标题
Identification of Druggable Cancer Driver Genes Amplified across TCGA Datasets
作者
关键词
-
出版物
PLoS One
Volume 9, Issue 5, Pages e98293
出版商
Public Library of Science (PLoS)
发表日期
2014-05-30
DOI
10.1371/journal.pone.0098293
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia (AML)
- (2015) Harald Herrmann et al. Oncotarget
- AMPK: A Contextual Oncogene or Tumor Suppressor?
- (2013) J. Liang et al. CANCER RESEARCH
- PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status
- (2013) Snehal Dabir et al. INTERNATIONAL JOURNAL OF CANCER
- KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy
- (2013) Emanuele Valtorta et al. INTERNATIONAL JOURNAL OF CANCER
- Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression
- (2013) Antonio F. Santidrian et al. JOURNAL OF CLINICAL INVESTIGATION
- Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening
- (2013) Lewis R. Vidler et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Potent Small-Molecule Inhibitor of the MDM2–p53 Interaction (MI-888) Achieved Complete and Durable Tumor Regression in Mice
- (2013) Yujun Zhao et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mutational landscape and significance across 12 major cancer types
- (2013) Cyriac Kandoth et al. NATURE
- Biomarkers of Residual Disease, Disseminated Tumor Cells, and Metastases in the MMTV-PyMT Breast Cancer Model
- (2013) Christian Franci et al. PLoS One
- Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications
- (2012) Cuilan Li et al. BMC CANCER
- KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer
- (2012) E Birkeland et al. BRITISH JOURNAL OF CANCER
- Cancer Epigenetics: From Mechanism to Therapy
- (2012) Mark A. Dawson et al. CELL
- Expression screening of 17q12-21 amplicon reveals GRB7 as an ERBB2-dependent oncogene
- (2012) Makoto Saito et al. FEBS LETTERS
- The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis
- (2012) Daechun Kang et al. GENES CHROMOSOMES & CANCER
- ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens
- (2012) D. D. Shao et al. GENOME RESEARCH
- Protein Inhibitor of Activated STAT3 (PIAS3) Protein Promotes SUMOylation and Nuclear Sequestration of the Intracellular Domain of ErbB4 Protein
- (2012) Maria Sundvall et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
- (2012) Sang-Min Jeon et al. NATURE
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- MDM4 is a key therapeutic target in cutaneous melanoma
- (2012) Agnieszka Gembarska et al. NATURE MEDICINE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think: Table I.
- (2011) Camille Lobry et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
- (2011) Ryan D. Morin et al. NATURE
- The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
- (2011) Craig J. Ceol et al. NATURE
- Integrated genomic analyses of ovarian carcinoma
- (2011) D. Bell et al. NATURE
- Amplification of the PDGFRA, KIT and KDR genes in glioblastoma: a population-based study
- (2011) Sumihito Nobusawa et al. NEUROPATHOLOGY
- Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
- (2011) H. W. Cheung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MET and KRAS Gene Amplification Mediates Acquired Resistance to MET Tyrosine Kinase Inhibitors
- (2010) V. Cepero et al. CANCER RESEARCH
- Grb7 Upregulation Is a Molecular Adaptation to HER2 Signaling Inhibition Due to Removal of Akt-Mediated Gene Repression
- (2010) Alessio Nencioni et al. PLoS One
- The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress
- (2009) Joanna R. Morris et al. NATURE
- Function and regulation of protein neddylation. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series
- (2008) Gwénaël Rabut et al. EMBO REPORTS
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- Epigenetics in Cancer
- (2008) Manel Esteller NEW ENGLAND JOURNAL OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now