Article
Spectroscopy
Sujun Wang, Hui Zhou, Chunlin Xiong, Lin Zhou, Jingfang Han, Xiaohan Cao, Si Chen, Ziyong Li
Summary: Two novel acceptor-acceptor (A-A) type DTE derivatives (4a and 4b) were synthesized with efficient photochromism. The molecules showed solvent-dependence and excellent photoswitching behaviors in different solvents and polymer films. The study also revealed the dominant role of strong acceptor effects in the photochromic performance.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Ju Hui Yun, Kyung Hyung Lee, Jun Yeob Lee
Summary: The benzoylphenyltriazine acceptor is explored as a strong acceptor for TADF emitters due to its high external quantum efficiency. By adding a weak electron-withdrawing benzoyl unit, the acceptor's electron-accepting strength is improved, leading to enhanced light emission performance of TADF emitters. Comparing with a phenyltriazine-based emitter, the benzoylphenyltriazine acceptor shows superior delayed-fluorescence characteristics with a higher quantum efficiency.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Chemistry, Applied
Hong Chen, Qianqian Liu, Jiamin Luo, Yiliang Zhang, Zixia Liang, Yuanyuan Yang, Ziyong Li, Shanchao Zhao, Xiumei Tian
Summary: A new donor-acceptor-type dithienylethene TDC displays NIR-like photochromic properties under UV/NIR light, with effective photochromic properties and fluorescent switching behavior observed in solid and aggregated states, as well as unexpected aggregation-controlled photochromism in H2O/DMSO mixtures.
Review
Chemistry, Multidisciplinary
C. P. Keshavananda Prabhu, Kenkera Rayappa Naveen, Jaehyun Hur
Summary: TADF materials are highly valued in OLEDs, and ADA-based TADF materials, known for their efficient charge transfer, have shown significant potential in high electroluminescent OLEDs. This comprehensive review provides insights into the molecular design, photophysical mechanisms, device architectures, and current challenges of ADA-based TADF materials.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Materials Science, Multidisciplinary
Dingli Liang, Zeying Guo, Yangzhe Su, Fan Zhou, Min Wang, Weinan Chen, Gang Zhou
Summary: Inserting a conjugated bridge between the two pyridinium units of the viologen is an effective approach to tuning the colorations of the viologen derivatives. The relationship between the charge density on the viologen bridge and the related photochromic and electrochromic properties has been rarely studied. Three conjugated bridges with different charge densities were incorporated between the two pyridinium units of ammonium-functionalized viologens, expanding the coloration scope and improving the chromic properties. An EC device based on AQV hydrogel exhibited high optical contrast, fast switching time, and no decay in optical contrast after 1000 cycles.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Chemistry, Inorganic & Nuclear
Yi-Ming Di, Meng-Hua Li, Ming-Hua You, Shu-Quan Zhang, Mei-Jin Lin
Summary: Donor-acceptor hybrid crystals are a new type of crystalline material with the ability to display room temperature phosphorescence. The incorporation of photosensitive core-substituted NDIs can greatly affect the light-sensitive properties of the hybrids. The heavy-atom effect contributes to the remarkable room temperature phosphorescence observed in these hybrid crystals.
INORGANIC CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
Baoling Li, Yabing Gan, Ke Yang, E. Pang, Xiaojie Ren, Shaojing Zhao, Dan He, Fuwen Zhao, Benhua Wang, Peng Yin, Xiangzhi Song, Minhuan Lan
Summary: This study designed and synthesized a molecular structure for multidimensional imaging-guided photodynamic/photothermal therapy. The resultant nanoparticle possesses NIR absorption, photoacoustic imaging, NIR-II fluorescence imaging capabilities, as well as the ability to generate singlet oxygen, hydroxyl radicals, and heat simultaneously.
SCIENCE CHINA-MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Dojin Kim, Ayse Aktalay, Nickels Jensen, Kakishi Uno, Mariano L. Bossi, Vladimir N. Belov, Stefan W. Hell
Summary: This article introduces a supramolecular system based on a fluorescent diarylethene and cucurbit[7]uril, which exhibits good fluorescence brightness and fatigue resistance in aqueous solutions. By encapsulating the switchable fluorescent molecule in the supramolecular system, its application in bioimaging and protein labeling is greatly improved.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Analytical
Jie-Yu Yue, Zi-Xian Pan, Li-Ping Song, Wen-Jiang Yu, Hong Zheng, Jian-Cheng Wang, Peng Yang, Bo Tang
Summary: Amine determination is crucial for various applications, and the construction of a mixed-linkage donor-acceptor covalent organic framework (DSE-COF) has shown great potential in this field. DSE-COF displays superior fluorescent responses to different types of aliphatic amines and can quantitatively detect cadaverine content in actual pork samples. The use of DSE-COF-based test papers enables rapid monitoring of cadaverine in real pork samples, showcasing the potential application of COFs in food quality inspection.
ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Moumi Mandal, Dipanjan Banik, Anirban Karak, Saikat Kumar Manna, Ajit Kumar Mahapatra
Summary: This review highlights recent advancements (2019-2022) in spiropyran-merocyanine based fluorogenic and chromogenic probes for the selective detection of various metal ions, anions, neutral analytes, and pH. The design strategies, sensing mechanisms, and biological and environmental applications are precisely explained.
Article
Agricultural Engineering
Heyu Zhang, Ji Fan, Wei Wang, Dan Yu
Summary: This study develops smart cotton fabrics with synchronous positive and negative photochromic and fluorescent color-changing properties, which can respond to both visible and ultraviolet light. Photochromic cotton fabrics have potential applications in various fields, such as UV protection, pattern switching, and information encryption.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Chemistry, Multidisciplinary
Anais C. Bourges, Benjamien Moeyaert, Thi Yen Hang Bui, Franziska Bierbuesse, Wim Vandenberg, Peter Dedecker
Summary: In this study, a general analytical model of fluorescent protein photochromism is developed and applied to spectroscopic measurements on six different labels. The approach provides quantitative explanations for phenomena such as positive and negative switching, limitations in photochromism contrast, and the variation in initial switching cycles from subsequent ones. Additionally, it allows for the measurement of all four isomerization quantum yields involved in the switching process for the first time.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Katsuya Mutoh, Natsuho Moriyama, Jiro Abe
Summary: The development of visible or near-infrared (NIR) light-responsive fast photoswitchable molecules has attracted attention due to their non-invasive features for controlling physical and chemical properties of materials and biological tissues. A new molecular design was proposed to enhance the thermal back-reaction of a negative photochromic molecule, BN-ImD. Additionally, a novel photoreaction product with a unique eight-membered ring structure was generated by irradiating a BN-ImD derivative with visible light, providing intriguing insights for the future development of fast negative photochromic molecules.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Vitaly A. Podshibyakin, Evgenii N. Shepelenko, Olga Yu Karlutova, Lyudmila G. Kuzmina, Alexander D. Dubonosov, Vladimir A. Bren, Vladimir Minkin
Summary: An effective approach to synthesize diarylethene-amino acid hybrids DE-Gly, DE-AABA and DE-DAA was developed with moderate to good yields. The structures and properties of the obtained compounds were confirmed by X-ray diffraction and NMR spectroscopy. The hybrids exhibit reversible modulation of internal emission and good fatigue resistance under successive irradiation with light of specific wavelengths.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Applied
Ziwei Lin, Sheng Wang, Qing Yan, Qinghua Yan, Derong Cao
Summary: It has been demonstrated that Cu2+ can drive the linear-to-cyclic isomerization of DASAs in acetonitrile, accelerating the rate of color fading, and verifying the universal applicability of the mechanism by which copper ions discolor DASAs. Furthermore, Cu2+ can be used as an eraser for DASA derived ink and as a Cu2+ sensor with high selectivity and sensitivity.
Article
Food Science & Technology
Yao Xiao, Kailin Li, Ji Bian, Hang Liu, Xiaotong Zhai, Emad El-Omar, Lin Han, Lan Gong, Min Wang
Summary: This study investigates the effect of Urolithin A (UA) on diabetes-associated cognitive impairment in a mouse model of type 2 diabetes mellitus (T2DM) induced by a high-fat diet (HFD) and streptozotocin (STZ). The results show that UA treatment can attenuate cognitive impairment and reduce levels of metabolic endotoxemia and proinflammatory cytokines in serum. UA also suppresses gut/brain inflammation, improves gut barrier function, and restores the dysregulation of genes involved in N-glycan biosynthesis. Unlike metformin, the beneficial effects of UA are independent of the gut microbiome and short-chain fatty acids. These findings suggest that UA has the potential to be a novel pharmacological target for diabetes therapy by manipulating the gut-brain axis and N-glycan metabolism.
MOLECULAR NUTRITION & FOOD RESEARCH
(2022)
Article
Medicine, General & Internal
Ningning Zhang, Zeyu Wang, Jiayu Lv, Shuwen Zhang, Yang Liu, Tian Liu, Wang Li, Lan Gong, Xiaodong Zhang, Emad M. El-Omar, Wei Lu
Summary: This study investigated the gut microbiota characteristics in patients with hepatocellular carcinoma (HCC) with microvascular invasion (MVI) and established a microbial prediction model of HCC-MVI. The results showed significant differences in gut microbiota composition between the HCC-MVI group and those without vascular invasion. The established prediction model had a high diagnostic accuracy. The gut microbiome characteristics of HCC-MVI patients were associated with tumor microenvironment.
FRONTIERS IN MEDICINE
(2022)
Review
Nutrition & Dietetics
Yonghui Dong, Xue Wu, Lin Han, Ji Bian, Caian He, Emad El-Omar, Lan Gong, Min Wang
Summary: Cardiovascular disease is a leading global health issue, and anthocyanins have been shown to have antioxidant, anti-inflammatory, and anti-aging effects, providing protection against cardiovascular diseases.
Review
Nutrition & Dietetics
Kailin Li, Yao Xiao, Ji Bian, Lin Han, Caian He, Emad El-Omar, Lan Gong, Min Wang
Summary: Urolithin A (Uro A) is a dietary metabolite with potential health benefits in various diseases. It has been found to improve pancreatic diseases by activating autophagy and inhibiting endoplasmic reticulum stress, resulting in reduced oxidative stress, inflammation, and apoptosis.
Article
Nutrition & Dietetics
Zhixin Luo, Mengqian Li, Qiong Yang, Yuhong Zhang, Fang Liu, Lan Gong, Lin Han, Min Wang
Summary: Ferulic acid (FA) has a protective effect on high-fat diet-induced non-alcoholic fatty liver disease (NAFLD) by activating PPARα to decrease triacylglycerol accumulation and increase energy expenditure.
Article
Multidisciplinary Sciences
Jingjing Jiang, Yuyu Li, Zeyu Sun, Lan Gong, Xuehui Li, Fan Shi, Jian Yao, Yuting Meng, Xiaohua Meng, Qiong Zhang, Yuchong Wang, Xiaoling Su, Hongyan Diao
Summary: This study discovered that lncNSPL is highly expressed in monocytes of patients infected with influenza A virus (IAV). By blocking the interaction between RIG-I and TRIM25, lncNSPL limits the production of antiviral mediators, promoting IAV replication and immune evasion.
Article
Microbiology
Jianing Chen, Ping Zeng, Lan Gong, Xujun Zhang, Zongxin Ling, Kefan Bi, Fan Shi, Kaihang Wang, Qiong Zhang, Jingjing Jiang, Yanhui Zhang, Toshimitsu Uede, Emad M. El-Omar, Hongyan Diao
Summary: The study found that osteopontin (OPN) levels were elevated in individuals with obesity compared to healthy controls, with a positive correlation between OPN levels and body mass index (BMI). OPN exacerbated high-fat diet-induced metabolic disorders and gut dysbiosis. OPN regulated the gut microbiota by decreasing the adhesion of Lactobacillus to intestinal epithelial cells.
Editorial Material
Medicine, General & Internal
Ding Shi, Silvia Turroni, Lan Gong, Wenrui Wu, Howard Chi Ho Yim
FRONTIERS IN MEDICINE
(2022)
Article
Nutrition & Dietetics
Zhixin Luo, Mengqian Li, Jiachuan Yang, Jia Li, Yao Zhang, Fang Liu, Emad El-Omar, Lin Han, Ji Bian, Lan Gong, Min Wang
Summary: This study found that ferulic acid (FA) can reduce high cholesterol levels caused by a high-fat diet. It does so by increasing the excretion of bile acids in the feces. FA activates the enzyme CYP7A1 in the liver, which biosynthesizes bile acids from cholesterol. This new mechanism discovered in the study may be related to the anti-obesity and hypoglycemic effects of FA.
FRONTIERS IN NUTRITION
(2022)
Article
Virology
Fan Zhang, Andrew Gia, Guowei Chen, Lan Gong, Jason Behary, Georgina L. Hold, Amany Zekry, Xubo Tang, Yanni Sun, Emad El-Omar, Xiao-Tao Jiang
Summary: Viruses are abundant and important in ecosystems, and the two methods of whole genome shotgun metagenome and viral-like particle enriched metagenome sequencing are commonly used for comparing viruses in different environments. In this study, both methods were applied to investigate the stool virome in HCC patients and healthy controls, and they both successfully identified altered viral profiles in HCC patients. Ultra-deep sequencing recovered more viruses, and VLPM method can detect RNA viruses. Using both methods would capture different parts of the total virome and identify shared and specific viral signatures.
Review
Biochemistry & Molecular Biology
Kailin Li, Ji Bian, Yao Xiao, Da Wang, Lin Han, Caian He, Lan Gong, Min Wang
Summary: In recent years, there has been a significant increase in age-related diseases worldwide due to longer life expectancy. The aging pancreas undergoes various morphological and pathological changes, which can predispose individuals to diseases such as diabetes, dyspepsia, pancreatic ductal adenocarcinoma, and pancreatitis. Pancreatic senescence is associated with underlying factors including genetic damage, DNA methylation, endoplasmic reticulum stress, mitochondrial dysfunction, and inflammation. This review article discusses the alterations in morphologies and functions of the aging pancreas, particularly beta-cells, and summarizes the mechanisms of pancreatic senescence to identify potential targets for treating aging-related diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Mingsheng Cai, Bin Xiao, Yuanfang Wang, Kezhen Wang, Wenqi Luo, Jiangqin Fu, Shuai Wang, Shenyu Deng, Bolin Li, Lan Gong, Jiayi Zhong, Li Hu, Lingxia Pan, Liding Wang, Yintao Liu, Chen Huang, Xiaoqing Li, Qiyuan Zeng, Haoran Kang, Linhai Li, Jie Zan, Tao Peng, Haidi Yang, Meili Li
Summary: In this study, it was found that the surface protein gp110 of Epstein-Barr virus (EBV) plays an important role in regulating the host's innate immunity. Gp110 inhibits NF-KB promoter activity and the production of NF-KB-regulated cytokines. It interacts with the transcription factor p65, limiting its activation and nuclear translocation. These findings suggest that gp110 is a vital component for EBV to antagonize the host's innate immune response and contribute to the understanding of EBV infectivity and pathogenesis.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Daouda A. K. Traore, Von Vergel L. Torres, Naureen Akhtar, Alexandra M. Gummer, Sarena F. Flanigan, Fasseli Coulibaly, Vicki Adams, James C. Whisstock, Julian I. Rood
Summary: This study describes a major DNA transfer system in the Gram-positive pathogen Clostridium perfringens which participates in the dissemination of antibiotic resistance and virulence genes. The coupling protein TcpA, an essential ATPase, is proposed to provide the mechanical force for DNA transfer. Structural analysis reveals that TcpA shares structural similarities with the FtsK DNA translocase, suggesting a possible evolution of conjugation in C. perfringens from bacterial chromosome segregation.
Article
Food Science & Technology
Yao Xiao, Kailin Li, Ji Bian, Yao Zhang, Jia Li, Hang Liu, Yingzhi Ye, Lin Han, Lan Gong, Min Wang
Summary: This study investigates the effects and mechanisms of Urolithin A (UA) on cognitive impairment in a mouse model of type 2 diabetes mellitus (T2DM) induced by high-fat diet and streptozotocin. The results show that UA can attenuate cognitive impairment by suppressing endoplasmic reticulum stress and Tau hyperphosphorylation in the brain. UA also reduces oxidative stress, abnormal energy metabolism, and apoptosis in damaged neuronal cells. Atp2a3 is identified as a potential target gene of UA that plays a role in intracellular calcium homeostasis, ER stress, and apoptosis. UA's protective effects against ER stress and apoptosis are abolished by over-expression of Atp2a3. Overall, this study suggests that UA could be a potential therapeutic target for neurodegeneration and stress damage by regulating Atp2a3 expression.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Chemistry, Physical
Larissa dos Santos Silva Araujo, Leah Watson, Daouda A. K. Traore, Giuseppe Lazzara, Leonardo Chiappisi
Summary: The inclusion complexes of alkyl ethoxy carboxylates with α-cyclodextrin and β-cyclodextrin were studied. The complexation process was found to be enthalpically driven and independent of pH. The complexes self-assembled into highly-ordered supramolecular aggregates, with different morphologies influenced by the number of ethylene oxides in the surfactants and the cyclodextrin cavity size.
