Article
Critical Care Medicine
Federico C. Angriman, Laura R. Rosella, Patrick T. Lawler, Dennis M. Ko, Claudio Martin, Hannah C. Wunsch, Damon Scales
Summary: This study identified risk factors for major cardiovascular events in adult sepsis survivors, including age, sex, diabetes, hypertension, atrial fibrillation, chronic kidney disease, and sepsis characteristics. These findings have important implications for future research.
CRITICAL CARE MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Jianfang Zhou, Xu-Ying Luo, Guang-Qiang Chen, Hong-Liang Li, Ming Xu, Shuai Liu, Yan-Lin Yang, Guangzhi Shi, Jian-Xin Zhou, Linlin Zhang
Summary: This study found that sepsis is a common complication in critically ill post-craniotomy patients. Advanced age, male gender, hypertension, trauma, postoperative intracranial complications, and lower Glasgow Coma Scale on the first postoperative day were identified as independent risk factors for sepsis.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Obstetrics & Gynecology
Anne Kvie Sande, Ingvild Dalen, Erik Andreas Torkildsen, Ragnar Kvie Sande, Nils-Halvdan Morken
Summary: This study investigated the factors affecting the risk of preeclampsia and found that type 1 and type 2 diabetes, chronic kidney disease, and chronic hypertension were more strongly associated with preterm preeclampsia.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Article
Microbiology
Sara Ornaghi, Alice Maraschini, Marta Buoncristiano, Edoardo Corsi Decenti, Elisabetta Colciago, Irene Cetin, Serena Donati
Summary: Italy conducted a population-based study on maternal sepsis occurring before or after childbirth. The study found an incidence rate of 5.5 per 10,000 maternities. Genital, respiratory, and urinary tract infections were the predominant sources of infection, mainly caused by E. coli and polymicrobial infections. It is important to raise awareness of maternal sepsis and its risk factors and management.
Article
Medicine, General & Internal
Long Xue, Huiying Wang, YunZhen He, Mengyun Sui, Hongzheng Li, Lin Mei, Xiaohua Ying
Summary: This study investigates the incidence and risk factors of diabetes in the Chinese population aged 45 years and above. The results show an increasing trend in the incidence of diabetes without geographical variations. Age, obesity, and alcohol consumption are identified as risk factors for incident diabetes.
Article
Medicine, General & Internal
Rahul Gupta, Satyam Singh Jayant, Ashu Rastogi, Sanjay K. Bhadada, Anil Bhansali, Naresh Sachdeva, Sant Ram
Summary: This study estimated the incidence of type 2 diabetes and pre-diabetes in a population-based cohort from India. It found a high incidence of diabetes and pre-diabetes in Asian-Indians, which is partly attributed to sedentary lifestyle and obesity.
POSTGRADUATE MEDICAL JOURNAL
(2023)
Article
Infectious Diseases
Maria Slocker-Barrio, Jesus Lopez-Herce-Cid, Amaya Bustinza-Arriortua, Elena Fresan-Ruiz, Iolanda Jordan-Garcia, Juan Carlos de Carlos-Vicente, Elvira Morteruel-Arizcuren, Patricia Garcia-Soler, Montserrat Nieto-Moro, Cristina Schuffelmann, Sylvia Belda-Hofheinz, Laura Ximena Herrera-Castillo, Sonia Maria Uriona-Tuma, Laia Pinos-Tella, Yolanda Pena-Lopez
Summary: There is an alarming increase in multidrug-resistant (MDR) sepsis among children in the pediatric intensive care unit (PICU) in Spain, mainly caused by gram-negative bacteria (ESBL-Enterobacterales), with mostly community-onset infections. Malnourished infants and children who were on antibiotics 48 hours prior to PICU admission are at increased risk and require closer surveillance.
Article
Endocrinology & Metabolism
Y-F Lee, H-K Tsou, P-Y Leong, Y-H Wang, J. C-C Wei
Summary: The study, based on a large retrospective cohort research in Taiwan, revealed a significantly increased risk of osteoporosis in sepsis patients under 65 years old. The risk was particularly high for young patients aged 20-49 years and patients aged 50-64 years with sepsis compared to non-sepsis group.
OSTEOPOROSIS INTERNATIONAL
(2021)
Article
Critical Care Medicine
Federico Angriman, Laura C. Rosella, Patrick R. Lawler, Dennis T. Ko, Hannah Wunsch, Damon C. Scales
Summary: Adult sepsis survivors experience an increased risk of major cardiovascular events compared to survivors of a non-sepsis hospitalization.
INTENSIVE CARE MEDICINE
(2022)
Article
Oncology
Yu-Chiao Wang, Ching-Hung Lin, Shih-Pei Huang, Mingchih Chen, Tian-Shyug Lee
Summary: Recent research has found a link between sedentary behavior, sugary drink consumption, and an increased risk of female breast cancer. The study suggests that modifying these risk profiles through lifestyle changes could help reduce the incidence of breast cancer in Taiwanese women.
Article
Pediatrics
Ching-Min Chang, Kuang-Che Kuo, Wan-Hsuan Chen, Chung-Hao Su, Chuan-Pin Lee, Ko-Jung Chen, Yao-Hsu Yang, Ju-Bei Yen, Jiunn-Ming Sheen
Summary: A study found that maternal type 2 diabetes mellitus and non-dependent drug abuse increase the risk of offspring biliary atresia. Further research should focus on identifying additional maternal and pregnancy risk factors and understanding the underlying pathophysiology of this disease.
PEDIATRIC RESEARCH
(2023)
Article
Orthopedics
Arimatias Raitio, Susanna Heiskanen, Johanna Syvanen, Maarit K. K. Leinonen, Teemu Kemppainen, Eliisa Loyttyniemi, Matti Ahonen, Mika Gissler, Ilkka Helenius
Summary: The etiology and maternal risk factors for congenital vertebral defects are not clear. This nationwide register-based case-control study found that maternal pregestational diabetes and rheumatoid arthritis were significant risk factors. Additionally, estrogens and heparins, commonly used in assisted reproductive technologies, were associated with an increased risk. A sensitivity analysis also suggested a link between maternal smoking and an elevated risk of vertebral anomalies.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2023)
Article
Infectious Diseases
Oscar Moreno-Perez, Esperanza Merino, Jose-Manuel Leon-Ramirez, Mariano Andres, Jose Manuel Ramos, Juan Arenas-Jimenez, Santos Asensio, Rosa Sanchez, Paloma Ruiz-Torregrosa, Irene Galan, Alexander Scholz, Antonio Amo, Pilar Gonzalez-delaAleja, Vicente Boix, Joan Gil
Summary: This study found that Post-acute COVID-19 syndrome was detected in about half of COVID-19 survivors, with mostly mild symptoms. Radiological and spirometric changes were observed in less than 25% of patients, and no baseline clinical features behaved as independent predictors of Post-acute COVID-19 syndrome development.
JOURNAL OF INFECTION
(2021)
Article
Medicine, General & Internal
Ujue Fresan, Marcela Guevara, Camino Trobajo-Sanmartin, Cristina Burgui, Carmen Ezpeleta, Jesus Castilla
Summary: The study found that, in the general population, individuals with cardiovascular, cerebrovascular, and chronic kidney diseases, rather than those with hypertension alone, should be considered as high-risk groups for COVID-19 hospitalization and severe COVID-19.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Sangsoo Han, Jiwon Park, Sangun Nah, Hae-Dong Jang, Kyungdo Han, Jae-Young Hong
Summary: Underweight is an important modifiable risk factor for fractures. A large population cohort study found a significant association between the severity of underweight and fracture risk.
SCIENTIFIC REPORTS
(2022)
Article
Pediatrics
Jonathan Ducey, Ann M. Kennedy, Louise Linsell, Kerry Woolfall, Nigel J. Hall, Chris Gale, Cheryl Battersby, Gareth Penman, Marian Knight, Nick Lansdale
Summary: This study reports the perspectives of 166 respondents from 27 UK neonatal surgical centres regarding the timing of neonatal stoma closure, showing concordance in target time for closure but high variability in practice. A considerable proportion of respondents use weight instead of time to determine when to close a neonatal stoma. Thematic analysis identified key themes influencing decision-making, mainly related to nutrition, growth, and stoma complications.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2022)
Article
Pediatrics
Oliver Burdall, Benjamin Allin, Kathryn Ford, Amit Gupta, Kokila Lakhoo, Marian Knight, Nigel J. Hall
Summary: This study aimed to investigate the relationship between timing of re-introduction of feeds following surgery for Necrotising Enterocolitis (NEC) and important early outcomes. The results showed that early feed reintroduction following laparotomy for NEC is safe in appropriate cases, and there is currently no evidence to support a minimum period of 7 days nil by mouth post-surgery.
JOURNAL OF PEDIATRIC SURGERY
(2022)
Article
Obstetrics & Gynecology
Jonathan L. Richardson, Sally Stephens, Lucy C. Chappell, Helen Campbell, Gayatri Amirthalingam, Shennae O'Boyle, Antoaneta Bukasa, Marian Knight, Kenneth K. Hodson
Summary: This article discusses a national study on the vaccination of pregnant women with COVID-19 vaccines and presents preliminary data collected up to June 15, 2021. The results show that the Pfizer-BioNTech mRNA vaccine is the most common, with most women being vaccinated in their second or third trimester mainly due to occupational infection risk.
OBSTETRIC MEDICINE
(2023)
Article
Obstetrics & Gynecology
Anna B. C. Humphreys, Louise Linsell, Marian Knight
Summary: This study found that timely prophylactic antibiotics could reduce the risk of infection after operative vaginal birth, regardless of the type of perineal trauma. The use of episiotomy, forceps birth, primiparity, and overweight were associated with an increased risk of infection after operative vaginal birth.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Public, Environmental & Occupational Health
J. M. Molenaar, L. van der Meer, L. C. M. Bertens, E. F. de Vries, A. J. M. Waelput, M. Knight, E. A. P. Steegers, J. C. Kiefte-de Jong, J. N. Struijs
Summary: This study aimed to identify classes of vulnerability among pregnant women in the Netherlands using pre-pregnancy data on social risk and protective factors, and validate these classes against adverse outcomes. The study found that vulnerability in pregnant women was characterized by high risk factors in a specific domain and protective factors in others. Furthermore, multidimensional vulnerability was associated with adverse outcomes such as premature birth and caesarean section.
EUROPEAN JOURNAL OF PUBLIC HEALTH
(2023)
Editorial Material
Health Care Sciences & Services
Audrey Lyndon, Dana-Ain Davis, Anjana E. Sharma, Karen A. Scott
BMJ QUALITY & SAFETY
(2023)
Article
Obstetrics & Gynecology
Marian Knight
OBSTETRICIAN & GYNAECOLOGIST
(2023)
Article
Anesthesiology
J. H. Bamber, R. Goldacre, D. N. Lucas, S. Quasim, M. Knight
Summary: Ethnic inequalities exist in obstetric anaesthetic care in the UK, with black women more likely to receive general anaesthesia during caesarean section births and Asian women less likely to receive neuraxial anaesthesia during vaginal births. Further research is needed to understand the causes of these disparities and to address potential remediable factors such as access to appropriate care.
Article
Obstetrics & Gynecology
P. L. M. de Vries, C. Deneux-Tharaux, D. Baud, K. K. Chen, S. Donati, F. Goffinet, M. Knight, R. D'Souzah, M. Sueters, T. van den Akker
Summary: This study compared guidelines on prevention and management of postpartum haemorrhage (PPH) from eight high-income countries. The results show a lack of strong evidence in many areas, indicating the need for a universal definition of (severe) PPH and consensus on blood loss measurement. Future research should focus on the timing and sequence of interventions and their impact on maternal outcomes. The quality of guidelines varied considerably. Rating: 9/10.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Obstetrics & Gynecology
A. Vierin, G. Vandenberghe, K. Bloemenkamp, S. Berlage, L. Colmorn, C. Deneux-Tharaux, S. Donati, M. Gissler, M. Knight, J. Langhoff-Roos, P. G. Lindqvist, B. Maier, J. van Roosmalen, J. Zwart, K. Roelens
Summary: This study analyzed atypical cases of uterine rupture, including those occurring in unscarred, preterm or prelabour uteri. The study found that these cases are extremely rare but can result in severe maternal and perinatal outcomes.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Letter
Hematology
Marian Knight, Cathy Nelson-Piercy
BRITISH JOURNAL OF HAEMATOLOGY
(2023)
Article
Nursing
Kathleen R. Simpson, Joanne Spetz, Caryl L. Gay, Jason Fletcher, Gay L. Landstrom, Audrey Lyndon
Summary: This study aimed to examine the relationship between hospital characteristics and adherence to the Association of Women's Health, Obstetric and Neonatal Nurses (AWHONN) nurse staffing guidelines. Findings showed that nurses generally had strong adherence to the guidelines in their hospitals. However, higher birth volume, having a neonatal intensive care unit, teaching status, and higher percentage of births paid by Medicaid were associated with lower adherence scores.
Article
Nutrition & Dietetics
Rachel A. Ryan, Allison Doub Hepworth, Audrey Lyndon, Jessica Dauz Bihuniak
Summary: This study examined the prevalence and effects of galactagogue use among breastfeeding women in the United States, and compared galactagogue use based on different maternal characteristics. The results showed that a majority of mothers used galactagogues to increase milk production, highlighting the need for research on the safety and efficacy of galactagogues and improved breastfeeding support.
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2023)
Editorial Material
Obstetrics & Gynecology
Marian Knight
OBSTETRICIAN & GYNAECOLOGIST
(2023)
Article
Medicine, General & Internal
Marian Knight, Kathryn Bunch, Nicola Vousden, Anita Banerjee, Philippa Cox, Fiona Cross-Sudworth, Mandish K. Dhanjal, Jenny Douglas, Joanna Girling, Sara Kenyon, Rohit Kotnis, Roshni Patel, Judy Shakespeare, Derek Tuffnell, Meg Wilkinson, Jennifer J. Kurinczuk
Summary: This research reveals the existence of multiple structural and other biases in maternity care in the UK. Some ethnic minority women experience lack of nuanced care, microaggressions, and clinical, social, and cultural complexity during the care process. Further study on the impact of microaggressions is needed.