Cathepsin L Plays a Role in Quinolinic Acid-Induced NF-Κb Activation and Excitotoxicity in Rat Striatal Neurons

An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid

(2014) Yan Wang et al.   Autophagy

Coordination of autophagy with other cellular activities

(2013) Yan Wang et al.   ACTA PHARMACOLOGICA SINICA

Hyperactivation of the Mammalian Degenerin MDEG Promotes Caspase-8 Activation and Apoptosis

(2012) Ji-An Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p53 Mediates autophagy activation and mitochondria dysfunction in kainic acid-induced excitotoxicity in primary striatal neurons

(2012) X.X. Dong et al.   NEUROSCIENCE

Cathepsin L is involved in 6-hydroxydopamine induced apoptosis of SH-SY5Y neuroblastoma cells

(2011) Bei Xiang et al.   BRAIN RESEARCH

Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells

(2011) Ning Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

A new pathway that regulates 53BP1 stability implicates Cathepsin L and vitamin D in DNA repair

(2011) Ignacio Gonzalez-Suarez et al.   EMBO JOURNAL

Differential effects on p53-mediated cell cycle arrest vs. apoptosis by p90

(2011) C. Dai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular and cellular mechanisms of excitotoxic neuronal death

(2010) Yan Wang et al.   APOPTOSIS

Neuroprotection by donepezil against glutamate excitotoxicity involves stimulation of α7 nicotinic receptors and internalization of NMDA receptors

(2010) H Shen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Autophagy and protein aggregation after brain ischemia

(2010) Chunli Liu et al.   JOURNAL OF NEUROCHEMISTRY

Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides

(2010) Lydiane Funkelstein et al.   NEUROPEPTIDES

Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases

(2009) Xiao-xia Dong et al.   ACTA PHARMACOLOGICA SINICA

p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum

(2009) Xing-Ding Zhang et al.   Autophagy

The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

(2009) Zhenyu Yue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Olomoucine inhibits cathepsin L nuclear translocation, activates autophagy and attenuates toxicity of 6-hydroxydopamine

(2009) Xi-Feng Fei et al.   BRAIN RESEARCH

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms

(2009) Yan Wang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cathepsin L, target in cancer treatment?

(2009) Jacqueline M. Lankelma et al.   LIFE SCIENCES

Contribution of p53-mediated Bax transactivation in theaflavin-induced mammary epithelial carcinoma cell apoptosis

(2008) Lakshmishri Lahiry et al.   APOPTOSIS

Structural basis of target recognition by Atg8/LC3 during selective autophagy

(2008) Nobuo N. Noda et al.   GENES TO CELLS

Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

(2008) Yoshinobu Ichimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes

(2008) E. Shvets et al.   JOURNAL OF CELL SCIENCE

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE