标题
Alzheimer’s Disease: Analyzing the Missing Heritability
作者
关键词
Alzheimers disease, Genome-wide association studies, Genetics of disease, Phenotypes, Apolipoprotein genes, Genetic loci, Next-generation sequencing, Alleles
出版物
PLoS One
Volume 8, Issue 11, Pages e79771
出版商
Public Library of Science (PLoS)
发表日期
2013-11-08
DOI
10.1371/journal.pone.0079771
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cigarette Smoking is a Risk Factor for Alzheimer's Disease: An Analysis Controlling for Tobacco Industry Affiliation
- (2017) Janine K. Cataldo et al. JOURNAL OF ALZHEIMERS DISEASE
- Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis
- (2012) S. H. Lee et al. HUMAN MOLECULAR GENETICS
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
- (2012) Thorlakur Jonsson et al. NATURE
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Meta-analysis identifies common variants associated with body mass index in east Asians
- (2012) Wanqing Wen et al. NATURE GENETICS
- A genome-wide association meta-analysis identifies new childhood obesity loci
- (2012) NATURE GENETICS
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- How next-generation sequencing is transforming complex disease genetics
- (2012) Helena Kilpinen et al. TRENDS IN GENETICS
- Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database
- (2012) Christina M. Lill et al. PLoS Genetics
- The Use of Next-Generation Sequencing in Movement Disorders
- (2012) Catharine E. Krebs et al. Frontiers in Genetics
- Using VAAST to Identify an X-Linked Disorder Resulting in Lethality in Male Infants Due to N-Terminal Acetyltransferase Deficiency
- (2011) Alan F. Rope et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Estimating Missing Heritability for Disease from Genome-wide Association Studies
- (2011) Sang Hong Lee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A generalizable hypothesis for the genetic architecture of disease: pleomorphic risk loci
- (2011) A. Singleton et al. HUMAN MOLECULAR GENETICS
- Identification of IL6R and chromosome 11q13.5 as risk loci for asthma
- (2011) Manuel AR Ferreira et al. LANCET
- Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
- (2011) Georg B. Ehret et al. NATURE
- A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer
- (2011) Christopher A Haiman et al. NATURE GENETICS
- Genome partitioning of genetic variation for complex traits using common SNPs
- (2011) Jian Yang et al. NATURE GENETICS
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
- (2011) Adam C Naj et al. NATURE GENETICS
- Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
- (2011) Paul Hollingworth et al. NATURE GENETICS
- Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
- (2011) Louise V Wain et al. NATURE GENETICS
- Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
- (2011) NATURE GENETICS
- Meta-Analysis for Genome-Wide Association Study Identifies Multiple Variants at the BIN1 Locus Associated with Late-Onset Alzheimer's Disease
- (2011) Xiaolan Hu et al. PLoS One
- GCTA: A Tool for Genome-wide Complex Trait Analysis
- (2010) Jian Yang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genetic Variation and Neuroimaging Measures in Alzheimer Disease
- (2010) Alessandro Biffi ARCHIVES OF NEUROLOGY
- Replication of CLU, CR1, and PICALM Associations With Alzheimer Disease
- (2010) Minerva M. Carrasquillo et al. ARCHIVES OF NEUROLOGY
- Robust relationship inference in genome-wide association studies
- (2010) Ani Manichaikul et al. BIOINFORMATICS
- MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes
- (2010) Yun Li et al. GENETIC EPIDEMIOLOGY
- Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals
- (2010) Jason J. Corneveaux et al. HUMAN MOLECULAR GENETICS
- Reimagining Alzheimer's Disease--An Age-Based Hypothesis
- (2010) K. Herrup JOURNAL OF NEUROSCIENCE
- Common SNPs explain a large proportion of the heritability for human height
- (2010) Jian Yang et al. NATURE GENETICS
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing
- (2010) J. C. Roach et al. SCIENCE
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
- (2009) Jean-Charles Lambert et al. NATURE GENETICS
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
- (2009) Denise Harold et al. NATURE GENETICS
- Genetic diagnosis by whole exome capture and massively parallel DNA sequencing
- (2009) Murim Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diagnosis and treatment of dementia: 1. Risk assessment and primary prevention of Alzheimer disease
- (2008) C. Patterson et al. CANADIAN MEDICAL ASSOCIATION JOURNAL
- Epistasis in sporadic Alzheimer's disease
- (2008) Onofre Combarros et al. NEUROBIOLOGY OF AGING
- Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis
- (2008) H. Shao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started