Decreased Galectin-9 and Increased Tim-3 Expression Are Related to Poor Prognosis in Gastric Cancer

Tim-3 Expression in Cervical Cancer Promotes Tumor Metastasis

(2013) Yang Cao et al.   PLoS One

Tim-3 Expression Defines Regulatory T Cells in Human Tumors

(2013) Jing Yan et al.   PLoS One

Ectopic Expression of TIM-3 in Lung Cancers

(2012) Xuewei Zhuang et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Galectin-9 Acts as a Prognostic Factor with Antimetastatic Potential in Hepatocellular Carcinoma

(2012) Zhao-Yang Zhang et al.   Asian Pacific Journal of Cancer Prevention

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells

(2012) R. G. Veenstra et al.   BLOOD

The Glycan-Binding Protein Galectin-9 Has Direct Apoptotic Activity toward Melanoma Cells

(2012) Valerie R. Wiersma et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Global cancer transitions according to the Human Development Index (2008–2030): a population-based study

(2012) Freddie Bray et al.   LANCET ONCOLOGY

Galectin-9 Controls CD40 Signaling through a Tim-3 Independent Mechanism and Redirects the Cytokine Profile of Pathogenic T Cells in Autoimmunity

(2012) Gisela M. Vaitaitis et al.   PLoS One

Galectin-9 Ameliorates Con A-Induced Hepatitis by Inducing CD4+CD25low/int Effector T-Cell Apoptosis and Increasing Regulatory T Cell Number

(2012) Kun Lv et al.   PLoS One

Prospects for TIM3-Targeted Antitumor Immunotherapy

(2011) S. F. Ngiow et al.   CANCER RESEARCH

Galectin-9 signaling prolongs survival in murine lung-cancer by inducing macrophages to differentiate into plasmacytoid dendritic cell-like macrophages

(2011) Takeshi Kadowaki et al.   CLINICAL IMMUNOLOGY

Tim-3 regulates pro- and anti-inflammatory cytokine expression in human CD14+ monocytes

(2011) Ying Zhang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Therapeutic potential of Galectin-9 in human disease

(2011) Valerie R. Wiersma et al.   MEDICINAL RESEARCH REVIEWS

Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

(2009) M. Nakayama et al.   BLOOD

Role of Tim-3/Galectin-9 Inhibitory Interaction in Viral-Induced Immunopathology: Shifting the Balance toward Regulators

(2009) S. Sehrawat et al.   JOURNAL OF IMMUNOLOGY

Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells

(2008) J. Klibi et al.   BLOOD

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

(2008) Masako Seki et al.   CLINICAL IMMUNOLOGY

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices

(2008) A. Nobumoto et al.   GLYCOBIOLOGY

Galectin-9 expression links to malignant potential of cervical squamous cell carcinoma

(2008) Meiyan Liang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

TIMs: central regulators of immune responses: Figure 1.

(2008) David A. Hafler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE