IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1 Integrin Protein Levels

Integrin α5β1 simultaneously controls EGFR-dependent proliferation and Akt-dependent pro-survival signaling in epidermoid carcinoma cells

(2016) Galina E Morozevich et al.   Aging-US

miR-92a Inhibits Peritoneal Dissemination of Ovarian Cancer Cells by Inhibiting Integrin α5 Expression

(2013) Chifumi Ohyagi-Hara et al.   AMERICAN JOURNAL OF PATHOLOGY

Trop-2 Promotes Prostate Cancer Metastasis By Modulating  1 Integrin Functions

(2013) M. Trerotola et al.   CANCER RESEARCH

An Integrin Binding-defective Mutant of Insulin-like Growth Factor-1 (R36E/R37E IGF1) Acts as a Dominant-negative Antagonist of the IGF1 Receptor (IGF1R) and Suppresses Tumorigenesis but Still Binds to IGF1R

(2013) Masaaki Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Constitutively Activated β 1 Integrins Inhibits Prostate Cancer Metastasis

(2013) Yu-Chen Lee et al.   MOLECULAR CANCER RESEARCH

Coordinate Direct Input of Both KRAS and IGF1 Receptor to Activation of PI3 kinase in KRAS -Mutant Lung Cancer

(2013) Miriam Molina-Arcas et al.   Cancer Discovery

Endothelial Expression of TNF Receptor-1 Generates a Proapoptotic Signal Inhibited by Integrin  6 1 in Glioblastoma

(2012) P. Huang et al.   CANCER RESEARCH

Targeting the Insulin Growth Factor Receptor 1

(2012) Fernanda I. Arnaldez et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Cross-talk between Integrin α6β4 and Insulin-like Growth Factor-1 Receptor (IGF1R) through Direct α6β4 Binding to IGF1 and Subsequent α6β4-IGF1-IGF1R Ternary Complex Formation in Anchorage-independent Conditions

(2012) Masaaki Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways

(2012) Florian Steinberg et al.   JOURNAL OF CELL BIOLOGY

Insulin-like Growth Factor Receptor Inhibitors: Baby or the Bathwater?

(2012) D. Yee   JNCI-Journal of the National Cancer Institute

Sorting nexin 17 prevents lysosomal degradation of β1 integrins by binding to the β1-integrin tail

(2012) Ralph Thomas Böttcher et al.   NATURE CELL BIOLOGY

IGF-I enhances α5β1 integrin expression and cell motility in human chondrosarcoma cells

(2011) Chi-Ming Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Insulin-like growth factor 1 stimulation of androgen receptor activity requires β1A integrins

(2011) Aejaz Sayeed et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Talin1 Regulates Integrin Turnover To Promote Embryonic Epithelial Morphogenesis

(2011) J. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Insulin-like growth factor-I mediates neuroprotection in proteasome inhibition-induced cytotoxicity in SH-SY5Y cells

(2011) Benxu Cheng et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Talin1 Promotes Tumor Invasion and Metastasis via Focal Adhesion Signaling and Anoikis Resistance

(2010) S. Sakamoto et al.   CANCER RESEARCH

Ubiquitination of α5β1 Integrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-Integrin Complexes

(2010) Viola Hélène Lobert et al.   DEVELOPMENTAL CELL

Cross-talk between the insulin-like growth factor (IGF) axis and membrane integrins to regulate cell physiology

(2010) James Beattie et al.   JOURNAL OF CELLULAR PHYSIOLOGY

IGF-I induced rapid recruitment of integrin β1 to lipid rafts is Caveolin-1 dependent

(2009) B. Salani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pathways and mechanisms of endocytic recycling

(2009) Barth D. Grant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells

(2008) Weiguo Liu et al.   CARCINOGENESIS