Macrophage Colony-Stimulating Factor Augments Tie2-Expressing Monocyte Differentiation, Angiogenic Function, and Recruitment in a Mouse Model of Breast Cancer

Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages

(2012) H. He et al.   BLOOD

Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling

(2012) Moritz Felcht et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting the ANG2/TIE2 Axis Inhibits Tumor Growth and Metastasis by Impairing Angiogenesis and Disabling Rebounds of Proangiogenic Myeloid Cells

(2011) Roberta Mazzieri et al.   CANCER CELL

Angiopoietin-2 TIEs Up Macrophages in Tumor Angiogenesis: Figure 1.

(2011) Michele De Palma et al.   CLINICAL CANCER RESEARCH

Angiopoietin 2 Stimulates TIE2-Expressing Monocytes To Suppress T Cell Activation and To Promote Regulatory T Cell Expansion

(2011) Seth B. Coffelt et al.   JOURNAL OF IMMUNOLOGY

The chemokine CXCL12 regulates monocyte-macrophage differentiation and RUNX3 expression

(2010) L. Sanchez-Martin et al.   BLOOD

Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity

(2010) David G. DeNardo et al.   CANCER AND METASTASIS REVIEWS

Angiopoietin-2 Regulates Gene Expression in TIE2-Expressing Monocytes and Augments Their Inherent Proangiogenic Functions

(2010) S. B. Coffelt et al.   CANCER RESEARCH

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships

(2009) F. Pucci et al.   BLOOD

Colony-stimulating factor-1-induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages

(2009) A. Jacquel et al.   BLOOD

CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages

(2009) David G. DeNardo et al.   CANCER CELL

Critical Role for GATA3 in Mediating Tie2 Expression and Function in Large Vessel Endothelial Cells

(2009) Haihua Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Anti-c-Fms Antibody Inhibits Orthodontic Tooth Movement

(2009) H. Kitaura et al.   JOURNAL OF DENTAL RESEARCH

M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis

(2009) Yoshiaki Kubota et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on Type I interferon signaling

(2009) Andrew J. Fleetwood et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tumor-Targeted Interferon-α Delivery by Tie2-Expressing Monocytes Inhibits Tumor Growth and Metastasis

(2008) Michele De Palma et al.   CANCER CELL

HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion

(2008) Rose Du et al.   CANCER CELL

High Expression of Macrophage Colony-Stimulating Factor in Peritumoral Liver Tissue Is Associated With Poor Survival After Curative Resection of Hepatocellular Carcinoma

(2008) Xiao-Dong Zhu et al.   JOURNAL OF CLINICAL ONCOLOGY

M-CSF Signals through the MAPK/ERK Pathway via Sp1 to Induce VEGF Production and Induces Angiogenesis In Vivo

(2008) Jennifer M. Curry et al.   PLoS One