Review
Endocrinology & Metabolism
Abdullah H. Altemani, Riyadh A. Alzaheb
Summary: This study aimed to review the role of lifestyle in the prevention of gestational diabetes mellitus (GDM). The results showed that dietary intervention had a significant positive effect on GDM prevention, while exercise intervention did not show a significant prevention effect. However, mild-moderate exercise during the first trimester was found to be effective in preventing GDM.
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Article
Medicine, General & Internal
Ashby F. Walker, Sian Graham, Louise Maple-Brown, Leonard E. Egede, Jennifer A. Campbell, Rebekah J. Walker, Alisha N. Wade, Jean Claude Mbanya, Judith A. Long, Chittaranjan Yajnik, Nihal Thomas, Osagie Ebekozien, Oriyomi Odugbesan, Linda A. Dimeglio, Shivani Agarwal
Summary: Diabetes is a serious chronic disease that disproportionately affects certain communities based on socioeconomic, gender, racial, and ethnic factors. This article emphasizes the need to address the broader social context and systems in order to achieve equity in diabetes care and outcomes on a global scale. It presents best practice approaches and action plans to target diabetes equity, and showcases international examples of addressing diabetes inequity within a larger social context.
Review
Endocrinology & Metabolism
Matladi Masete, Stephanie Dias, Nompumelelo Malaza, Sumaiya Adam, Carmen Pheiffer
Summary: Maternal diabetes, especially pregestational type 1 and type 2 diabetes, is associated with more frequent and severe pregnancy complications compared to gestational diabetes. Recent studies have shown the potential role of miRNAs in the pathophysiology of pregnancy-related disorders, including diabetes. However, there is a lack of miRNA profiling studies in pregnancies complicated by pregestational diabetes, highlighting the need for further research in this area.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Michael Fralick, Alicia J. Jenkins, Kamlesh Khunti, Jean Claude Mbanya, Viswanathan Mohan, Maria Ines Schmidt
Summary: This paper discusses the differences and barriers in diabetes treatment and proposes potential solutions.
NATURE REVIEWS ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Brenda Bongaerts, Suzanne Arnold, Bernard H. Charbonnel, Hungta Chen, Andrew Cooper, Peter Fenici, Marilia Gomes, Linong Ji, Kamlesh Khunti, Mikhail Kosiborod, Jesus Medina, Antonio Nicolucci, Marina Shestakova, Iichiro Shimomura, Fengming Tang, Hirotaka Watada, Wolfgang Rathmann
Summary: The study found a significant proportion of older patients with type 2 diabetes receiving inappropriately intensive glucose-lowering treatment and using high-risk medications, with notable regional variations. This highlights the importance of individualized care for older diabetic patients to avoid potential overtreatment and adverse effects.
BMJ OPEN DIABETES RESEARCH & CARE
(2021)
Review
Immunology
Xianliang Dai, Li Hua, Hui Chen, Qiheng Li, Wansheng Chen, Chun Liang
Summary: Diabetes mellitus is an autoimmune inflammatory and age-related disease. The thymus, as an important immune organ, plays a role in the immune and inflammatory response process. Based on previous studies, changes in thymus function may contribute to the development of diabetes and its complications through the regulation of insulin resistance and inflammatory cytokines. This review aims to summarize and discuss recent advances in understanding the influence of thymus function on diabetes.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Review
Medicine, General & Internal
Shivani Agarwal, Alisha N. Wade, Jean Claude Mbanya, Chittaranjan Yajnik, Nihal Thomas, Leonard E. Egede, Jennifer A. Campbell, Rebekah J. Walker, Louise Maple-Brown, Sian Graham
Summary: This paper uses new theoretical frameworks and a review of existing literature to discuss how structural inequity has accelerated the prevalence and impact of diabetes globally, and reviews various social determinants of health that affect diabetes outcomes.
Article
Endocrinology & Metabolism
Lauren A. Reid, Siyu Zheng, Jason A. Mendoza, Beth A. Reboussin, Alissa J. Roberts, Katherine A. Sauder, Jean M. Lawrence, Elizabeth Jensen, Leora Henkin, Kate Flory, Lisa M. Knight, Catherine Pihoker, Lawrence M. Dolan, Elaine M. Apperson, Angela D. Liese
Summary: This study aimed to evaluate the relationship between household food insecurity (HFI) and fear of hypoglycemia among young adults and adolescents with type 1 and type 2 diabetes, as well as their parents. The results showed that adults with type 1 and type 2 diabetes experiencing HFI had higher fear of hypoglycemia scores compared to those without HFI. Screening for HFI and fear of hypoglycemia can help healthcare providers customize diabetes education for individuals who have HFI and fear hypoglycemia.
Review
Biochemistry & Molecular Biology
Lowell Dilworth, Aldeam Facey, Felix Omoruyi
Summary: Adipose tissues, particularly brown and white adipose tissues, play key roles in communication and insulin sensitivity in the development and treatment of type 2 diabetes. Adipocytokines produced by adipose tissues, like leptin and adiponectin, vary in conditions such as metabolic dysfunction, diabetes, and inflammation. The regulation of satiety, energy metabolism, and insulin release by adipose tissues indicates their significance in the pathogenesis of diabetes mellitus and its complications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Medicine, General & Internal
Maria Mercedes Chang Villacreses, Rudruidee Karnchanasorn, Horng-Yih Ou, Raynald Samoa, Lee-Ming Chuang, Ken C. Chiu
Summary: A1C ≥ 48 mmol/mol (6.5%) has low sensitivity in diagnosing diabetes, especially in males, non-Hispanic White individuals, those in the third decade, and those with lower BMI. The risk of diabetic retinopathy increases significantly with A1C ≥ 48 mmol/mol (6.5%).
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Ulric Sena Abonie, Ama Kissiwaa Ampomah, Vincent Makinyi, Raphael Aseye Addo, Laureen Kumah
Summary: This study explored the relationship between physical activity patterns and quality of life in type 2 diabetes patients from a major tertiary hospital in Ghana. The results suggest that regular walking can improve energy and mobility, sexual functioning, social burden, and disease management, while vigorous-intensity activities are negatively related to anxiety and worry.
Article
Endocrinology & Metabolism
Katherine Ogurtsova, Leonor Guariguata, Noel C. W. Barengo, Paz Lopez-Doriga Ruiz, Julian Sacre, Suvi J. Karuranga, Hong J. Sun, Edward Boyko, Dianna Magliano
Summary: According to the 2021 estimates, nearly half of adults with diabetes are unaware of their condition. The highest proportions of undiagnosed diabetes were found in Africa, the Western Pacific, and South-East Asia regions, while the lowest proportion was observed in North America and the Caribbean.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2022)
Review
Endocrinology & Metabolism
Nan Li, Liang Zhang, Xintang Wang, Yue Zhou, Lijing Gong
Summary: This review provides a comprehensive elucidation of the molecular mechanisms underlying pyroptosis and the potential mechanism of exercise in the treatment of diabetes mellitus (DM) and its complications. Exercise can inhibit pyroptosis through the regulation of inflammasome pathways, offering promising potential for expanding preventive and therapeutic strategies for DM.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Integrative & Complementary Medicine
Hongju Dai, Qiurong Chen, Hongyu Huang, Kaili Wu, Xue Yang
Summary: Type 1 diabetes is an autoimmune disease causing insulin deficiency and hyperglycemia. Prompt diagnosis and treatment by nurses are crucial in managing the condition and addressing daily challenges.
ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE
(2022)
Review
Endocrinology & Metabolism
Shili Zhang, Yulan Cai, Chuzhen Meng, Xinyi Ding, Jiali Huang, Xiangrong Luo, Ying Cao, Fang Gao, Mengchen Zou
Summary: This review summarizes the association between gut and skin microbiota and diabetes mellitus (DM), highlighting their roles in the proinflammatory status of DM. Although there is evidence of a connection causing the same activated innate immune response, further studies are needed to explore the mechanism. These findings could provide insight for future DM prevention, diagnosis and treatment.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Letter
Surgery
Srijit Das, Subhra Dhar
INDIAN JOURNAL OF SURGERY
(2022)
Review
Biochemistry & Molecular Biology
S. Rao Sirasanagandla, Isehaq Al-Huseini, R. G. Sumesh Sofin, Srijit Das
Summary: Bisphenol A (BPA) is a commonly used industrial compound, and evidence suggests that perinatal exposure to BPA increases the risk of cardiovascular diseases. Developmental programming and epigenetic modifications of genes may play a role in this impact.
CURRENT MEDICINAL CHEMISTRY
(2022)
Review
Neurosciences
Choy Ker Woon, Wong Kah Hui, Razif Abas, Muhammad Huzaimi Haron, Srijit Das, Teoh Seong Lin
Summary: Alzheimer's disease (AD) is a common neurodegenerative disease in the elderly, with challenges in drug delivery to the brain due to BBB disruption. Nanotechnology offers a new approach to overcome these challenges, with the combination of natural product-loaded nanoparticles potentially being a new direction for future AD treatment.
CURRENT NEUROPHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Amro M. Soliman, Seong Lin Teoh, Srijit Das
Summary: This review discusses the innovative applications of fish gelatin in the food industry, drug delivery, and possible therapeutic applications. By using fish gelatin as a carrier for drug delivery and in other pharmaceutical applications, it can address health and religious concerns and provide more alternative options.
CURRENT PHARMACEUTICAL DESIGN
(2022)
Article
Neurosciences
Nor Haliza Mohamad Najib, Mohamad Fairuz Yahaya, Srijit Das, Seong Lin Teoh
Summary: This study aimed to investigate the effects of full-length human metallothionein 2 peptide (hMT2) on paraquat-induced brain injury in zebrafish. The results showed that hMT2 was able to reverse the effects of paraquat, reduce lipid peroxidation, and increase the number of dopaminergic neurons.
INTERNATIONAL JOURNAL OF NEUROSCIENCE
(2023)
Review
Endocrinology & Metabolism
Hussein F. Sakr, Srinivasa R. Sirasanagandla, Srijit Das, Abdulhadi I. Bima, Ayman Z. Elsamanoudy
Summary: The incidence of metabolic syndrome and diabetes mellitus is increasing globally. A low-carbohydrate ketogenic diet has been proposed as a potential solution to combat insulin resistance and improve overall health. This review discusses the mechanism of ketogenesis, the impact of low-carbohydrate ketogenic diet on overcoming insulin resistance, and its beneficial effects on metabolic, neurodegenerative, cardiovascular, and lipid disorders.
CURRENT DIABETES REVIEWS
(2023)
Review
Biochemistry & Molecular Biology
Ruchi Bhuyan, Sanat Kumar Bhuyan, Jatindra Nath Mohanty, Srijit Das, Norsham Juliana, Izuddin Fahmy Juliana
Summary: This article reviews the epidemiology, clinical features, diagnosis, and complications of periodontitis. It also discusses the association between periodontitis and various systemic diseases, and highlights the latest updates on molecular mechanisms, biomarkers, and treatment procedures, which are important for diagnostic and therapeutic purposes.
Article
Biochemistry & Molecular Biology
Siti Mariam Abdul Wahab, Khairana Husain, Ibrahim Jantan, Laiba Arshad, Md. Areeful Haque, Norsyahida Mohd Fauzi, Mohd Azlan Nafiah, Srijit Das
Summary: This study evaluated the immunosuppressive effects of Annona muricata leaves extract on different parameters of humoral and cellular immune responses. The extract exhibited dose-dependent inhibitory effects on neutrophil migration, reactive oxygen species production, phagocytic activity, and CD11b/CD18 integrin expression. It also suppressed the expression of ceruloplasmin, myeloperoxidase, and lysozyme in a dose-dependent manner.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
(2023)
Review
Nutrition & Dietetics
Norsham Juliana, Liyana Azmi, Nadia Mohd Effendy, Nur Islami Mohd Fahmi Teng, Izuddin Fahmy Abu, Nur Nabilah Abu Bakar, Sahar Azmani, Noor Anisah Abu Yazit, Suhaini Kadiman, Srijit Das
Summary: The circadian system in the human body responds to environmental changes, influences physiological processes, and optimizes behavior. The skeletal muscle circadian clock plays a critical role in lipid and glucose metabolism. Disturbance of the circadian rhythm can affect the musculoskeletal system, and nutritional strategies can help maintain its homeostasis. Active collaborations between nutritionists and physiologists in the field of chronobiology and chrononutrition are essential, as interventions based on these interactions can reduce morbidity and mortality.
Review
Oncology
Marjanu Hikmah Elias, Srijit Das, Nazefah Abdul Hamid
Summary: This systematic review and integrated bioinformatic analysis provide new insights into the key genes and pathways involved in the pathogenesis of cervical cancer, which can be beneficial for developing better screening and treatment strategies.
Review
Biochemistry & Molecular Biology
Yamamh Al-Jubori, Nazik Tayfour Babiker Ahmed, Rawan Albusaidi, James Madden, Srijit Das, Srinivasa Rao Sirasanagandla
Summary: This systematic review focuses on the effectiveness of gum arabic (GA) in the treatment of various diseases. The results show that GA has significant effects on lipid profiles, renal function, plaque, gingival scores, biochemical parameters, blood pressure, inflammatory markers, and adiposity. GA has been successfully used in the treatment of sickle cell anemia, rheumatoid arthritis, metabolic disorders, periodontitis, gastrointestinal conditions, and kidney diseases. The findings of this research are important for understanding the potential therapeutic applications of GA in clinical practice.
Review
Plant Sciences
Srijit Das, Hussein Sakr, Isehaq Al-Huseini, Raghu Jetti, Sara Al-Qasmi, Raju Sugavasi, Srinivasa Rao Sirasanagandla
Summary: There are various herbicides used in agriculture, including the water-soluble herbicide Atrazine (ATZ) which has been found to have toxic effects on different systems of the body. ATZ can enter the body through various routes and has been associated with deleterious effects on respiratory, reproductive, endocrine, central nervous, gastrointestinal, and urinary systems. Some studies have even shown a link between ATZ exposure and cancer in industrial workers. This review discusses the mechanism of ATZ toxicity and explores the potential use of natural products as alternative treatments.
Article
Medicine, General & Internal
Surapaneni Lakshmi Sravya, Jayshree Swain, Abhay Kumar Sahoo, Swayamsidha Mangaraj, Jayabhanu Kanwar, Pooja Jadhao, Srijit Das
Summary: This study aims to determine the prevalence and predictors of sarcopenia among individuals with type 2 diabetes mellitus (T2DM). The study found that the prevalence of sarcopenia was significantly higher among T2DM individuals compared to non-diabetics. Body mass index, physical activity, serum calcium levels, hypertension, and neuropathy were identified as significant predictors of sarcopenia.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Hussein F. Sakr, Srinivasa Rao Sirasanagandla, Srijit Das, Abdulhadi I. Bima, Ayman Z. Elsamanoudy
Summary: Factors such as aging, unhealthy lifestyle, snacking, a Western diet, and smoking contribute to high blood pressure and increase the risk of heart disease. A low-carbohydrate, high-fat diet can improve insulin sensitivity, reduce atherosclerosis risk factors, and help control blood pressure. This review emphasizes the importance of lifestyle changes and the potential benefits of the LCHF diet in managing hypertension and reducing the need for medication.
Article
Environmental Sciences
Noor Anisah Abu Yazit, Norsham Juliana, Suhaini Kadiman, Kamilah Muhammad Hafidz, Nur Islami Mohd Fahmi Teng, Nazefah Abdul Hamid, Nadia Effendy, Sahar Azmani, Izuddin Fahmy Abu, Nur Adilah Shuhada Abd Aziz, Srijit Das
Summary: POCD is cognitive decline after surgery. This study identified differentially expressed genes associated with POCD and found potential proteins for POCD diagnostic and predictive biomarkers. Understanding the molecular mechanisms of POCD will lead to early detection and intervention to reduce the severity of POCD.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
