Knock-Down of IL-1Ra in Obese Mice Decreases Liver Inflammation and Improves Insulin Sensitivity

In Vitro and In Vivo Activity of a Novel Locked Nucleic Acid (LNA)-Inhibitor-miR-221 against Multiple Myeloma Cells

(2014) Maria Teresa Di Martino et al.   PLoS One

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet-Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis

(2011) F. C. McGillicuddy et al.   DIABETES

Insulin-like Growth Factor 1-mediated Hyperthermia Involves Anterior Hypothalamic Insulin Receptors

(2011) Manuel Sanchez-Alavez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treatment with Anakinra Improves Disposition Index But Not Insulin Sensitivity in Nondiabetic Subjects with the Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study

(2011) Edwin J. P. van Asseldonk et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense

(2011) Sterghios A Moschos et al.   MOLECULAR THERAPY

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

(2010) Da Young Oh et al.   CELL

Accelerated Increase in Serum Interleukin-1 Receptor Antagonist Starts 6 Years Before Diagnosis of Type 2 Diabetes: Whitehall II Prospective Cohort Study

(2010) M. Carstensen et al.   DIABETES

XOMA 052, an Anti-IL-1β Monoclonal Antibody, Improves Glucose Control and β-Cell Function in the Diet-Induced Obesity Mouse Model

(2010) Alexander M. Owyang et al.   ENDOCRINOLOGY

Thirty-One Novel Biomarkers as Predictors for Clinically Incident Diabetes

(2010) Veikko Salomaa et al.   PLoS One

A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo

(2010) Nidhi Gupta et al.   PLoS One

Treatment with the PPARγ agonist rosiglitazone downregulates interleukin-1 receptor antagonist in individuals with metabolic syndrome

(2009) Bente Halvorsen et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity

(2008) O. Osborn et al.   CYTOKINE

Elevated Levels of the Anti-Inflammatory Interleukin-1 Receptor Antagonist Precede the Onset of Type 2 Diabetes: The Whitehall II Study

(2008) C. Herder et al.   DIABETES CARE

Levels of adiponectin, C‐reactive protein and interleukin‐1 receptor antagonist are associated with insulin sensitivity: a population‐based study

(2008) J. Saltevo et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Increased fat:carbohydrate oxidation ratio in Il1ra −/− mice on a high-fat diet is associated with increased sympathetic tone

(2008) D. Chida et al.   DIABETOLOGIA

The Antiinflammatory Cytokine Interleukin-1 Receptor Antagonist Protects from High-Fat Diet-Induced Hyperglycemia

(2008) Nadine S. Sauter et al.   ENDOCRINOLOGY

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

(2008) T. Yoshizaki et al.   MOLECULAR AND CELLULAR BIOLOGY