Regulation of p53 Level by UBE4B in Breast Cancer

UBE4B levels are correlated with clinical outcomes in neuroblastoma patients and with altered neuroblastoma cell proliferation and sensitivity to epidermal growth factor receptor inhibitors

(2012) Peter E. Zage et al.   CANCER

Breast Cancer: A Neglected Disease for the Majority of Affected Women Worldwide

(2011) Ophira M. Ginsburg et al.   Breast Journal

UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation

(2011) Hong Wu et al.   CELL CYCLE

Specific domains of nucleolin interact with Hdm2 and antagonize Hdm2-mediated p53 ubiquitination

(2011) Purvi Bhatt et al.   FEBS Journal

UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53

(2011) Hong Wu et al.   NATURE MEDICINE

Estrogens, regulation of p53 and breast cancer risk: a balancing act

(2010) D. Joseph Jerry et al.   CELLULAR AND MOLECULAR LIFE SCIENCES