Vaccine-Induced Boosting of Influenza Virus-Specific CD4 T Cells in Younger and Aged Humans

An altered relationship of influenza vaccine-specific IgG responses with T cell immunity occurs with aging in humans

(2013) Ki Soo Kang et al.   CLINICAL IMMUNOLOGY

Increased T-bet is associated with senescence of influenza virus-specific CD8 T cells in aged humans

(2013) Douglas V. Dolfi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Evaluation of In Vitro Cross-Reactivity to Avian H5N1 and Pandemic H1N1 2009 Influenza Following Prime Boost Regimens of Seasonal Influenza Vaccination in Healthy Human Subjects: A Randomised Trial

(2013) Delia Bethell et al.   PLoS One

Increase in IFNγ−IL-2+ Cells in Recent Human CD4 T Cell Responses to 2009 Pandemic H1N1 Influenza

(2013) Jason M. Weaver et al.   PLoS One

Induction of ICOS+CXCR3+CXCR5+ TH Cells Correlates with Antibody Responses to Influenza Vaccination

(2013) S.-E. Bentebibel et al.   Science Translational Medicine

Cooperativity Between CD8+ T Cells, Non-Neutralizing Antibodies, and Alveolar Macrophages Is Important for Heterosubtypic Influenza Virus Immunity

(2013) Brian J. Laidlaw et al.   PLoS Pathogens

Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms

(2012) K. Kai McKinstry et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4+ T-Cell Expansion Predicts Neutralizing Antibody Responses to Monovalent, Inactivated 2009 Pandemic Influenza A(H1N1) Virus Subtype H1N1 Vaccine

(2012) Jennifer L. Nayak et al.   JOURNAL OF INFECTIOUS DISEASES

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors

(2012) T. M. Strutt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trivalent inactivated influenza vaccines induce broad immunological reactivity to both internal virion components and influenza surface proteins

(2012) Katherine A. Richards et al.   VACCINE

Induction of cross-protection against influenza A virus by DNA prime-intranasal protein boost strategy based on nucleoprotein

(2012) Jian Luo et al.   Virology Journal

Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

(2011) J. R. Teijaro et al.   JOURNAL OF IMMUNOLOGY

Annual Vaccination against Influenza Virus Hampers Development of Virus-Specific CD8+ T Cell Immunity in Children

(2011) R. Bodewes et al.   JOURNAL OF VIROLOGY

Influenza-Specific T Cells from Older People Are Enriched in the Late Effector Subset and Their Presence Inversely Correlates with Vaccine Response

(2011) Lisa E. Wagar et al.   PLoS One

Protective cellular responses elicited by vaccination with influenza nucleoprotein delivered by a live recombinant attenuated Salmonella vaccine

(2011) Shamaila Ashraf et al.   VACCINE

Age-related changes in memory and effector T cells responding to influenza A/H3N2 and pandemic A/H1N1 strains in humans

(2011) Xin Zhou et al.   VACCINE

Age-related changes in durability and function of vaccine-elicited influenza-specific CD4+ T-cell responses

(2011) Yolanda D. Mahnke et al.   VACCINE

Influenza vaccine responses in older adults

(2010) Janet E. McElhaney   AGEING RESEARCH REVIEWS

Potent CD8+ T-Cell Immunogenicity in Humans of a Novel Heterosubtypic Influenza A Vaccine, MVA-NP+M1

(2010) T. K. Berthoud et al.   CLINICAL INFECTIOUS DISEASES

Bim Dictates Naive CD4 T Cell Lifespan and the Development of Age-Associated Functional Defects

(2010) H. Tsukamoto et al.   JOURNAL OF IMMUNOLOGY

Memory CD4 T Cells Direct Protective Responses to Influenza Virus in the Lungs through Helper-Independent Mechanisms

(2010) J. R. Teijaro et al.   JOURNAL OF VIROLOGY

Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects

(2009) H. Tsukamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Effector and Memory CD8+ T Cell Responses to Smallpox and Yellow Fever Vaccines

(2008) Joseph D. Miller et al.   IMMUNITY

Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection

(2008) Joshua J. Obar et al.   IMMUNITY

Influenza A Virus Matrix Protein 1-Specific Human CD8+ T-Cell Response Induced in Trivalent Inactivated Vaccine Recipients

(2008) M. Terajima et al.   JOURNAL OF VIROLOGY

Memory CD8 T-cell compartment grows in size with immunological experience

(2008) Vaiva Vezys et al.   NATURE

CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator

(2008) Guifang Cai et al.   NATURE IMMUNOLOGY

Discordance between antibody and T cell responses in recipients of trivalent inactivated influenza vaccine

(2008) Mary Dawn T. Co et al.   VACCINE

In vitro evidence that commercial influenza vaccines are not similar in their ability to activate human T cell responses

(2008) Mary Dawn T. Co et al.   VACCINE

Multiparameter flow cytometric analysis of CD4 and CD8 T cell subsets in young and old people

(2008) Sven Koch et al.   Immunity & Ageing