Tumor Microenvironmental Changes Induced by the Sulfamate Carbonic Anhydrase IX Inhibitor S4 in a Laryngeal Tumor Model
出版年份 2014 全文链接
标题
Tumor Microenvironmental Changes Induced by the Sulfamate Carbonic Anhydrase IX Inhibitor S4 in a Laryngeal Tumor Model
作者
关键词
-
出版物
PLoS One
Volume 9, Issue 9, Pages e108068
出版商
Public Library of Science (PLoS)
发表日期
2014-09-17
DOI
10.1371/journal.pone.0108068
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors
- (2013) Giuseppina De Simone et al. Expert Opinion on Drug Discovery
- Elucidation of How Cancer Cells Avoid Acidosis through Comparative Transcriptomic Data Analysis
- (2013) Kun Xu et al. PLoS One
- Predictive value of hypoxia, proliferation and tyrosine kinase receptors for EGFR-inhibition and radiotherapy sensitivity in head and neck cancer models
- (2013) Hanneke Stegeman et al. RADIOTHERAPY AND ONCOLOGY
- Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines
- (2012) Jean-Yves Winum et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck
- (2012) Hanneke Stegeman et al. BMC CANCER
- Targeting Hypoxia, HIF-1, and Tumor Glucose Metabolism to Improve Radiotherapy Efficacy
- (2012) T. W. H. Meijer et al. CLINICAL CANCER RESEARCH
- Inhibition of carbonic anhydrase activity modifies the toxicity of doxorubicin and melphalan in tumour cellsin vitro
- (2012) Roben G. Gieling et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Antimetastatic Effect of Sulfamate Carbonic Anhydrase IX Inhibitors in Breast Carcinoma Xenografts
- (2012) Roben G. Gieling et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
- (2011) Y. Lou et al. CANCER RESEARCH
- Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors
- (2011) Nadia Touisni et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis
- (2011) Fabio Pacchiano et al. JOURNAL OF MEDICINAL CHEMISTRY
- Interfering with pH regulation in tumours as a therapeutic strategy
- (2011) Dario Neri et al. NATURE REVIEWS DRUG DISCOVERY
- Tumor-associated carbonic anhydrase XII is linked to the growth of primary oral squamous cell carcinoma and its poor prognosis
- (2011) Ming-Hsien Chien et al. ORAL ONCOLOGY
- Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation
- (2011) Ludwig Dubois et al. RADIOTHERAPY AND ONCOLOGY
- Overexpression of carbonic anhydrase XII in tissues from resectable non-small cell lung cancers is a biomarker of good prognosis
- (2010) Marius I. Ilie et al. INTERNATIONAL JOURNAL OF CANCER
- Selective Inhibition of Carbonic Anhydrase IX Decreases Cell Proliferation and Induces Ceramide-Mediated Apoptosis in Human Cancer Cells
- (2010) F. Cianchi et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A clinical phase I/II trial with the monoclonal antibody cG250 (RENCAREX®) and interferon-alpha-2a in metastatic renal cell carcinoma patients
- (2010) M. Siebels et al. WORLD JOURNAL OF UROLOGY
- In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives
- (2009) Julia K.J. Ahlskog et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
- (2009) Kasper M.A. Rouschop et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH
- (2008) J. Chiche et al. CANCER RESEARCH
- Cancer-Associated Carbonic Anhydrases and Their Inhibition
- (2008) J. Pastorek et al. CURRENT PHARMACEUTICAL DESIGN
- Causes and Consequences of Increased Glucose Metabolism of Cancers
- (2008) R. J. Gillies et al. JOURNAL OF NUCLEAR MEDICINE
- Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
- (2008) Claudiu T. Supuran NATURE REVIEWS DRUG DISCOVERY
- Intracellular pH regulation in oral squamous cell carcinoma is mediated by increased V-ATPase activity via over-expression of the ATP6V1C1 gene
- (2007) Eva María Otero-Rey et al. ORAL ONCOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now