MAP3K8 (TPL2/COT) Affects Obesity-Induced Adipose Tissue Inflammation without Systemic Effects in Humans and in Mice

Tumor Progression Locus 2 (Tpl2) Deficiency Does Not Protect against Obesity-Induced Metabolic Disease

(2012) Graeme I. Lancaster et al.   PLoS One

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Tpl2 kinase signal transduction in inflammation and cancer

(2011) Maria Vougioukalaki et al.   CANCER LETTERS

Tumor Progression Locus 2 (TPL2) Regulates Obesity-Associated Inflammation and Insulin Resistance

(2011) J. W. Perfield et al.   DIABETES

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

How interleukin-1β induces gouty arthritis

(2010) Charles A. Dinarello   ARTHRITIS AND RHEUMATISM

Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase

(2010) Thorsten Gantke et al.   CELL RESEARCH

Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation

(2009) Jean-François Tanti et al.   CURRENT OPINION IN PHARMACOLOGY

Tpl2 Kinase Is Upregulated in Adipose Tissue in Obesity and May Mediate Interleukin-1  and Tumor Necrosis Factor-  Effects on Extracellular Signal-Regulated Kinase Activation and Lipolysis

(2009) J. Jager et al.   DIABETES

Tumor Progression Locus 2 (Map3k8) Is Critical for Host Defense against Listeria monocytogenes and IL-1  Production

(2009) L. A. Mielke et al.   JOURNAL OF IMMUNOLOGY