标题
RVX-208, an Inducer of ApoA-I in Humans, Is a BET Bromodomain Antagonist
作者
关键词
Small interfering RNAs, Chromatin, Histones, DNA-binding proteins, Transcriptional control, Transcription factors, Cholesterol, Lysine
出版物
PLoS One
Volume 8, Issue 12, Pages e83190
出版商
Public Library of Science (PLoS)
发表日期
2014-01-01
DOI
10.1371/journal.pone.0083190
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The bromodomain interaction module
- (2012) Panagis Filippakopoulos et al. FEBS LETTERS
- Druggability Analysis and Structural Classification of Bromodomain Acetyl-lysine Binding Sites
- (2012) Lewis R. Vidler et al. JOURNAL OF MEDICINAL CHEMISTRY
- Epigenetic protein families: a new frontier for drug discovery
- (2012) Cheryl H. Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting Epigenetic Readers in Cancer
- (2012) Mark A. Dawson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Anacetrapib, a Novel CETP Inhibitor: Pursuing a New Approach to Cardiovascular Risk Reduction
- (2011) D E Gutstein et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Effects of the CETP Inhibitor Evacetrapib Administered as Monotherapy or in Combination With Statins on HDL and LDL Cholesterol
- (2011) Stephen J. Nicholls et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains
- (2011) Chun-wa Chung et al. JOURNAL OF MEDICINAL CHEMISTRY
- Efficacy and Safety of a Novel Oral Inducer of Apolipoprotein A-I Synthesis in Statin-Treated Patients With Stable Coronary Artery Disease
- (2011) Stephen J. Nicholls et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Novel HDL-directed pharmacotherapeutic strategies
- (2011) Emil M. deGoma et al. Nature Reviews Cardiology
- How were new medicines discovered?
- (2011) David C. Swinney et al. NATURE REVIEWS DRUG DISCOVERY
- Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis
- (2011) Amit V. Khera et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages
- (2010) Margarita de la Llera-Moya et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- RVX-208
- (2010) Dana Bailey et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- A First-in-Man, Randomized, Placebo-Controlled Study to Evaluate the Safety and Feasibility of Autologous Delipidated High-Density Lipoprotein Plasma Infusions in Patients With Acute Coronary Syndrome
- (2010) Ron Waksman et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Suppression of inflammation by a synthetic histone mimic
- (2010) Edwige Nicodeme et al. NATURE
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- Heme Oxygenase 1 Determines Atherosclerotic Lesion Progression Into a Vulnerable Plaque
- (2009) Caroline Cheng et al. CIRCULATION
- Major Lipids, Apolipoproteins, and Risk of Vascular Disease
- (2009) The Emerging Risk Factors Collaboration* JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Mechanism of Action of Niacin
- (2008) Vaijinath S. Kamanna et al. AMERICAN JOURNAL OF CARDIOLOGY
- Association of Loss-of-Function Mutations in the ABCA1 Gene With High-Density Lipoprotein Cholesterol Levels and Risk of Ischemic Heart Disease
- (2008) Ruth Frikke-Schmidt JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- High-Density Lipoprotein Cholesterol, High-Density Lipoprotein Particle Size, and Apolipoprotein A-I: Significance for Cardiovascular Risk
- (2008) Wim A. van der Steeg et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein
- (2008) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Long-Term Interleukin-6 Levels and Subsequent Risk of Coronary Heart Disease: Two New Prospective Studies and a Systematic Review
- (2008) John Danesh et al. PLOS MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started