Differentiated Type II Pneumocytes Can Be Reprogrammed by Ectopic Sox2 Expression

Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated MicroRNA Circuits

(2013) Yuanchao Xue et al.   CELL

Reprogramming in vivo produces teratomas and iPS cells with totipotency features

(2013) María Abad et al.   NATURE

Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

(2013) Fadi J Najm et al.   NATURE BIOTECHNOLOGY

In vivo reprogramming of astrocytes to neuroblasts in the adult brain

(2013) Wenze Niu et al.   NATURE CELL BIOLOGY

Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies

(2013) Julia Ladewig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hypoxia Inducible Factor 3α Plays a Critical Role in Alveolarization and Distal Epithelial Cell Differentiation during Mouse Lung Development

(2013) Yadi Huang et al.   PLoS One

A Cellular Pathway Involved in Clara Cell to Alveolar Type II Cell Differentiation after Severe Lung Injury

(2013) Dahai Zheng et al.   PLoS One

Generation of induced neurons via direct conversion in vivo

(2013) O. Torper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From Stealing Fire to Cellular Reprogramming: A Scientific History Leading to the 2012 Nobel Prize

(2013) M. William Lensch et al.   Stem Cell Reports

Two-factor reprogramming of somatic cells to pluripotent stem cells reveals partial functional redundancy of Sox2 and Klf4

(2012) A Nemajerova et al.   CELL DEATH AND DIFFERENTIATION

Efficient Derivation of Purified Lung and Thyroid Progenitors from Embryonic Stem Cells

(2012) Tyler A. Longmire et al.   Cell Stem Cell

Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs and Patient-Specific Cystic Fibrosis iPSCs

(2012) Hongmei Mou et al.   Cell Stem Cell

Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors

(2012) Dong Wook Han et al.   Cell Stem Cell

Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

(2012) Karen L. Ring et al.   Cell Stem Cell

Cell fate conversion: Direct induction of hepatocyte-like cells from fibroblasts

(2012) Shuyi Ji et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Building and maintaining the epithelium of the lung

(2012) Craig R. Rackley et al.   JOURNAL OF CLINICAL INVESTIGATION

Lineage conversion methodologies meet the reprogramming toolbox

(2012) Ignacio Sancho-Martinez et al.   NATURE CELL BIOLOGY

Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells

(2012) E. Lujan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: Deconstructing the Lung to Reveal Its Regenerative Potential

(2012) Jonathan L. McQualter et al.   STEM CELLS

Airway Epithelial Progenitors Are Region Specific and Show Differential Responses to Bleomycin-Induced Lung Injury

(2012) Huaiyong Chen et al.   STEM CELLS

SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype

(2012) Lalini Raghoebir et al.   Journal of Molecular Cell Biology

Stem cells of the adult lung: their development and role in homeostasis, regeneration, and disease

(2012) Carolien Wansleeben et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Hypoxia-Inducible Factor 2α Plays a Critical Role in the Formation of Alveoli and Surfactant

(2011) Yadi Huang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Epithelial Progenitor Cells in Lung Development, Maintenance, Repair, and Disease

(2011) Jason R. Rock et al.   Annual Review of Cell and Developmental Biology

Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors

(2011) Chao Sheng et al.   CELL RESEARCH

Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions

(2011) Rajesh Ambasudhan et al.   Cell Stem Cell

Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons

(2011) Samuele Marro et al.   Cell Stem Cell

Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice

(2011) Harold A. Chapman et al.   JOURNAL OF CLINICAL INVESTIGATION

Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

(2011) Massimiliano Caiazzo et al.   NATURE

Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells

(2011) Michael D Green et al.   NATURE BIOTECHNOLOGY

Direct reprogramming of mouse fibroblasts to neural progenitors

(2011) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming of Trophoblast Stem Cells into Pluripotent Stem Cells by Oct4

(2011) Tong Wu et al.   STEM CELLS

Sox2 Activates Cell Proliferation and Differentiation in the Respiratory Epithelium

(2010) David H. Tompkins et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Context-Dependent Differentiation of Multipotential Keratin 14–Expressing Tracheal Basal Cells

(2010) Moumita Ghosh et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling

(2010) J. R. Rock et al.   Disease Models & Mechanisms

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Evidence That SOX2 Overexpression Is Oncogenic in the Lung

(2010) Yun Lu et al.   PLoS One

Sox2 Uses Multiple Domains to Associate with Proteins Present in Sox2-Protein Complexes

(2010) Jesse L. Cox et al.   PLoS One

Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung

(2010) J. L. McQualter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins

(2009) Dohoon Kim et al.   Cell Stem Cell

The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

(2009) Emma L. Rawlins et al.   Cell Stem Cell

Multiple roles for Sox2 in the developing and adult mouse trachea

(2009) J. Que et al.   DEVELOPMENT

Forcing cells to change lineages

(2009) Thomas Graf et al.   NATURE

Sox17 Promotes Cell Cycle Progression and Inhibits TGF-β/Smad3 Signaling to Initiate Progenitor Cell Behavior in the Respiratory Epithelium

(2009) Alexander W. Lange et al.   PLoS One

Sox2 Is Required for Maintenance and Differentiation of Bronchiolar Clara, Ciliated, and Goblet Cells

(2009) David H. Tompkins et al.   PLoS One

Stem cells are dispensable for lung homeostasis but restore airways after injury

(2009) A. Giangreco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sox2 is important for two crucial processes in lung development: Branching morphogenesis and epithelial cell differentiation

(2008) Cristina Gontan et al.   DEVELOPMENTAL BIOLOGY

The Molecular Mechanism Governing the Oncogenic Potential of SOX2 in Breast Cancer

(2008) Yupeng Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE