Recombinant Thrombomodulin Protects Mice against Histone-Induced Lethal Thromboembolism

Circulating Histones Are Mediators of Trauma-associated Lung Injury

(2012) Simon T. Abrams et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Pathogenesis of Sepsis

(2011) Deborah J. Stearns-Kurosawa et al.   Annual Review of Pathology-Mechanisms of Disease

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

(2011) F. Semeraro et al.   BLOOD

Histones induce rapid and profound thrombocytopenia in mice

(2011) T. A. Fuchs et al.   BLOOD

Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice

(2011) Hai Huang et al.   HEPATOLOGY

Thrombomodulin: protectorate God of the vasculature in thrombosis and inflammation

(2011) T. ITO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Extracellular histones increase plasma thrombin generation by impairing thrombomodulin-dependent protein C activation

(2011) C. T. AMMOLLO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Neutrophil extracellular traps promote deep vein thrombosis in mice

(2011) A. BRILL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The Use of Spinning-Disk Confocal Microscopy for the Intravital Analysis of Platelet Dynamics in Response to Systemic and Local Inflammation

(2011) Craig N. Jenne et al.   PLoS One

DIC: Which laboratory tests are most useful

(2010) Marcel Levi et al.   BLOOD REVIEWS

B Cell-Derived Vascular Endothelial Growth Factor A Promotes Lymphangiogenesis and High Endothelial Venule Expansion in Lymph Nodes

(2010) B. Shrestha et al.   JOURNAL OF IMMUNOLOGY

Disseminated intravascular coagulation or extended intravascular coagulation in massive pulmonary embolism

(2010) M. LEVI   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Massive pulmonary embolism leading to cardiac arrest is associated with consumptive coagulopathy presenting as disseminated intravascular coagulation

(2010) J. M. LEITNER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

(2010) Steffen Massberg et al.   NATURE MEDICINE

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

(2010) B. McDonald et al.   SCIENCE

Coagulation and innate immune responses: can we view them separately?

(2009) M. Delvaeye et al.   BLOOD

Extracellular histones are major mediators of death in sepsis

(2009) Jun Xu et al.   NATURE MEDICINE

Sepsis: the dark side of histones

(2009) Catherine Chaput et al.   NATURE MEDICINE

Proteolytic Cleavage of High Mobility Group Box 1 Protein by Thrombin-Thrombomodulin Complexes

(2008) Takashi Ito et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY