Telomerase Inhibitor Imetelstat (GRN163L) Limits the Lifespan of Human Pancreatic Cancer Cells

Detection of alternative lengthening of telomeres by telomere quantitative PCR

(2012) Loretta M. S. Lau et al.   NUCLEIC ACIDS RESEARCH

Targeting telomerase-expressing cancer cells

(2011) Michel M. Ouellette et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

Processive and Distributive Extension of Human Telomeres by Telomerase under Homeostatic and Nonequilibrium Conditions

(2011) Yong Zhao et al.   MOLECULAR CELL

Telomere dysfunction and chromosome instability

(2011) John P. Murnane   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Characterization of the DNA binding specificity of Shelterin complexes

(2011) Kyung H. Choi et al.   NUCLEIC ACIDS RESEARCH

Oligonucleotide N3′→P5′ Phosphoramidates andThio-Phoshoramidates as Potential Therapeutic Agents

(2010) Sergei M. Gryaznov   CHEMISTRY & BIODIVERSITY

The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth

(2010) C. O. Marian et al.   CLINICAL CANCER RESEARCH

Assembly and function of DNA double-strand break repair foci in mammalian cells

(2010) Simon Bekker-Jensen et al.   DNA REPAIR

Alternative lengthening of telomeres: models, mechanisms and implications

(2010) Anthony J. Cesare et al.   NATURE REVIEWS GENETICS

Telomerase: An RNP Enzyme Synthesizes DNA

(2010) E. H. Blackburn et al.   Cold Spring Harbor Perspectives in Biology

Widespread activation of the DNA damage response in human pancreatic intraepithelial neoplasia

(2009) Jan-Bart M Koorstra et al.   MODERN PATHOLOGY

DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity

(2009) Jeremy D Henson et al.   NATURE BIOTECHNOLOGY

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Pancreatic Cancer

(2008) Anirban Maitra et al.   Annual Review of Pathology-Mechanisms of Disease

Telomere Maintenance in Laser Capture Microdissection-Purified Barrett's Adenocarcinoma Cells and Effect of Telomerase Inhibition In vivo

(2008) M. A. Shammas et al.   CLINICAL CANCER RESEARCH

Telomerase inhibitor GRN163L inhibits myeloma cell growth in vitro and in vivo

(2008) M A Shammas et al.   LEUKEMIA