Article
Multidisciplinary Sciences
Ke Mo, Yu Zhang, Zheng Dong, Yuhang Yang, Xiaoqiang Ma, Ben L. Feringa, Depeng Zhao
Summary: Scientists have designed synthetic molecular motors that can be driven by chemical energy and have intrinsic control over the direction of rotation, simple autonomous motion, and near-perfect unidirectionality. This study demonstrates the potential for future generations of multicomponent machines to perform mechanical functions.
Article
Engineering, Biomedical
Ruslan Garifullin, Mustafa O. Guler
Summary: This review discusses the use of self-assembling peptide molecules and electroactive units in supramolecular functional electronic and optical materials, with potential biomedical and bioelectronics applications.
MATERIALS TODAY BIO
(2021)
Review
Biochemistry & Molecular Biology
Traian Constantin, Mihai Pavalean, Stefana Bucur, Maria Magdalena Constantin, Alin Codrut Nicolescu, Irina Pacu, Victor Madan
Summary: Bladder cancer animal models can be categorized as either autochthonous or non-autochthonous, with the non-autochthonous models further classified into syngeneic and xenograft models. These models have different characteristics and applications based on the type of tumor implantation.
Article
Engineering, Multidisciplinary
Mariusz Ksiazek
Summary: The author explores the potential use of polymerized sulfur waste as a biocompatible material in biomaterial production, particularly in surgical applications. Experimental studies have demonstrated that polymerized sulfur waste shows promise as a biocomposite, opening up new possibilities for the industry.
COMPOSITES PART B-ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Alana N. Vagnozzi, Jian-Guo Li, Jin Chiu, Roshanak Razmpour, Rebecca Warfield, Servio H. Ramirez, Domenico Pratico
Summary: VPS35 plays a crucial role in tau metabolism and neuropathology, with its overexpression reducing pathological tau in neuronal cells while genetic silencing leads to accumulation. The availability of active cathepsin D mediates the effect of VPS35 on pathological tau accumulation, making it a potential therapeutic target for human tauopathies.
MOLECULAR PSYCHIATRY
(2021)
Article
Behavioral Sciences
Etedal Ahmed A. Ibrahim, Ghada A. Mutaal Badri, Khabab Abbasher Hussien Mohamed Ahmed, Mohammed Eltahier Abdalla Omer
Summary: The study found that environmental conditions were the most common triggers of migraine headache among Sudanese patients, while Acetaminophen was the most commonly used drug for relieving migraine in this population. The majority of patients were female (80%), aged 26-35 years (56.9%), and a significant proportion were housewives (40%).
BRAIN AND BEHAVIOR
(2021)
Review
Humanities, Multidisciplinary
Ahmad Fekry Moussa, Ibrahim Suleiman Al Qatawneh, Moustafa Elmetwaly Kandeel
Summary: This study focuses on the procedural necessity of primary investigations in the Arab countries, particularly in Egypt. It analyzes the position of the Arab procedural legislation and judiciary systems regarding procedural necessity and argues against expanding discretionary powers that may lead to abuse of officials and restrict individual rights and freedoms.
HUMANITIES & SOCIAL SCIENCES COMMUNICATIONS
(2022)
Article
Environmental Sciences
Yin Lu, Qin Ma, Xiaolu Xu, Zhefu Yu, Tianjiao Guo, Yangkai Wu
Summary: The study showed that exposure to poly styrene microplastics (PS-MPs) can lead to increased apoptosis and cell death, higher micronucleus rate, and reduced mitotic index in V. faba root cells. Additionally, it causes significant oxidative stress by altering the expression of antioxidant enzymes and genes related to cell cycle and DNA repair.
ENVIRONMENTAL POLLUTION
(2021)
Article
Physics, Multidisciplinary
Gabriel Koch Ocker
Summary: This study presents a statistical field theory for networks of integrate-and-fire neurons with stochastic spike emission, revealing the impact of spike-driven reset of the membrane voltage on population activity. The study uncovers bistability and fluctuation effects in the mean-field dynamics, as well as the roles of spike resets and recurrent inhibition in stabilizing network activity. It also calculates the phase diagram for inhibitory stabilization and finds that wide regions of parameter space exhibit inhibition-stabilized regime.
Article
Engineering, Chemical
James Dufty, Jeffrey Wrighton, Kai Luo
Summary: This article considers definitions for local pressure in an inhomogeneous fluid, covering both equilibrium and local equilibrium states, and reconciles thermodynamic and mechanical (hydrodynamic) contexts. Remaining problems and uncertainties in the topic are also discussed.
Article
Multidisciplinary Sciences
Peter C. Chu
Summary: In ocean dynamics, two different treatments are found for horizontal pressure gradient force and gravity, with vertical component being much larger than horizontal in both cases. Horizontal pressure gradient force is considered dominant, while horizontal gravity is completely omitted in oceanography. The importance of horizontal gravity is identified using a non-dimensional C number, with global data showing an unexpectedly large C number around 24.
SCIENTIFIC REPORTS
(2021)
Article
Education & Educational Research
Olga Garanina, Nidal Al Said, Valery Stepenko, Marija Troyanskaya
Summary: The study developed and tested an original model illustrating personality development in the information society, finding that its implementation increased students' use of resources for personal growth. The model's practical value lies in its applicability to higher education systems in various countries, especially in the context of distance learning and social isolation caused by the COVID-19 pandemic.
EDUCATION AND INFORMATION TECHNOLOGIES
(2021)
Article
Agricultural Engineering
Jiangkuan Xing, Ryoichi Kurose, Kun Luo, Jianren Fan
Summary: Researchers have developed a new tool for establishing solid fuel conversion kinetics from thermogravimetric analysis (TGA) measurements using chemistry-informed machine learning approaches. The derived pyrolysis kinetics accurately reproduce the pyrolysis process for different biomass types and demonstrate advantages in predicting volatiles yield.
BIORESOURCE TECHNOLOGY
(2022)
Article
Clinical Neurology
Julian Klingbeil, Max-Lennart Brandt, Max Wawrzyniak, Anika Stockert, Hans R. Schneider, Petra Baum, Karl-Titus Hoffmann, Dorothee Saur
Summary: Lesions in the left ventrolateral prefrontal cortex increase the risk of depressive symptoms 6 months poststroke, while lesions within the right hemisphere are unrelated to depressive symptoms. Early prediction factors for poststroke depression include depressive symptoms within the first 4 weeks poststroke.
Article
Multidisciplinary Sciences
Muhammad Aslam
Summary: A new F-test method for two counts data from the Poisson distribution under classical statistics is proposed in this paper. The test is applicable in situations where the count data is uncertain, in the interval, or indeterminate, and it has been shown to be efficient in application and comparison studies.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Ahmed Saleh, Ahmed Sultan, Mohamed A. Elashry, Ahmed Farag, Metwaly Ibrahim Mortada, Mayada A. Ghannam, Ahmed M. Saed, Sayed Ghoneem
Summary: This study found an association between TNF-alpha G-308 A gene polymorphism and the course and outcome of COVID-19 patients. People carrying the A allele of TNF-alpha polymorphism are more prone to COVID-19 infection, and the AA genotype is associated with a more aggressive pattern of the disease.
IMMUNOLOGICAL INVESTIGATIONS
(2022)
Review
Microbiology
Ahmed S. Sultan, Vasileios Ionas Theofilou, Areej Alfaifi, Daniel Montelongo-Jauregui, Mary-Ann Jabra-Rizk
Article
Immunology
Areej Alfaifi, Ahmed S. Sultan, Daniel Montelongo-Jauregui, Timothy F. Meiller, Mary Ann Jabra-Rizk
Summary: Despite various oral conditions observed in COVID-19 patients, the importance of the oral cavity as a site of SARS-CoV-2 infection is often overlooked. This study demonstrates that SARS-CoV-2 can replicate in salivary epithelial cells, leading to inflammation and atrophy of salivary glands. Histatin-5, an important component of saliva, is significantly reduced in COVID-19 patients, compromising its antimicrobial activity and potentially leading to oral symptoms such as dysesthesia and dysgeusia. These findings suggest a need for reassessment of the implications of COVID-19 on oral health.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Letter
Dentistry, Oral Surgery & Medicine
John K. Brooks, Julia H. Song, Ahmed S. Sultan
Article
Thermodynamics
Shimaa Zahran, Ahmed A. Sultan, Maher Bekheit, Mohamed R. Elmarghany
Summary: This study experimentally and numerically investigated turbulent air flow through a rectangular cross-sectional duct with one corrugated surface. The results showed that the corrugated surface considerably enhanced the heat transfer rate while slightly increasing the pressure drop.
CASE STUDIES IN THERMAL ENGINEERING
(2022)
Article
Physiology
Alaa El-Din H. Sayed, Hesham Taher, Hamdy A. M. Soliman, Alaa El-Din Salah El-Din
Summary: Dexamethasone at concentrations present in water bodies causes deleterious effects on blood biomarkers, biochemical, and antioxidant as well as immune upregulation in catfish until after depuration period.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Environmental Sciences
Hesham Taher, Mahmoud S. Sabra, Alaa El-Din Salah El-Din, Alaa El-Din H. Sayed
Summary: The chronic toxicity of metformin on catfish was investigated in this study. The results showed that metformin caused a significant decrease in antioxidants and electrolytes concentrations in the fish. The immune system of the exposed fish was suppressed, and oxidative stress and inflammation were induced. However, some parameters returned to normal levels after a 15-day recovery period.
TOXICOLOGY AND ENVIRONMENTAL HEALTH SCIENCES
(2022)
Article
Dentistry, Oral Surgery & Medicine
John K. Brooks, Arash Rostami, Cindy Q. Zhou, Ahmed S. Sultan
Summary: This article reports a case of a longstanding intraoral spindle cell lipoma that had become increasingly painful during mastication. Timely removal may reduce complications.
Article
Green & Sustainable Science & Technology
Ahmed Saad Soliman, Ahmed A. Sultan, Mohamed A. Sultan
Summary: This study experimentally and numerically investigated the melting process of paraffin wax in storage capsules of different shapes. The results showed that the shape of the storage capsule and the value of A(mush) greatly influence the melting process of the PCM.
Article
Engineering, Electrical & Electronic
Sultan Ahmad, Mohammed Yousuf Uddin
Summary: The Internet of Things (IoT) plays a significant role in various daily life applications, such as health monitoring, environmental monitoring, vehicle monitoring, crop monitoring, and material science. The proposed method aims to periodically monitor environmental factors by analyzing data collected from sensors and Nano electronics devices. The use of an IoT-dependent smart irrigation system can help achieve optimal resource utilization in precision farming. The proposed system relies on a smarter algorithm that considers sensed data along with weather forecast parameters for effective decision-making.
JOURNAL OF NANOELECTRONICS AND OPTOELECTRONICS
(2023)
Review
Dentistry, Oral Surgery & Medicine
David E. McReynolds, Advan Moorthy, James O'Connor Moneley, Mary Ann Jabra-Rizk, Ahmed S. Sultan
Summary: This interdisciplinary clinical review provides an overview of denture stomatitis, focusing on its etiopathogenesis, clinical features, and management strategies. The review emphasizes the importance of good oral and denture hygiene in preventing the formation of Candida-containing polymicrobial biofilms, which are responsible for this common infectious and inflammatory condition. Treatment of denture stomatitis not only improves oral health but also reduces the risk of associated complications such as aspirational pneumonia and mortality.
JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY
(2023)
Article
Cell Biology
Eman Hefni, Deepak Menon, Tao Ma, Emmanuel B. Asiedu, Ahmed Sultan, Timothy Meiller, Abraham Schneider, Akrit Sodhi, Silvia Montaner
Summary: This study investigated the molecular mechanisms of angiopoietin-like 4 (ANGPTL4) in the growth and dissemination of head and neck squamous cell carcinoma (HNSCC). It was found that ANGPTL4 was upregulated in premalignant cells and HNSCC cell lines, as well as tissue samples from patients with oral dysplasia and HNSCC. Furthermore, ANGPTL4 was found to promote tumor cell migration through its binding to neuropilin1 (NRP1) and subsequent phosphorylation of focal adhesion protein, paxillin (PXN), in a pathway dependent on ABL1 tyrosine kinase. Inhibition of ABL1 or NRP1 expression blocked this pathway and inhibited tumor cell migration.
CELLULAR SIGNALLING
(2023)
Article
Medicine, General & Internal
Mariam Ayed, Anwar Yazdani, Hind Esmaelili, Abdulla Alsaleh, Ahmed Sultan, Esam Alamad, Ali Bander, Hanouf Rawdhan
Summary: The objective of this study was to describe the impact of working during the COVID-19 pandemic on the mental health of resident physicians. The results showed that not being able to work with COVID-19 patients, work affecting study schedules, and loss of off-service training time were associated with higher stress and depression scores. Additionally, anxiety scores were significantly higher in females.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Meeting Abstract
Oncology
Rana Hamed Alneanaey, Nabil Taha, Mohammed Lebda, Aml Hashem, Ahmed Sultan
Meeting Abstract
Oncology
Rana Hamed Alneanaey, Nabil Taha, Mohammed Lebda, Aml Hashem, Ahmed Sultan