Clostridium perfringens Phospholipase C Induced ROS Production and Cytotoxicity Require PKC, MEK1 and NFκB Activation

Sphingomyelin regulates the transbilayer movement of diacylglycerol in the plasma membrane of Madin-Darby canine kidney cells

(2013) Yoshibumi Ueda et al.   FASEB JOURNAL

Protein Kinase C Regulates Human Pluripotent Stem Cell Self-Renewal

(2013) Masaki Kinehara et al.   PLoS One

Clostridium perfringens alpha-toxin induces the release of IL-8 through a dual pathway via TrkA in A549 cells

(2012) Masataka Oda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cell Signaling through Protein Kinase C Oxidation and Activation

(2012) Daniela Cosentino-Gomes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Reactive Oxygen Species and the MEK/ERK Pathway Are Involved in the Toxicity of Clostridium perfringens  -Toxin, a Prototype Bacterial Phospholipase C

(2012) L. Monturiol-Gross et al.   JOURNAL OF INFECTIOUS DISEASES

Phospholipases C and sphingomyelinases: Lipids as substrates and modulators of enzyme activity

(2012) Félix M. Goñi et al.   PROGRESS IN LIPID RESEARCH

Rottlerin and Cancer: Novel Evidence and Mechanisms

(2012) E. Maioli et al.   TheScientificWorldJOURNAL

Life-threatening clostridial infections

(2011) Dennis L. Stevens et al.   ANAEROBE

‘Flesh-eating’ necrotizing infections: must we amputate?

(2011) Amy E Bryant et al.   Expert Review of Anti-Infective Therapy

Exacerbation of pathology by oxidative stress in respiratory and locomotor muscles with Duchenne muscular dystrophy

(2011) John M. Lawler   JOURNAL OF PHYSIOLOGY-LONDON

Regulation of reactive oxygen species generation in cell signaling

(2011) Yun Soo Bae et al.   MOLECULES AND CELLS

The role of reactive oxygen species and autophagy in safingol-induced cell death

(2011) L-U Ling et al.   Cell Death & Disease

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

PKC and the control of localized signal dynamics

(2010) Carine Rosse et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Safingol (l-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway

(2009) Jesse Coward et al.   Autophagy

Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells

(2009) Ravi P. Sahu et al.   CARCINOGENESIS

The nuclear signaling of NF-κB: current knowledge, new insights and future perspectives

(2009) Fengyi Wan et al.   CELL RESEARCH

Phospholipase C and sphingomyelinase activities of the Clostridium perfringens α-toxin

(2009) Patricia Urbina et al.   CHEMISTRY AND PHYSICS OF LIPIDS

ERK and cell death: cadmium toxicity, sustained ERK activation and cell death

(2009) Patrick Martin et al.   FEBS Journal

The inflammatory response in the MPTP model of Parkinson’s disease is mediated by brain angiotensin: relevance to progression of the disease

(2009) Belen Joglar et al.   JOURNAL OF NEUROCHEMISTRY

C-reactive protein stimulates superoxide anion release and tissue factor activity in vivo

(2008) Sridevi Devaraj et al.   ATHEROSCLEROSIS