A Novel Iminosugar UV-12 with Activity against the Diverse Viruses Influenza and Dengue (Novel Iminosugar Antiviral for Influenza and Dengue)

In Vivo Therapeutic Protection against Influenza A (H1N1) Oseltamivir-Sensitive and Resistant Viruses by the Iminosugar UV-4

(2015) Eric J. Stavale et al.   PLoS One

Strain-specific antiviral activity of iminosugars against human influenza A viruses

(2014) S. Hussain et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial

(2014) Jenny G Low et al.   LANCET INFECTIOUS DISEASES

Glycosylation, Hypogammaglobulinemia, and Resistance to Viral Infections

(2014) Mohammed A. Sadat et al.   NEW ENGLAND JOURNAL OF MEDICINE

Emerging Principles for the Therapeutic Exploitation of Glycosylation

(2014) Martin Dalziel et al.   SCIENCE

An iminosugar with potent inhibition of dengue virus infection in vivo

(2013) Stuart T. Perry et al.   ANTIVIRAL RESEARCH

Antiviral therapies targeting host ER alpha-glucosidases: Current status and future directions

(2013) Jinhong Chang et al.   ANTIVIRAL RESEARCH

Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses

(2013) Jinhong Chang et al.   ANTIVIRAL RESEARCH

Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins

(2013) Dominic S. Alonzi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial

(2012) Satoru Watanabe et al.   ANTIVIRAL RESEARCH

Restricted processing of glycans by endomannosidase in mammalian cells

(2012) Nikolay V. Kukushkin et al.   GLYCOBIOLOGY

Competitive inhibitor of cellular α-glucosidases protects mice from lethal dengue virus infection

(2011) Jinhong Chang et al.   ANTIVIRAL RESEARCH

Therapeutic Strategies for Gaucher Disease: Miglustat (NB-DNJ) as a Pharmacological Chaperone for Glucocerebrosidase and the Different Thermostability of Velaglucerase Alfa and Imiglucerase

(2011) Olga Abian et al.   MOLECULAR PHARMACEUTICS

STAT2 Mediates Innate Immunity to Dengue Virus in the Absence of STAT1 via the Type I Interferon Receptor

(2011) Stuart T. Perry et al.   PLoS Pathogens

Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo

(2010) Jinhong Chang et al.   ANTIVIRAL RESEARCH

Enhanced Infection of Liver Sinusoidal Endothelial Cells in a Mouse Model of Antibody-Induced Severe Dengue Disease

(2010) Raphaël M. Zellweger et al.   Cell Host & Microbe

Cardif-Mediated Signaling Controls the Initial Innate Response to Dengue Virus In Vivo

(2009) S. T. Perry et al.   JOURNAL OF VIROLOGY

N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery

(2008) Stephanie Pollock et al.   AIDS

Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum α-glucosidase inhibition

(2008) Dominic S. Alonzi et al.   BIOCHEMICAL JOURNAL

A Mouse-Passaged Dengue Virus Strain with Reduced Affinity for Heparan Sulfate Causes Severe Disease in Mice by Establishing Increased Systemic Viral Loads

(2008) T. R. Prestwood et al.   JOURNAL OF VIROLOGY

CLEC5A is critical for dengue-virus-induced lethal disease

(2008) Szu-Ting Chen et al.   NATURE