AAV-Mediated Delivery of Zinc Finger Nucleases Targeting Hepatitis B Virus Inhibits Active Replication
出版年份 2014 全文链接
标题
AAV-Mediated Delivery of Zinc Finger Nucleases Targeting Hepatitis B Virus Inhibits Active Replication
作者
关键词
-
出版物
PLoS One
Volume 9, Issue 5, Pages e97579
出版商
Public Library of Science (PLoS)
发表日期
2014-05-15
DOI
10.1371/journal.pone.0097579
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Hepatitis B virus infection enhances susceptibility toward adeno-associated viral vector transductionin vitroandin vivo
- (2014) Marianna Hösel et al. HEPATOLOGY
- An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage
- (2014) Eli J. Fine et al. NUCLEIC ACIDS RESEARCH
- DNA cleavage enzymes for treatment of persistent viral infections: Recent advances and the pathway forward
- (2014) Nicholas D. Weber et al. VIROLOGY
- In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease
- (2014) Martine Aubert et al. Molecular Therapy-Nucleic Acids
- Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
- (2013) S. W. Cho et al. GENOME RESEARCH
- A novel therapeutic molecule against HTLV-1 infection targeting provirus
- (2013) A Tanaka et al. LEUKEMIA
- Inactivation of Hepatitis B Virus Replication in Cultured Cells and In Vivo with Engineered Transcription Activator-Like Effector Nucleases
- (2013) Kristie Bloom et al. MOLECULAR THERAPY
- An Efficient Antiviral Strategy for Targeting Hepatitis B Virus Genome Using Transcription Activator-Like Effector Nucleases
- (2013) Jieliang Chen et al. MOLECULAR THERAPY
- Selection and evaluation of clinically relevant AAV variants in a xenograft liver model
- (2013) Leszek Lisowski et al. NATURE
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
- (2013) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity
- (2013) Thomas J. Cradick et al. NUCLEIC ACIDS RESEARCH
- megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
- (2013) Sandrine Boissel et al. NUCLEIC ACIDS RESEARCH
- In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites
- (2013) Jeffry D. Sander et al. NUCLEIC ACIDS RESEARCH
- Gene- and Protein-Delivered Zinc Finger–Staphylococcal Nuclease Hybrid for Inhibition of DNA Replication of Human Papillomavirus
- (2013) Takashi Mino et al. PLoS One
- Targeted gene disruption to cure HIV
- (2013) Daniel Stone et al. Current Opinion in HIV and AIDS
- Predictors of Hepatitis B Cure Using Gene Therapy to Deliver DNA Cleavage Enzymes: A Mathematical Modeling Approach
- (2013) Joshua T. Schiffer et al. PLoS Computational Biology
- Viral diagnostics in the era of digital polymerase chain reaction
- (2012) Ruth Hall Sedlak et al. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
- Characterization of Nucleosome Positioning in Hepadnaviral Covalently Closed Circular DNA Minichromosomes
- (2012) Liping Shi et al. JOURNAL OF VIROLOGY
- Targeted DNA Mutagenesis for the Cure of Chronic Viral Infections
- (2012) J. T. Schiffer et al. JOURNAL OF VIROLOGY
- Systemic Errors in Quantitative Polymerase Chain Reaction Titration of Self-Complementary Adeno-Associated Viral Vectors and Improved Alternative Methods
- (2012) Paolo Fagone et al. Human Gene Therapy Methods
- Zinc-Finger Nuclease Based Genome Surgery: Its All About Specificity
- (2011) Eva-Maria Handel et al. CURRENT GENE THERAPY
- Genome Engineering With Zinc-Finger Nucleases
- (2011) Dana Carroll GENETICS
- Hepatic Gene Transfer in Neonatal Mice by Adeno-Associated Virus Serotype 8 Vector
- (2011) Lili Wang et al. HUMAN GENE THERAPY
- Meganuclease-mediated Inhibition of HSV1 Infection in Cultured Cells
- (2011) Stéphanie Grosse et al. MOLECULAR THERAPY
- In vivo genome editing restores haemostasis in a mouse model of haemophilia
- (2011) Hojun Li et al. NATURE
- An unbiased genome-wide analysis of zinc-finger nuclease specificity
- (2011) Richard Gabriel et al. NATURE BIOTECHNOLOGY
- Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection
- (2011) Vikram Pattanayak et al. NATURE METHODS
- Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B
- (2011) Amit C. Nathwani et al. NEW ENGLAND JOURNAL OF MEDICINE
- Successful Targeting and Disruption of an Integrated Reporter Lentivirus Using the Engineered Homing Endonuclease Y2 I-AniI
- (2011) Martine Aubert et al. PLoS One
- Zinc-finger Nucleases as a Novel Therapeutic Strategy for Targeting Hepatitis B Virus DNAs
- (2010) Thomas J Cradick et al. MOLECULAR THERAPY
- Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model
- (2009) Janaiah Kota et al. CELL
- Control of cccDNA function in hepatitis B virus infection
- (2009) Massimo Levrero et al. JOURNAL OF HEPATOLOGY
- The Sanger FASTQ file format for sequences with quality scores, and the Solexa/Illumina FASTQ variants
- (2009) Peter J. A. Cock et al. NUCLEIC ACIDS RESEARCH
- Optimized adeno-associated virus 8 produces hepatocyte-specific Cre-mediated recombination without toxicity or affecting liver regeneration
- (2008) Karen J. Ho et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Long-term correction of inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy
- (2008) G. P. Niemeyer et al. BLOOD
- Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy
- (2008) Henry Fechner et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Zinc Finger Proteins Designed To Specifically Target Duck Hepatitis B Virus Covalently Closed Circular DNA Inhibit Viral Transcription in Tissue Culture
- (2008) K. A. Zimmerman et al. JOURNAL OF VIROLOGY
- Physiological Promoters Reduce the Genotoxic Risk of Integrating Gene Vectors
- (2008) Daniela Zychlinski et al. MOLECULAR THERAPY
- Comparative Study of Anti-hepatitis B Virus RNA Interference by Double-stranded Adeno-associated Virus Serotypes 7, 8, and 9
- (2008) Chun-Chi Chen et al. MOLECULAR THERAPY
- Hepatitis B Virus Infection
- (2008) Jules L. Dienstag NEW ENGLAND JOURNAL OF MEDICINE
- Mutation analysis in nephronophthisis using a combined approach of homozygosity mapping, CEL I endonuclease cleavage, and direct sequencing
- (2007) Edgar A. Otto et al. HUMAN MUTATION
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation