Identification of Natural Compound Inhibitors for Multidrug Efflux Pumps of Escherichia coli and Pseudomonas aeruginosa Using In Silico High-Throughput Virtual Screening and In Vitro Validation

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

(2013) G. Madhavi Sastry et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Structural basis for the inhibition of bacterial multidrug exporters

(2013) Ryosuke Nakashima et al.   NATURE

Pharmacophore modeling and virtual screening studies to design potential COMT inhibitors as new leads

(2012) Nidhi Jatana et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Molecular modeling study of checkpoint kinase 1 inhibitors by multiple docking strategies and prime/MM-GBSA calculation

(2011) Juan Du et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Pseudomonas aeruginosa: all roads lead to resistance

(2011) Elena B.M. Breidenstein et al.   TRENDS IN MICROBIOLOGY

A 96-well plate fluorescence assay for assessment of cellular permeability and active efflux in Salmonella enterica serovar Typhimurium and Escherichia coli

(2010) N. G. Coldham et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Influence of efflux pump inhibitors on the multidrug resistance ofHelicobacter pylori

(2010) Zhan Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Efflux pump inhibitors reduce the invasiveness of Pseudomonas aeruginosa

(2009) Yoichi Hirakata et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa

(2009) Gaby Sennhauser et al.   JOURNAL OF MOLECULAR BIOLOGY

Combining docking with pharmacophore filtering for improved virtual screening

(2009) Megan L Peach et al.   Journal of Cheminformatics

Novel structural analogues of piperine as inhibitors of the NorA efflux pump of Staphylococcus aureus

(2008) A. Kumar et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Plant phenolic compounds as ethidium bromide efflux inhibitors in Mycobacterium smegmatis

(2008) D. Lechner et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Site-Directed Mutagenesis Reveals Putative Substrate Binding Residues in the Escherichia coli RND Efflux Pump AcrB

(2008) J. A. Bohnert et al.   JOURNAL OF BACTERIOLOGY

Synergism between natural products and antibiotics against infectious diseases

(2008) Shanmugam Hemaiswarya et al.   PHYTOMEDICINE