Phase 1 Study of the E-Selectin Inhibitor GMI 1070 in Patients with Sickle Cell Anemia

Exchange Transfusion Therapy and Its Effects on Real-time Microcirculation in Pediatric Sickle Cell Anemia Patients

(2013) Anthony T.W. Cheung et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Comparison of real-time microvascular abnormalities in pediatric and adult sickle cell anemia patients

(2010) Anthony T.W. Cheung et al.   AMERICAN JOURNAL OF HEMATOLOGY

GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice

(2010) J. Chang et al.   BLOOD

Sickle-cell disease

(2010) David C Rees et al.   LANCET

Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury

(2009) Andrés Hidalgo et al.   NATURE MEDICINE

Adhesion molecules and hydroxyurea in the pathophysiology of sickle cell disease

(2008) C. Johnson et al.   HAEMATOLOGICA

Increased adhesive properties of neutrophils in sickle cell disease may be reversed by pharmacological nitric oxide donation

(2008) A. A. Canalli et al.   HAEMATOLOGICA

Sickle Red Cell–Endothelium Interactions

(2008) Dhananjay K. Kaul et al.   MICROCIRCULATION

Role and regulation of sickle red cell interactions with other cells: ICAM-4 and other adhesion receptors

(2008) R. Zennadi et al.   TRANSFUSION CLINIQUE ET BIOLOGIQUE

Hydroxyurea attenuates activated neutrophil-mediated sickle erythrocyte membrane phosphatidylserine exposure and adhesion to pulmonary vascular endothelium

(2007) Johnson Haynes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY