOCHEMISTRY

Cytotoxic Activity ofC-Geranyl Compounds fromPaulownia tomentosaFruits

(2008) Karel Šmejkal et al.   PLANTA MEDICA