标题
NF-κB-Induced IL-6 Ensures STAT3 Activation and Tumor Aggressiveness in Glioblastoma
作者
关键词
-
出版物
PLoS One
Volume 8, Issue 11, Pages e78728
出版商
Public Library of Science (PLoS)
发表日期
2013-11-12
DOI
10.1371/journal.pone.0078728
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
- (2013) A. Sottoriva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emerging insights into the molecular and cellular basis of glioblastoma
- (2012) G. P. Dunn et al. GENES & DEVELOPMENT
- NF- B, the first quarter-century: remarkable progress and outstanding questions
- (2012) M. S. Hayden et al. GENES & DEVELOPMENT
- JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease
- (2012) John J. O'Shea et al. IMMUNITY
- Signal transducer and activator of transcription 3 promotes angiogenesis and drives malignant progression in glioma
- (2012) Tiffany A. Doucette et al. NEURO-ONCOLOGY
- On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells
- (2012) Owen D. Stechishin et al. NEURO-ONCOLOGY
- The molecular profile of microglia under the influence of glioma
- (2012) W. Li et al. NEURO-ONCOLOGY
- Essential role of cooperative NF-κB and Stat3 recruitment to ICAM-1 intronic consensus elements in the regulation of radiation-induced invasion and migration in glioma
- (2012) D Kesanakurti et al. ONCOGENE
- Using the Heat-Shock Response To Discover Anticancer Compounds that Target Protein Homeostasis
- (2011) Sandro Santagata et al. ACS Chemical Biology
- Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
- (2011) S. I. Grivennikov et al. ANNALS OF THE RHEUMATIC DISEASES
- The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma
- (2011) K. P. L. Bhat et al. GENES & DEVELOPMENT
- Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB–mediated pathogenic pathways
- (2011) Vivek Swarup et al. JOURNAL OF EXPERIMENTAL MEDICINE
- An NF-κB p65-cIAP2 link is necessary for mediating resistance to TNF-α induced cell death in gliomas
- (2011) Xueyan Zhao et al. JOURNAL OF NEURO-ONCOLOGY
- Therapeutic Potential of AZD1480 for the Treatment of Human Glioblastoma
- (2011) B. C. McFarland et al. MOLECULAR CANCER THERAPEUTICS
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- NF-κB and STAT3 signaling in glioma: targets for future therapies
- (2010) George P Atkinson et al. Expert Review of Neurotherapeutics
- IL-17 Enhancement of the IL-6 Signaling Cascade in Astrocytes
- (2010) X. Ma et al. JOURNAL OF IMMUNOLOGY
- Discovery of 5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a Novel Inhibitor of the Jak/Stat Pathway
- (2010) Stephanos Ioannidis et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mechanisms of tumor necrosis factor-α-induced interleukin-6 synthesis in glioma cells
- (2010) Kumiko Tanabe et al. Journal of Neuroinflammation
- Glioma cancer stem cells induce immunosuppressive macrophages/microglia
- (2010) Adam Wu et al. NEURO-ONCOLOGY
- LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model
- (2009) B Fuh et al. BRITISH JOURNAL OF CANCER
- The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors
- (2009) Michael Hedvat et al. CANCER CELL
- Inflammation and Cancer: IL-6 and STAT3 Complete the Link
- (2009) Jacqueline Bromberg et al. CANCER CELL
- Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors
- (2009) Heehyoung Lee et al. CANCER CELL
- Effect of the alcoholic extract of Ashwagandha leaves and its components on proliferation, migration, and differentiation of glioblastoma cells: Combinational approach for enhanced differentiation
- (2009) Navjot Shah et al. CANCER SCIENCE
- Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice
- (2009) Leying Zhang et al. GLIA
- The transcriptional network for mesenchymal transformation of brain tumours
- (2009) Maria Stella Carro et al. NATURE
- NF- B as a Critical Link Between Inflammation and Cancer
- (2009) M. Karin Cold Spring Harbor Perspectives in Biology
- Constitutively Activated STAT3 Frequently Coexpresses with Epidermal Growth Factor Receptor in High-Grade Gliomas and Targeting STAT3 Sensitizes Them to Iressa and Alkylators
- (2008) H.-W. Lo et al. CLINICAL CANCER RESEARCH
- Loss of Protein Inhibitors of Activated STAT-3 Expression in Glioblastoma Multiforme Tumors: Implications for STAT-3 Activation and Gene Expression
- (2008) E. C. Brantley et al. CLINICAL CANCER RESEARCH
- NF-κB and cancer—identifying targets and mechanisms
- (2008) Willscott E Naugler et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- The ING4 Tumor Suppressor Attenuates NF- B Activity at the Promoters of Target Genes
- (2008) S. Nozell et al. MOLECULAR AND CELLULAR BIOLOGY
- Signal Transducer and Activator of Transcription-3: A Molecular Hub for Signaling Pathways in Gliomas
- (2008) E. C. Brantley et al. MOLECULAR CANCER RESEARCH
- Malignant Gliomas in Adults
- (2008) Patrick Y. Wen et al. NEW ENGLAND JOURNAL OF MEDICINE
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