Cis-Regulatory Variants Affect CHRNA5 mRNA Expression in Populations of African and European Ancestry

Multiple isoforms and differential allelic expression of CHRNA5 in lung tissue and lung adenocarcinoma

(2013) Felicia S. Falvella et al.   CARCINOGENESIS

The α5 Subunit Regulates the Expression and Function of α4*-Containing Neuronal Nicotinic Acetylcholine Receptors in the Ventral-Tegmental Area

(2013) Susmita Chatterjee et al.   PLoS One

Integrative Modeling of eQTLs and Cis-Regulatory Elements Suggests Mechanisms Underlying Cell Type Specificity of eQTLs

(2013) Christopher D. Brown et al.   PLoS Genetics

Genome-Wide Association Studies IdentifyCHRNA5/3andHTR4in the Development of Airflow Obstruction

(2012) Jemma B. Wilk et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Genetics of Substance Dependence

(2012) Jen-Chyong Wang et al.   Annual Review of Genomics and Human Genetics

Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain

(2012) Dena G. Hernandez et al.   NEUROBIOLOGY OF DISEASE

Genetic Vulnerability and Susceptibility to Substance Dependence

(2011) Laura Jean Bierut   NEURON

In Vitro and Ex Vivo Analysis of CHRNA3 and CHRNA5 Haplotype Expression

(2011) Glenn A. Doyle et al.   PLoS One

The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study

(2011) Alexandra C. Nica et al.   PLoS Genetics

Nicotinic α5 receptor subunit mRNA expression is associated with distant 5′ upstream polymorphisms

(2010) Ryan M Smith et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Reduced RET expression in gut tissue of individuals carrying risk alleles of Hirschsprung's disease

(2010) Xiaoping Miao et al.   HUMAN MOLECULAR GENETICS

Promoter Polymorphisms and Transcript Levels of Nicotinic Receptor CHRNA5

(2010) Felicia S. Falvella et al.   JNCI-Journal of the National Cancer Institute

Variation in Nicotinic Acetylcholine Receptor Genes is Associated with Multiple Substance Dependence Phenotypes

(2010) Richard Sherva et al.   NEUROPSYCHOPHARMACOLOGY

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes

(2009) Nancy L. Saccone et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Haplotype and Cell Proliferation Analyses of Candidate Lung Cancer Susceptibility Genes on Chromosome 15q24-25.1

(2009) Y. Liu et al.   CANCER RESEARCH

Transcription Deregulation at the 15q25 Locus in Association with Lung Adenocarcinoma Risk

(2009) F. S. Falvella et al.   CLINICAL CANCER RESEARCH

Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

(2009) Jen C. Wang et al.   HUMAN MOLECULAR GENETICS

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes

(2009) Timothy B. Baker et al.   NICOTINE & TOBACCO RESEARCH

Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with ‘pleasurable buzz’ during early experimentation with smoking

(2008) Richard Sherva et al.   ADDICTION

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

(2008) Laura Jean Bierut et al.   AMERICAN JOURNAL OF PSYCHIATRY

A Risk Allele for Nicotine Dependence in CHRNA5 Is a Protective Allele for Cocaine Dependence

(2008) Richard A. Grucza et al.   BIOLOGICAL PSYCHIATRY

The CHRNA5/A3/B4 Gene Cluster Variability as an Important Determinant of Early Alcohol and Tobacco Initiation in Young Adults

(2008) Isabel R. Schlaepfer et al.   BIOLOGICAL PSYCHIATRY

Nicotinic Receptor Gene Variants Influence Susceptibility to Heavy Smoking

(2008) V. L. Stevens et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The CHRNA5-A3 Region on Chromosome 15q24-25.1 Is a Risk Factor Both for Nicotine Dependence and for Lung Cancer

(2008) Margaret R. Spitz et al.   JNCI-Journal of the National Cancer Institute

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

(2008) J C Wang et al.   MOLECULAR PSYCHIATRY

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

(2008) Rayjean J. Hung et al.   NATURE

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS

Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans

(2008) G. Joslyn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Candidate Gene Approach Identifies the CHRNA5-A3-B4 Region as a Risk Factor for Age-Dependent Nicotine Addiction

(2008) Robert B. Weiss et al.   PLoS Genetics