期刊
ARTHRITIS CARE & RESEARCH
卷 67, 期 11, 页码 1513-1520出版社
WILEY
DOI: 10.1002/acr.22627
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类别
资金
- National Eye Institute [K23EY021760]
- Arthritis Foundation New York Chapter
- Weill Cornell Medical College Clinical and Translational Science Center [UL1-RR-0024996]
- Emory Egleston Children's Research Center
- Knights Templar Eye Foundation
- Career Development Bridge Funding Award from the American College of Rheumatology Research and Education Foundation
- Arthritis Foundation
- National Institute of Arthritis and Musculoskeletal and Skin Diseases/NIH [R01-AR-060893]
- Marcus Foundation
ObjectiveThe Effects of Youngsters' Eyesight on Quality of Life (EYE-Q) is a novel measure of vision-related quality of life (QOL) and function in children. We aim to determine the validity of the EYE-Q in childhood uveitis. MethodsWe abstracted medical record data on arthritis and uveitis in a convenience sample of children with juvenile idiopathic arthritis (JIA) and/or uveitis. In addition to the EYE-Q, parents and patients completed questionnaires on overall QOL (Pediatric Quality of Life Inventory [PedsQL]), and physical functioning (Childhood Health Assessment Questionnaire [C-HAQ]). ResultsAmong 57 children (8 JIA, 24 JIA and uveitis, 25 uveitis alone), 102 ocular examinations were performed within 1 month of completing questionnaires. Uveitis patients had bilateral disease (69%), anterior involvement (78%), synechiae (51%), and cataracts (49%). Children with vision loss in their better eye (visual acuity [VA] 20/50 or worse) had worse EYE-Q (P=0.006) and PedsQL (P=0.028) scores, but not C-HAQ scores. The EYE-Q moderately correlated with logMAR VA (r(s)=-0.43), PedsQL (r(s)=0.43), and C-HAQ (r(s)=-0.45), but was not correlated with anterior chamber cells or intraocular pressure. The PedsQL and C-HAQ did not correlate with VA or cells. There were strong correlations between the parent and child EYE-Q (r(s)=0.62). Cronbach's for the child report was 0.91. The EYE-Q had strong test-retest reliability (r(s)=0.75). ConclusionThe EYE-Q may be an important tool in the assessment of visual outcomes in childhood uveitis and an improvement over general measures in detecting changes in vision-related function.
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