Loss of Grainy Head-Like 1 Is Associated with Disruption of the Epidermal Barrier and Squamous Cell Carcinoma of the Skin

Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis

(2013) Iris Augustin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tracing the cellular origin of cancer

(2013) Cédric Blanpain   NATURE CELL BIOLOGY

The p53 target gene desmocollin 3 acts as a novel tumor suppressor through inhibiting EGFR/ERK pathway in human lung cancer

(2012) Tiantian Cui et al.   CARCINOGENESIS

Desmoplakin acts as a tumor suppressor by inhibition of the Wnt/β-catenin signaling pathway in human lung cancer

(2012) Linlin Yang et al.   CARCINOGENESIS

Mouse  -Defensin 14 (Defb14) Promotes Tumor Growth by Inducing Angiogenesis in a CCR6-Dependent Manner

(2012) J. Rohrl et al.   JOURNAL OF IMMUNOLOGY

SAA1 is over-expressed in plasma of non small cell lung cancer patients with poor outcome after treatment with epidermal growth factor receptor tyrosine-kinase inhibitors

(2012) Enrico Milan et al.   Journal of Proteomics

IL-17 Mediated Inflammation Promotes Tumor Growth and Progression in the Skin

(2012) Donggou He et al.   PLoS One

The Desmosomal Armadillo Protein Plakoglobin Regulates Prostate Cancer Cell Adhesion and Motility through Vitronectin-Dependent Src Signaling

(2012) Carrie A. Franzen et al.   PLoS One

Building the niche: The role of the S100 proteins in metastatic growth

(2012) Eugene Lukanidin et al.   SEMINARS IN CANCER BIOLOGY

Targeting of the Tumor Suppressor GRHL3 by a miR-21-Dependent Proto-Oncogenic Network Results in PTEN Loss and Tumorigenesis

(2011) Charbel Darido et al.   CANCER CELL

Immune functions of the skin

(2011) Christine Bangert et al.   CLINICS IN DERMATOLOGY

The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity

(2010) Yeliz Boglev et al.   DEVELOPMENTAL BIOLOGY

The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor

(2010) Christine Bolitho et al.   ENDOCRINE-RELATED CANCER

Role of the immediate early response 3 (IER3) gene in cellular stress response, inflammation and tumorigenesis

(2010) Alexander Arlt et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis

(2010) Veronica G. Beaudry et al.   PLoS Genetics

Reddish, scaly, and itchy: how proteases and their inhibitors contribute to inflammatory skin diseases

(2009) Ulf Meyer-Hoffert   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Epidermal Notch1 Loss Promotes Skin Tumorigenesis by Impacting the Stromal Microenvironment

(2009) Shadmehr Demehri et al.   CANCER CELL

Desmoglein 1–dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis

(2009) Spiro Getsios et al.   JOURNAL OF CELL BIOLOGY

30 years and a long way into p53 research

(2009) Pierre Hainaut et al.   LANCET ONCOLOGY

The Chemokine CXCL16 and Its Receptor, CXCR6, as Markers and Promoters of Inflammation-Associated Cancers

(2009) Merav Darash-Yahana et al.   PLoS One

Dysregulation of Human β-Defensin-2 Protein in Inflammatory Bowel Disease

(2009) Marian C. Aldhous et al.   PLoS One

Secreted CXCL1 Is a Potential Mediator and Marker of the Tumor Invasion of Bladder Cancer

(2008) H. Kawanishi et al.   CLINICAL CANCER RESEARCH

Perturbed desmosomal cadherin expression in grainy head-like 1-null mice

(2008) Tomasz Wilanowski et al.   EMBO JOURNAL

Abundant expression of CXCL9 (MIG) by stromal cells that include dendritic cells and accumulation of CXCR3+T cells in lymphocyte-rich gastric carcinoma

(2008) H Ohtani et al.   JOURNAL OF PATHOLOGY

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

(2008) Sachie Hiratsuka et al.   NATURE CELL BIOLOGY

Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity

(2008) Shadmehr Demehri et al.   PLOS BIOLOGY

Co-Regulation and Interdependence of the Mammalian Epidermal Permeability and Antimicrobial Barriers

(2007) Karin M. Aberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY