Attenuation of Hyperlipidemia- and Diabetes-Induced Early-Stage Apoptosis and Late-Stage Renal Dysfunction via Administration of Fibroblast Growth Factor-21 Is Associated with Suppression of Renal Inflammation

Roles of histone deacetylation and AMP kinase in regulation of cardiomyocyte PGC-1α gene expression in hypoxia

(2013) Angela Ramjiawan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Fibroblast Growth Factor 21 Improves Insulin Resistance and Ameliorates Renal Injury indb/dbMice

(2013) H. W. Kim et al.   ENDOCRINOLOGY

Using a multi-staged strategy based on machine learning and mathematical modeling to predict genotype-phenotype risk patterns in diabetic kidney disease: a prospective case–control cohort analysis

(2013) Ross KK Leung et al.   BMC Nephrology

Fibroblast growth factor 21 protects against cardiac hypertrophy in mice

(2013) A. Planavila et al.   Nature Communications

Effects of Sevelamer on HbA1c, Inflammation, and Advanced Glycation End Products in Diabetic Kidney Disease

(2012) H. Vlassara et al.   Clinical Journal of the American Society of Nephrology

Fatty Acids - Induced Lipotoxicity and Inflammation

(2012) Stephane Savary et al.   CURRENT DRUG METABOLISM

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice

(2012) M. Y. Kim et al.   DIABETOLOGIA

FGF21 Is Increased by Inflammatory Stimuli and Protects Leptin-Deficientob/obMice from the Toxicity of Sepsis

(2012) Kenneth R. Feingold et al.   ENDOCRINOLOGY

Serum Fibroblast Growth Factor 21 Is Associated with Renal Function and Chronic Kidney Disease in Community-Dwelling Adults

(2012) Candace Crasto et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Diabetes-Induced Hepatic Pathogenic Damage, Inflammation, Oxidative Stress, and Insulin Resistance Was Exacerbated in Zinc Deficient Mouse Model

(2012) Chi Zhang et al.   PLoS One

Oxidative Stress and Diabetic Kidney Disease

(2011) Robert C. Stanton   Current Diabetes Reports

Resveratrol Improves Oxidative Stress and Protects Against Diabetic Nephropathy Through Normalization of Mn-SOD Dysfunction in AMPK/SIRT1-Independent Pathway

(2011) M. Kitada et al.   DIABETES

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

(2011) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe diabetic nephropathy in aging C57B6 mice

(2011) Jin Wu et al.   LABORATORY INVESTIGATION

Circulating FGF21 Levels Are Progressively Increased from the Early to End Stages of Chronic Kidney Diseases and Are Associated with Renal Function in Chinese

(2011) Zhuofeng Lin et al.   PLoS One

High-level expression and purification of soluble recombinant FGF21 protein by SUMO fusion in Escherichia coli

(2010) Huiyan Wang et al.   BMC BIOTECHNOLOGY

Lipotoxicity in Diabetic Nephropathy: The Potential Role of Fatty Acid Oxidation

(2010) M. Murea et al.   Clinical Journal of the American Society of Nephrology

Renal lipid metabolism and lipotoxicity

(2010) Ion Alexandru Bobulescu   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

The Effects of Inflammation on Lipid Accumulation in the Kidneys of Children with Primary Nephrotic Syndrome

(2010) Gaofu Zhang et al.   INFLAMMATION

Serum fibroblast growth factor–21 concentration is associated with residual renal function and insulin resistance in end-stage renal disease patients receiving long-term peritoneal dialysis

(2010) Seung Hyeok Han et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse

(2010) Klementina Fon Tacer et al.   MOLECULAR ENDOCRINOLOGY

Effects of polyunsaturated fatty acid consumption in diabetic nephropathy

(2010) Haim Shapiro et al.   Nature Reviews Nephrology

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway

(2010) Mary D. L. Chau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice

(2010) Yuguang Zhao et al.   TOXICOLOGY LETTERS

Attenuation of diabetes-induced renal dysfunction by multiple exposures to low-dose radiation is associated with the suppression of systemic and renal inflammation

(2009) Chi Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Low-carbohydrate diets reduce lipid accumulation and arterial inflammation in guinea pigs fed a high-cholesterol diet

(2009) Jose O. Leite et al.   ATHEROSCLEROSIS

Pathogenic perspectives for the role of inflammation in diabetic nephropathy

(2009) Antonio Rivero et al.   CLINICAL SCIENCE

An update on the lipid nephrotoxicity hypothesis

(2009) Xiong Z. Ruan et al.   Nature Reviews Nephrology

Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity

(2008) M. Mraz et al.   CLINICAL ENDOCRINOLOGY

Inflammation and Progressive Nephropathy in Type 1 Diabetes in the Diabetes Control and Complications Trial

(2008) J. Lin et al.   DIABETES CARE

The Role of Inflammatory Cytokines in Diabetic Nephropathy

(2008) J. F. Navarro-Gonzalez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY