Article
Public, Environmental & Occupational Health
Jose A. Rodrigues, Wonhee Cha, Rebekah E. Mosci, Sanjana Mukherjee, Duane W. Newton, Paul Lephart, Hossein Salimnia, Walid Khalife, James T. Rudrik, Shannon D. Manning
Summary: In a four-year active surveillance study at four metropolitan hospitals in Michigan, an increasing trend in Campylobacter jejuni infections was observed. Analysis of 214 C. jejuni isolates revealed widespread antibiotic resistance, with differences in infection rates by hospital type and patient characteristics associated with disease severity.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Food Science & Technology
Shanwei Tong, Luyao Ma, Jennifer Ronholm, William Hsiao, Xiaonan Lu
Summary: Campylobacter is a leading cause of bacterial gastroenteritis worldwide, and whole genome sequencing has been proven to be a robust and efficient tool for monitoring this microbe in food chain surveillance.
CURRENT OPINION IN FOOD SCIENCE
(2021)
Article
Microbiology
Myungseo Park, Jinshil Kim, Jill Feinstein, Kevin S. Lang, Sangryeol Ryu, Byeonghwa Jeon
Summary: Antibiotic tolerance in C. jejuni leads to the development of antibiotic resistance, particularly fluoroquinolone resistance. Exposure to ciprofloxacin or tetracycline induces antibiotic tolerance and promotes the emergence of fluoroquinolone-resistant C. jejuni clones. Alkyl hydroperoxide reductase plays a critical role in reducing the development of fluoroquinolone resistance after tolerance induction.
MICROBIOLOGY SPECTRUM
(2022)
Article
Microbiology
Emily Bordeleau, Peter J. Stogios, Elena Evdokimova, Kalinka Koteva, Alexei Savchenko, Gerard D. Wright
Summary: Apramycin, an aminoglycoside antibiotic, has a unique structure and resistance mechanism, making it a promising candidate in combating multidrug-resistant pathogens.
Article
Agriculture, Dairy & Animal Science
Gaia Casalino, Giancarlo Bozzo, Francesca Rita Dinardo, Francesco D'Amico, Michela Maria Dimuccio, Antonio Camarda, Edmondo Ceci, Diana Romito, Elena Circella
Summary: This study evaluated the incidence of C. jejuni and C. coli infection in laying hens housed in different rearing systems, with higher infection rates found in hens housed in aviaries. Antibiotic resistance was mainly detected among C. coli strains, highlighting the need to increase biosecurity measures.
Article
Infectious Diseases
Jose Manuel Silvan, Esperanza Guerrero-Hurtado, Alba Gutierrez-Docio, Marin Prodanov, Adolfo J. Martinez-Rodriguez
Summary: This study aimed to evaluate the antibacterial activity of olive leaf extracts against antibiotic-resistant Campylobacter strains. The results showed that the extracts exhibited strong inhibitory effects on both C. jejuni and C. coli, especially the extract rich in hydroxytyrosol and hydroxytyrosol glucosides. These findings suggest that optimizing the composition of olive leaf extracts can lead to improved treatment against Campylobacter strains.
Article
Infectious Diseases
Ongwae H. Zachariah, Mwamburi A. Lizzy, Kakai Rose, Mutuku M. Angela
Summary: This study found that approximately 33.1% of faecal samples from children under five years old presenting with diarrhoea at Kapsabet County Referral Hospital in Kenya tested positive for enteric pathogens. Shigella spp. and Campylobacter jejuni exhibited resistance to various antibiotics, highlighting the need for further investigation and development of effective therapeutic alternatives.
BMC INFECTIOUS DISEASES
(2021)
Article
Food Science & Technology
Xiang Wang, Qiyun Zhuo, Yi Hong, Yufan Wu, Qiang Gu, Dawei Yuan, Qingli Dong, Jingdong Shao
Summary: This study investigated the antibiotic resistance and virulence potential of 100 Campylobacter jejuni isolates from poultry meat. It found a correlation between the multilocus sequence types (MLST) of the isolates and their antibiotic resistance or virulence. The results provide critical information for the risk assessment of campylobacteriosis infection.
Article
Biotechnology & Applied Microbiology
Luyao Ma, Michael E. Konkel, Xiaonan Lu
Summary: This study found that C. jejuni biofilms significantly enhanced HGT, increasing the frequency up to 173-fold compared to planktonic cells. HGT in biofilms was not associated with biofilm biomass, cell density, or bacterial metabolic activity, but was correlated with extracellular DNA amount. The presence of synergistic HGT effect between different strains of C. jejuni was also observed.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Review
Immunology
Se-Hun Kim, Ramachandran Chelliah, Sudha Rani Ramakrishnan, Ayyappasamy Sudalaiyadum Perumal, Woo-Suk Bang, Momna Rubab, Eric Banan-Mwine Daliri, Kaliyan Barathikannan, Fazle Elahi, Eunji Park, Hyeon Yeong Jo, Su-Bin Hwang, Deog Hwan Oh
Summary: Campylobacter spp. are the leading cause of bacterial colon infections in humans globally, and their stress-adaptation mechanisms differ from other enteropathogenic bacteria, allowing them to survive in diverse environments and enhance their resistance mechanisms.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Qian Zhang, Hao-Tian Chi, Linrui Wu, Zixin Deng, Yi Yu
Summary: The biosynthesis of apramycin involves phosphorylation, deacetylation, and dephosphorylation steps with the enzymes AprU, AprP, and AprZ. Streptomyces tenebrarius uses C-5 phosphorylation and N-7' acetylation to avoid auto-toxicity of apramycin. This study provides insights for designing new generation AGAs to combat drug-resistant pathogens.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Microbiology
Ying-Shu Liao, Bo-Han Chen, Ru-Hsiou Teng, You-Wun Wang, Jui-Hsien Chang, Shiu-Yun Liang, Chi-Sen Tsao, Yu-Ping Hong, Hui-Yung Sung, Chien-Shun Chiou
Summary: Research in Taiwan has shown that C. coli and C. jejuni are highly resistant to most therapeutic antimicrobials. Whole-genome sequencing was used to analyze genetic diversity among isolates and genetic resistance determinants associated with antimicrobial resistance.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2022)
Article
Multidisciplinary Sciences
Zoe A. Hansen, Wonhee Cha, Brian Nohomovich, Duane W. Newton, Paul Lephart, Hossein Salimnia, Walid Khalife, Ashley Shade, James T. Rudrik, Shannon D. Manning
Summary: The study reveals that Campylobacter infection is associated with altered resistome composition and increased ARG diversity, raising concerns about the role of infection in the spread of resistance determinants.
SCIENTIFIC REPORTS
(2021)
Article
Biotechnology & Applied Microbiology
M. Lopez-Cantillo, A. Opazo-Capurro, C. Lopez-Joven, B. Vidal-Veuthey, L. Collado
Summary: This study evaluates the occurrence of Campylobacter jejuni and other related bacteria in retail beef liver and their antibiotic resistance. It suggests that beef liver could be an underestimated route for resistant C. jejuni transmission to humans.
LETTERS IN APPLIED MICROBIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Rima D. Shrestha, Agnes Agunos, Sheryl P. Gow, Csaba Varga
Summary: This study investigated antimicrobial resistance in turkeys in Canada and found a high prevalence of resistant Campylobacter isolates. Despite minimal use of tetracyclines and fluoroquinolones, a significant proportion of C. jejuni and C. coli isolates exhibited resistance to these drugs. Regional differences in resistance prevalence were observed, and certain antimicrobial classes may have contributed to the maintenance of resistance.
EPIDEMIOLOGY AND INFECTION
(2023)